セレン：甲状腺関連脱毛症

合計10,466名の参加者を対象とした35件の研究（メタアナリシス6件、RCT 5件を含む）に基づく。研究間で結果にばらつきが見られる。

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結論

Despite selenium's role in thyroid function, research does not support supplementing with selenium to improve thyroid-related hair loss, and excess selenium may actually worsen hair problems.

Mixed results across 35 studies — no consistent benefit for hair loss
Selenium is important for thyroid health, but supplementation has not shown hair benefits
Selenium toxicity is a known cause of hair loss — excess intake is risky
Consult a healthcare provider before supplementing, especially for thyroid concerns

Key Study Findings

Observational Study n=2582

Relationship Between Serum Vitamins and Cognitive Impairment in the Elderly: A Study Based on the …

Dose: None vs: None Outcome: Cognitive impairment risk 効果: OR=0.695 (Vit D); OR=0.777 (FA) p=0.003 (Vit D); p=0.034 (FA)

対象集団: Elderly participants aged 60+ from NHANES 2011-2014

Systematic Review and Meta-Analysis n=7014

Trace Elements and Risk of Immune-Mediated Skin Disease: A Systematic Review and Meta-analysis.

Dose: None vs: Placebo 効果: Standardized mean differences reported for each element and disease combination (specific values not None

prospective controlled study n=30

Investigation of ischaemia-modified albumin and antioxidant vitamins and minerals levels in alopecia areata patients and …

Dose: None vs: Placebo 効果: None None

Review

The role of trace elements for the function and health of the skin.

Dose: None vs: Placebo 効果: None None

Review

Medical Marijuana and Treatment Personalization: The Role of Genetics and Epigenetics in Response to THC …

Dose: None vs: None Outcome: None 効果: None None

対象集団: Review of pharmacogenomics of THC and CBD

Review

Minerals and Trace Elements: Key Protectors of Skin Health and Defenders against Skin Disorders.

Dose: None vs: Placebo 効果: None None

Key Statistics

研究数

10748

参加者数

↔

Mixed

グレード

Referenced Papers

Relationship Between Serum Vitamins and Cognitive Impairment in the Elderly: A Study Based on the NHANES Database. Other

Brain and behavior 2026

Dietary supplementation of male mice with inorganic, organic or nanoparticle selenium preparations: evidence supporting a putative gut-thyroid-male fertility axis. Other

Redox report : … 2025 8 件の引用

Minerals and Trace Elements: Key Protectors of Skin Health and Defenders against Skin Disorders. Review

Current medicinal chemistry 2025 5 件の引用

The role of trace elements for the function and health of the skin. Review

Journal of trace … 2025 4 件の引用

Investigation of ischaemia-modified albumin and antioxidant vitamins and minerals levels in alopecia areata patients and evaluation of their relationship with … Other

Cutaneous and ocular … 2025 1 件の引用

Medical Marijuana and Treatment Personalization: The Role of Genetics and Epigenetics in Response to THC and CBD. Review

Genes 2025 1 件の引用

Trace Elements and Risk of Immune-Mediated Skin Disease: A Systematic Review and Meta-analysis. Meta-Analysis

Nutrition reviews 2025

A comprehensive investigation of biochemical status in patients with telogen effluvium: Analysis of Hb, ferritin, vitamin B12, vitamin D, thyroid … Other

Journal of cosmetic … 2024 7 件の引用

Micronutrients and Androgenetic Alopecia: A Systematic Review. Systematic Review

Molecular nutrition & … 2024 7 件の引用

Selenium in the supplement as the probable cause of hair loss and nail dystrophy. Other

Journal of cosmetic … 2024 4 件の引用

Cannabis-based medicines and medical cannabis for adults with cancer pain. Meta-Analysis

The Cochrane database … 2023 47 件の引用

Cautious Hope for Cannabidiol (CBD) in Rheumatology Care. Review

Arthritis care & … 2023 36 件の引用

Cannabidiol and brain function: current knowledge and future perspectives. Review

Frontiers in pharmacology 2023 29 件の引用

Medical and procedural treatment of androgenetic alopecia - Where are we? Review

Journal of the … 2023 20 件の引用

Bartter Syndrome: A Systematic Review of Case Reports and Case Series. Systematic Review

Medicina (Kaunas, Lithuania) 2023 17 件の引用

Hemp-Derived CBD Used in Food and Food Supplements. Review

Molecules (Basel, Switzerland) 2023 14 件の引用

Efficacy and tolerability of an oral supplement containing amino acids, iron, selenium, and marine hydrolyzed collagen in subjects with hair … RCT

Skin research and … 2023 11 件の引用

CANNabinoid Drug Interaction Review (CANN-DIR™). Review

Medical cannabis and … 2023 9 件の引用

Safety and risks of CBD oils purchased online: unveiling uncertain quality and vague health claims. Other

Frontiers in pharmacology 2023 8 件の引用

Oral supplementation in female telogen effluvium: a clinical and instrumental objective evidence of efficacy and tolerability of new oral cosmetic … Other

Italian journal of … 2023 3 件の引用

Effects of a Supplement Containing Cannabidiol (CBD) on Sedation and Ataxia Scores and Health. RCT

