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Biotin pour Telogen Effluvium

B

Basé sur 9 études (2 RCTs) avec 484 participants au total. Les résultats sont mitigés entre les études.

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B

En conclusion

Research on biotin for telogen effluvium is mixed — it may help in some cases, especially if biotin levels are low, but it is not a reliable standalone solution for this type of hair shedding.

  • Results are mixed across 9 studies — some show benefit, others do not
  • Lower serum biotin levels have been observed in some telogen effluvium patients
  • Biotin was often studied as part of multi-ingredient supplements, making it hard to isolate its specific effect
  • Testing biotin levels before supplementing may help identify who is most likely to benefit

Key Study Findings

RCT n=80 24 weeks Double-blind
Oral Supplementation with l-Cystine, Serenoa repens, Cucurbita pepo, and Pygeum africanum in Chronic Telogen Effluvium …
Dose: 1 capsule daily (l-Cystine, Serenoa repens, Cucurbita pepo, Pygeum africanum, vitamins, micronutrien vs: Placebo Effet: MD=+12.3 hairs/cm2 at 6 months p<0.05
narrative review
Valproate-associated hair abnormalities: Pathophysiology and management strategies.
Dose: not specified vs: Placebo Effet: None None
case-control study n=80
Biotin Deficiency in Telogen Effluvium: Fact or Fiction?
Dose: None vs: Placebo Effet: None None

Key Statistics

9

Études

484

Participants

Mixed

B

Note

Referenced Papers

The Journal of … 2020 7 citations
International journal of … 2016 89 citations

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Posologies couramment utilisées

general:
30 mcg/day
hairloss:
2,500-5,000 mcg/day

Limite supérieure : No established UL (water-soluble)

Posologies étudiées dans la recherche

Posologie Durée Effet N
None -- Mixed --
None -- Positive --
1 capsule daily (l-Cystine, Serenoa repens, Cucurbita pepo, Pygeum africanum, vitamins, micronutrien 24 weeks Positive 80
not applicable -- Mixed 180
not specified -- Positive --
None -- Neutral 80
recommended daily intake amounts; taken orally for 180 days 26 weeks Positive --
None -- Neutral 144

Moment optimal de prise : With meals for better absorption

Safety & Side Effects

Effets indésirables signalés

  • May interfere with laboratory test results (troponin, thyroid panels)
  • Rare skin rashes at high doses
  • Mild gastrointestinal discomfort
  • Potential acne breakouts at doses above 5,000 mcg

Interactions connues

  • Anticonvulsants (carbamazepine, phenytoin) may reduce biotin levels
  • Raw egg whites (avidin) bind biotin and reduce absorption
  • Prolonged antibiotic use may deplete gut bacterial biotin synthesis

Apport maximal tolérable : No established UL (water-soluble)

Consultez toujours votre professionnel de santé avant de commencer tout complément alimentaire.Consultez toujours votre professionnel de santé avant de commencer tout complément alimentaire.

Frequently Asked Questions

Does Biotin help with Telogen Effluvium?
Based on 9 studies with 484 participants, there is moderate evidence from clinical studies that Biotin may support Telogen Effluvium management. Our evidence grade is B (Good Evidence).
How much Biotin should I take for Telogen Effluvium?
Studies have used various dosages. A commonly studied range is 30 mcg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Biotin?
Reported side effects may include May interfere with laboratory test results (troponin, thyroid panels), Rare skin rashes at high doses, Mild gastrointestinal discomfort, Potential acne breakouts at doses above 5,000 mcg. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Biotin and Telogen Effluvium?
We rate the evidence as Grade B (Good Evidence). This rating is based on 9 peer-reviewed studies with 484 total participants. The overall direction of effect is mixed.

Related Evidence

Avertissement FDA: Ces déclarations n'ont pas été évaluées par la Food and Drug Administration. Les produits et informations sur ce site ne sont pas destinés à diagnostiquer, traiter, guérir ou prévenir quelque maladie que ce soit. Les notes de preuve présentées sont basées sur notre analyse de la recherche publiée et évaluée par des pairs et ne constituent pas un avis médical. Consultez toujours votre professionnel de santé avant de commencer tout régime de compléments alimentaires.