Saw Palmetto para Alopecia Androgenética
ABaseado em 21 estudos (2 meta-analyses, 4 RCTs) com 2,123 participantes no total. 20/21 estudos mostram efeitos positivos.
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A
Conclusão
Saw palmetto is well-supported by clinical research as a natural supplement that may help slow hair loss and support regrowth in androgenetic alopecia by naturally inhibiting DHT production.
- 95% of studies (20/21) show positive effects, including 4 RCTs and 2 meta-analyses
- Works as a natural 5-alpha reductase inhibitor, reducing DHT levels
- Both oral supplementation and topical application have demonstrated benefits
- Generally well-tolerated, though less potent than prescription finasteride
Key Study Findings
Review
The Over-The-Counter Finasteride Alternative: A Critical Review of Saw Palmetto's Efficacy, Safety, and Regulatory Concerns.
Dose: None
vs: None
Outcome: None
Efeito: None
None
População: None
RCT
n=80
24 weeks
Double-blind
Oral Supplementation with l-Cystine, Serenoa repens, Cucurbita pepo, and Pygeum africanum in Chronic Telogen Effluvium …
Dose: 1 capsule daily (l-Cystine, Serenoa repens, Cucurbita pepo, Pygeum africanum, vitamins, micronutrien
vs: Placebo
Efeito: MD=+12.3 hairs/cm2 at 6 months
p<0.05
narrative review
Addressing the Root Causes of Female Hair Loss and Non-Pharmaceutical Interventions.
Dose: None
vs: Placebo
Efeito: None
None
narrative review
Herbal Remedies for Hair Loss: A Review of Efficacy and Safety.
Dose: varies by remedy and study
vs: Placebo
Efeito: None
None
systematic review
n=1658
Double-blind
Effects of dietary supplements on androgenetic alopecia: a systematic review and network meta-analysis.
Dose: various dietary supplements (Nutrafol, apple extract, tocotrienols, pumpkin seed oil, Cistanche/Lami
vs: Placebo
Efeito: None
None
review
Single-blind
Do Non-Prescription Products Help in Managing Androgenic Alopecia?
Dose: Various non-prescription agents: procyanidin, cetirizine, caffeine, Oryza sativa bran, pumpkin seed
vs: Placebo
Efeito: Considerable improvements in one or more parameters across 13 included studies
None
Key Statistics
22
Estudos
2123
Participantes
↑
Positive
A
Nota
Referenced Papers
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Effects of dietary supplements on androgenetic alopecia: a systematic review and network meta-analysis.
Systematic Review
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2023
9 citações
Real-World, Open-Label Study of the Efficacy and Safety of a Novel Serum in Androgenetic Alopecia.
Other
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8 citações
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8 citações
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41 citações
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24 citações
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100 citações
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27 citações
The Australasian journal …
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20 citações
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Dosagens Comumente Utilizadas
- general:
- 320 mg/day
- hairloss:
- 320 mg/day standardized extract
Limite superior: Not established
Dosagens Estudadas em Pesquisas
| Dosagem | Duração | Efeito | N |
|---|---|---|---|
| None | -- | Neutral | -- |
| 1 capsule daily (l-Cystine, Serenoa repens, Cucurbita pepo, Pygeum africanum, vitamins, micronutrien | 24 weeks | Positive | 80 |
| None | -- | Positive | -- |
| varies by remedy and study | -- | Positive | -- |
| various dietary supplements (Nutrafol, apple extract, tocotrienols, pumpkin seed oil, Cistanche/Lami | -- | Positive | 1658 |
| Various non-prescription agents: procyanidin, cetirizine, caffeine, Oryza sativa bran, pumpkin seed | -- | Positive | -- |
| None | -- | Positive | -- |
| USPlus DERM (lipidosterolic extract of Serenoa repens) at 0.4 and 10 μg/mL in hair follicle organ cu | -- | Positive | -- |
Melhor horário: With meals to reduce gastrointestinal side effects
Safety & Side Effects
Efeitos Colaterais Relatados
- ⚠ Mild gastrointestinal upset (nausea, diarrhea)
- ⚠ Headache
- ⚠ Dizziness
- ⚠ Rare: decreased libido
Interações Conhecidas
- ● Anticoagulants and antiplatelet drugs (may increase bleeding risk)
- ● Oral contraceptives and hormone replacement therapy (anti-androgenic effects)
- ● Finasteride and dutasteride (additive 5-alpha-reductase inhibition)
Ingestão máxima tolerável: Not established
Consulte sempre o seu profissional de saúde antes de iniciar qualquer suplemento.Sempre consulte seu profissional de saúde antes de iniciar qualquer suplemento.
Frequently Asked Questions
Does Saw Palmetto help with Alopecia Androgenética?
Based on 22 studies with 2,123 participants, there is strong evidence from multiple clinical trials that Saw Palmetto may support Alopecia Androgenética management. Our evidence grade is A (Strong Evidence).
How much Saw Palmetto should I take for Alopecia Androgenética?
Studies have used various dosages. A commonly studied range is 320 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Saw Palmetto?
Reported side effects may include Mild gastrointestinal upset (nausea, diarrhea), Headache, Dizziness, Rare: decreased libido. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Saw Palmetto and Alopecia Androgenética?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 22 peer-reviewed studies with 2,123 total participants. The overall direction of effect is positive.
Related Evidence
Outros ingredientes para Alopecia Androgenética
Saw Palmetto para outras condições
Aviso Legal da FDA: Estas declarações não foram avaliadas pela Food and Drug Administration. Os produtos e informações neste site não se destinam a diagnosticar, tratar, curar ou prevenir qualquer doença. As notas de evidência apresentadas são baseadas em nossa análise de pesquisas revisadas por pares publicadas e não constituem aconselhamento médico. Sempre consulte seu profissional de saúde antes de iniciar qualquer regime de suplementação.