Biotin untuk Telogen Effluvium

Q: Does Biotin help with Telogen Effluvium?

Based on 9 studies with 484 participants, there is moderate evidence from clinical studies that Biotin may support Telogen Effluvium management. Our evidence grade is B (Good Evidence).

Q: How much Biotin should I take for Telogen Effluvium?

Studies have used various dosages. A commonly studied range is 30 mcg/day. Always consult your healthcare provider before starting any supplement regimen.

Q: Are there side effects of Biotin?

Reported side effects may include May interfere with laboratory test results (troponin, thyroid panels), Rare skin rashes at high doses, Mild gastrointestinal discomfort, Potential acne breakouts at doses above 5,000 mcg. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

Q: How strong is the evidence for Biotin and Telogen Effluvium?

We rate the evidence as Grade B (Good Evidence). This rating is based on 9 peer-reviewed studies with 484 total participants. The overall direction of effect is mixed.

Berdasarkan 9 studi (2 RCTs) dengan 484 peserta secara total. Hasil bervariasi di antara studi-studi tersebut.

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Kesimpulan

Research on biotin for telogen effluvium is mixed — it may help in some cases, especially if biotin levels are low, but it is not a reliable standalone solution for this type of hair shedding.

Results are mixed across 9 studies — some show benefit, others do not
Lower serum biotin levels have been observed in some telogen effluvium patients
Biotin was often studied as part of multi-ingredient supplements, making it hard to isolate its specific effect
Testing biotin levels before supplementing may help identify who is most likely to benefit

Key Study Findings

Review

Safety First: A Comprehensive Review of Nutritional Supplements for Hair Loss in Breast Cancer Patients.

Dose: None vs: Placebo Efek: None None

narrative review

Addressing the Root Causes of Female Hair Loss and Non-Pharmaceutical Interventions.

Dose: None vs: Placebo Efek: None None

RCT n=80 24 weeks Double-blind

Oral Supplementation with l-Cystine, Serenoa repens, Cucurbita pepo, and Pygeum africanum in Chronic Telogen Effluvium …

Dose: 1 capsule daily (l-Cystine, Serenoa repens, Cucurbita pepo, Pygeum africanum, vitamins, micronutrien vs: Placebo Efek: MD=+12.3 hairs/cm2 at 6 months p<0.05

case-control study n=180

A comprehensive investigation of biochemical status in patients with telogen effluvium: Analysis of Hb, ferritin, …

Dose: not applicable vs: Placebo Efek: None None

narrative review

Valproate-associated hair abnormalities: Pathophysiology and management strategies.

Dose: not specified vs: Placebo Efek: None None

case-control study n=80

Biotin Deficiency in Telogen Effluvium: Fact or Fiction?

Dose: None vs: Placebo Efek: None None

Key Statistics

Studi

484

Peserta

↔

Mixed

Peringkat

Referenced Papers

Oral Supplementation with l-Cystine, Serenoa repens, Cucurbita pepo, and Pygeum africanum in Chronic Telogen Effluvium and Androgenetic Alopecia: A Double-Blind, … Other

Skin appendage disorders 2025 3 sitasi

Safety First: A Comprehensive Review of Nutritional Supplements for Hair Loss in Breast Cancer Patients. Review

Nutrients 2025 2 sitasi

Addressing the Root Causes of Female Hair Loss and Non-Pharmaceutical Interventions. Review

Journal of drugs … 2025

A comprehensive investigation of biochemical status in patients with telogen effluvium: Analysis of Hb, ferritin, vitamin B12, vitamin D, thyroid … Other

Journal of cosmetic … 2024 7 sitasi

Valproate-associated hair abnormalities: Pathophysiology and management strategies. Review

Human psychopharmacology 2022 7 sitasi

Biotin Deficiency in Telogen Effluvium: Fact or Fiction? Other

The Journal of … 2020 7 sitasi

Comparative evaluation between two nutritional supplements in the improvement of telogen effluvium. Other