Journal of equine … 2022 6 件の引用

Acceptability of cannabidiol in patients with psychosis. Other

Therapeutic advances in … 2022 4 件の引用

A Review of Hemp as Food and Nutritional Supplement. Review

Cannabis and cannabinoid … 2021 171 件の引用

The Pharmacological Case for Cannabigerol. Review

The Journal of … 2021 162 件の引用

The Impact of Cannabidiol on Psychiatric and Medical Conditions. Review

Journal of clinical … 2020 42 件の引用

Alopecia Areata and Toxic Metals. Other

Skin appendage disorders 2020 10 件の引用

The Trouble with CBD Oil. Other

Medical cannabis and … 2018 158 件の引用

Nutritional Considerations for the Vegetarian and Vegan Dancer. Review

Journal of dance … 2018 15 件の引用

The Role of Micronutrients in Alopecia Areata: A Review. Review

American journal of … 2017 104 件の引用

Changes of serum trace elements level in patients with alopecia areata: A meta-analysis. Meta-Analysis

The Journal of … 2017 31 件の引用

Trichotillomania: Bizzare Patern of Hair Loss at 11-Year-old Girl. Case Report

Acta dermatovenerologica Croatica … 2016 6 件の引用

Vitamin B12 and omega-3 fatty acids together regulate lipid metabolism in Wistar rats. Other

Prostaglandins, leukotrienes, and … 2015 40 件の引用

[Vitamins and nutritional supplements in older persons: How to diagnose and when to substitute?]. Review

Der Internist 2015 3 件の引用

Micronutrient deficiencies in inflammatory bowel disease: from A to zinc. Review

Inflammatory bowel diseases 2012 224 件の引用

[Nutrition and fertility]. Other

Medycyna wieku rozwojowego 2011

A high prevalence of biochemical evidence of vitamin B12 or folate deficiency does not translate into a comparable prevalence of … Review

Food and nutrition … 2008 83 件の引用

Vitamin B12, folic acid, and the prevention of dementia. Other

The New England … 2006 47 件の引用

Oxidative stress in aldosteronism. Review

Cardiovascular research 2006 42 件の引用

Element concentrations in serum, erythrocytes, hair and urine of alopecia patients. Other

Acta dermato-venereologica 1986 53 件の引用

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

一般的な使用量

general:: 55 mcg/day

上限量： 400 mcg/day

研究で検討された用量

用量	期間	効果	N
None	--	Positive	2582
None	--	Mixed	7014
None	--	Neutral	30
None	--	Mixed	--
None	--	Mixed	--
None	--	Positive	--
NaSe 5.6ppm, Met 4.7ppm, DPDS 14.2ppm, NanoSe 2.7ppm	4 weeks	Positive	40
not applicable	--	Mixed	180

推奨摂取タイミング： With meals for better absorption

Safety & Side Effects

報告されている副作用

⚠ Hair loss at excessive doses (selenosis)
⚠ Brittle nails
⚠ Garlic-like breath odor at high doses
⚠ Nausea and diarrhea

既知の相互作用

● Statins (selenium may reduce statin effectiveness)
● Chemotherapy drugs (antioxidant effects may theoretically interfere)
● Niacin (may decrease HDL-raising effect when combined)

耐容上限摂取量： 400 mcg/day

サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。

Frequently Asked Questions

Does セレン help with 甲状腺関連脱毛症?

Based on 38 studies with 10,748 participants, there is strong evidence from multiple clinical trials that セレン may support 甲状腺関連脱毛症 management. Our evidence grade is A (Strong Evidence).

How much セレン should I take for 甲状腺関連脱毛症?

Studies have used various dosages. A commonly studied range is 55 mcg/day. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of セレン?

Reported side effects may include Hair loss at excessive doses (selenosis), Brittle nails, Garlic-like breath odor at high doses, Nausea and diarrhea. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for セレン and 甲状腺関連脱毛症?

We rate the evidence as Grade A (Strong Evidence). This rating is based on 38 peer-reviewed studies with 10,748 total participants. The overall direction of effect is mixed.

Related Evidence

セレン他の症状・状態について

栄養不足による脱毛症 A

総合評価

合計10,466名の参加者を対象とした35件の研究（メタアナリシス6件、RCT 5件を含む）に基づく。研究間で結果にばらつきが見られる。

Evidence Strength92%

High confidence

研究の内訳

RCT (2)Meta (3)Other (33)

代替成分との比較

この症状に対する他の成分との比較をご覧ください。

に関するすべての成分を見る：甲状腺関連脱毛症

詳しく見る

FDAに関する免責事項: これらの記述は米国食品医薬品局（FDA）による評価を受けていません。本ウェブサイトの製品および情報は、疾病の診断、治療、治癒、または予防を目的としたものではありません。表示されているエビデンスグレードは、公開された査読済み研究の分析に基づいており、医療上の助言を構成するものではありません。サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。

セレン ： 甲状腺関連脱毛症

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結論

Key Study Findings

Key Statistics

Referenced Papers

Dosage & Usage

一般的な使用量

研究で検討された用量

Safety & Side Effects

報告されている副作用

既知の相互作用

Frequently Asked Questions

Related Evidence

セレン 他の症状・状態について

セレン：甲状腺関連脱毛症

セレン他の症状・状態について