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Zinc pour Telogen Effluvium

F

Basé sur 29 études (3 RCTs) avec 30,246 participants au total. Les résultats sont mitigés entre les études.

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F

En conclusion

Moderate evidence suggests that zinc deficiency may contribute to telogen effluvium, and supplementation may help if levels are low — but routine zinc supplementation for hair shedding is not clearly supported.

  • Lower zinc levels are frequently found in telogen effluvium patients
  • Some RCTs show benefits from zinc-containing supplement combinations
  • Difficult to isolate zinc's specific effect from multi-ingredient formulas
  • Testing zinc levels and supplementing only if deficient is a reasonable approach

Key Study Findings

Prospective Open-Label Interventional Study n=343 4 weeks Open-label
Effect of a Hydrolyzed Collagen, Vitamin, and Zinc Containing Nutritional Supplement on Telogen Effluvium.
Dose: Pilopeptan Intensive (hydrolyzed collagen, Group B vitamins, zinc); daily for 1 month vs: Placebo Effet: Significant improvements in all hair parameters at T1 and T2 (P < 0.001) p<0.001
Retrospective Cross-Sectional Study n=23975
Hair Loss and Zinc Deficiency: A Cross-Sectional Study.
Dose: None vs: Placebo Effet: Median zinc 96 µg/dL (hair loss) vs 99 µg/dL (control); statistically significant but clinically min p<0.001
cross-sectional study
Zinc Status in Kurdish Adults With Hair Loss.
Dose: None vs: Placebo Effet: None None
Case-Control Study n=100
Role of zinc in chronic telogen effluvium in serum and hair of patients with alopecia.
Dose: None vs: Placebo Effet: None 0.05

Key Statistics

32

Études

30246

Participants

Mixed

F

Note

Referenced Papers

Healthcare (Basel, Switzerland) 2025
Journal of drugs … 2021 3 citations
Acta dermatovenerologica Croatica … 2016 6 citations
Annals of dermatology 2013 114 citations
Dermatologic therapy 2012 31 citations
American journal of … 2005 140 citations

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Posologies couramment utilisées

general:
8-11 mg/day
hairloss:
15-30 mg/day

Limite supérieure : 40 mg/day

Posologies étudiées dans la recherche

Posologie Durée Effet N
Pilopeptan Intensive (hydrolyzed collagen, Group B vitamins, zinc); daily for 1 month 4 weeks Positive 343
None -- Neutral 23975
None -- Neutral --
None -- Negative 100
not applicable -- Mixed 180
None -- Mixed 100
None -- Mixed --
4 tablets daily (arginine, l-cystine, zinc, vitamin B6) 12 weeks Positive 20

Moment optimal de prise : With meals to minimize stomach upset; separate from iron and calcium by 2 hours

Safety & Side Effects

Effets indésirables signalés

  • Nausea and vomiting (especially on an empty stomach)
  • Metallic taste in the mouth
  • Copper depletion with chronic high-dose use
  • Headache and diarrhea

Interactions connues

  • Copper supplements (zinc inhibits copper absorption at doses >40 mg/day)
  • Tetracycline and quinolone antibiotics (mutual absorption reduction)
  • Penicillamine (zinc reduces absorption of this rheumatoid arthritis drug)

Apport maximal tolérable : 40 mg/day

Consultez toujours votre professionnel de santé avant de commencer tout complément alimentaire.Consultez toujours votre professionnel de santé avant de commencer tout complément alimentaire.

Frequently Asked Questions

Does Zinc help with Telogen Effluvium?
Based on 32 studies with 30,246 participants, there is insufficient evidence at this time that Zinc may support Telogen Effluvium management. Our evidence grade is F (Evidence Against).
How much Zinc should I take for Telogen Effluvium?
Studies have used various dosages. A commonly studied range is 8-11 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Zinc?
Reported side effects may include Nausea and vomiting (especially on an empty stomach), Metallic taste in the mouth, Copper depletion with chronic high-dose use, Headache and diarrhea. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Zinc and Telogen Effluvium?
We rate the evidence as Grade F (Evidence Against). This rating is based on 32 peer-reviewed studies with 30,246 total participants. The overall direction of effect is mixed.

Related Evidence

Avertissement FDA: Ces déclarations n'ont pas été évaluées par la Food and Drug Administration. Les produits et informations sur ce site ne sont pas destinés à diagnostiquer, traiter, guérir ou prévenir quelque maladie que ce soit. Les notes de preuve présentées sont basées sur notre analyse de la recherche publiée et évaluée par des pairs et ne constituent pas un avis médical. Consultez toujours votre professionnel de santé avant de commencer tout régime de compléments alimentaires.