Clinical, cosmetic and … 2018 16 sitasi

Cystine-thiamin-containing hair-growth formulation modulates the response to UV radiation in an in vitro model for growth-limiting conditions of human keratinocytes. Other

Journal of photochemistry … 2018 16 sitasi

Serum Biotin Levels in Women Complaining of Hair Loss. Other

International journal of … 2016 89 sitasi

Use of Vitamins and Minerals in the Treatment of Hair Loss: A Cross-Sectional Survey among Dermatologists in Saudi Arabia. Other

Journal of cutaneous … 2014 10 sitasi

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosis yang Umum Digunakan

general:: 30 mcg/day
hairloss:: 2,500-5,000 mcg/day

Batas atas: No established UL (water-soluble)

Dosis yang Diteliti dalam Penelitian

Dosis	Durasi	Efek	N
None	--	Mixed	--
None	--	Positive	--
1 capsule daily (l-Cystine, Serenoa repens, Cucurbita pepo, Pygeum africanum, vitamins, micronutrien	24 weeks	Positive	80
not applicable	--	Mixed	180
not specified	--	Positive	--
None	--	Neutral	80
recommended daily intake amounts; taken orally for 180 days	26 weeks	Positive	--
None	--	Neutral	144

Waktu terbaik diminum: With meals for better absorption

Safety & Side Effects

Efek Samping yang Dilaporkan

⚠ May interfere with laboratory test results (troponin, thyroid panels)
⚠ Rare skin rashes at high doses
⚠ Mild gastrointestinal discomfort
⚠ Potential acne breakouts at doses above 5,000 mcg

Interaksi yang Diketahui

● Anticonvulsants (carbamazepine, phenytoin) may reduce biotin levels
● Raw egg whites (avidin) bind biotin and reduce absorption
● Prolonged antibiotic use may deplete gut bacterial biotin synthesis

Asupan atas yang dapat ditoleransi: No established UL (water-soluble)

Selalu konsultasikan dengan tenaga kesehatan Anda sebelum memulai suplemen apa pun.Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai suplemen apa pun.

Frequently Asked Questions

Does Biotin help with Telogen Effluvium?

Based on 9 studies with 484 participants, there is moderate evidence from clinical studies that Biotin may support Telogen Effluvium management. Our evidence grade is B (Good Evidence).

How much Biotin should I take for Telogen Effluvium?

Studies have used various dosages. A commonly studied range is 30 mcg/day. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Biotin?

Reported side effects may include May interfere with laboratory test results (troponin, thyroid panels), Rare skin rashes at high doses, Mild gastrointestinal discomfort, Potential acne breakouts at doses above 5,000 mcg. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Biotin and Telogen Effluvium?

We rate the evidence as Grade B (Good Evidence). This rating is based on 9 peer-reviewed studies with 484 total participants. The overall direction of effect is mixed.

Related Evidence

Bahan lain untuk Telogen Effluvium

Minoxidil A Minyak Biji Hitam A Viviscal A Zat Besi B Keratin B Asam Lemak Omega-3 B

Biotin untuk kondisi lain

Kerontokan Rambut Akibat Defisiensi Nutrisi B

Kesimpulan Singkat

Berdasarkan 9 studi (2 RCTs) dengan 484 peserta secara total. Hasil bervariasi di antara studi-studi tersebut.

Evidence Strength72%

High confidence

Rincian Studi

RCT (0)Meta (0)Other (9)

Bandingkan Alternatif

Lihat bagaimana bahan lain dibandingkan untuk kondisi ini.

Lihat semua bahan untuk Telogen Effluvium

Pelajari Lebih Lanjut

Penafian FDA: Pernyataan-pernyataan ini belum dievaluasi oleh Food and Drug Administration. Produk dan informasi di situs web ini tidak dimaksudkan untuk mendiagnosis, mengobati, menyembuhkan, atau mencegah penyakit apa pun. Peringkat bukti yang disajikan didasarkan pada analisis kami terhadap penelitian yang ditinjau sejawat dan tidak merupakan saran medis. Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai regimen suplemen apa pun.