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Keratin for Telogen Effluvium

B

Based on 11 studies (1 meta-analysis, 1 RCT) with 61 total participants. 6/11 studies show positive effects.

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B

The Bottom Line

Research does not support keratin supplementation as helpful for telogen effluvium — the limited evidence available suggests it is unlikely to meaningfully reduce this type of hair shedding.

  • Majority of studies show negative or no effects for keratin in telogen effluvium
  • Very small participant pool (60 people) limits the reliability of findings
  • Telogen effluvium has different underlying mechanisms than age-related thinning, where keratin shows more promise
  • Other approaches may be more effective for addressing telogen effluvium specifically

Key Study Findings

Case Reports n=1 Open-label
Plica Neuropathica (Polonica) Secondary to Diffuse Alopecia: A Case Report and Literature Review.
Dose: None vs: None Outcome: None Effect: None None

Population: 62-year-old female with diffuse alopecia and plica neuropathica

Systematic Review
Regenerative medicine in the treatment of specific dermatologic disorders: a systematic review of randomized controlled …
Dose: Various regenerative methods vs: Standard treatment or placebo Outcome: Dermatologic disease improvement Effect: None None

Population: Patients with specific dermatologic diseases

Review
The Role of One-Carbon Metabolism in Healthy Brain Aging.
Dose: None vs: None Outcome: folate status Effect: None None

Population: None

Review
Regenerative medicine strategies for hair growth and regeneration: A narrative review of literature.
Dose: None vs: None Outcome: Hair regrowth Effect: None None

Population: Alopecia patients

Other
Reply to "Vitamin D status in scarring and nonscarring alopecia".
Dose: None vs: None Outcome: None Effect: None None

Population: None

Review
Role of vitamin D in hair loss: A short review.
Dose: None vs: Placebo Effect: None None

Key Statistics

11

Studies

61

Participants

Positive

B

Grade

Referenced Papers

Journal of cosmetic … 2021 44 citations

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Commonly Used Dosages

hairloss:
500 mg/day

Upper limit: Not established

Dosages Studied in Research

Dosage Duration Effect N
None -- Mixed 1
Various regenerative methods -- Positive --
None -- Positive --
None -- Positive --
None -- Mixed --
None -- Negative --
not applicable (genetic association study) -- Negative 60
recommended daily intake amounts; taken orally for 180 days 26 weeks Positive --

Best taken: With meals for better absorption

Safety & Side Effects

Reported Side Effects

  • Generally well tolerated
  • Mild gastrointestinal discomfort in some individuals
  • Rare allergic reactions

Known Interactions

  • No significant drug interactions established
  • May interact with protein absorption in individuals with digestive disorders

Tolerable upper intake: Not established

Always consult your healthcare provider before starting any supplement.

Frequently Asked Questions

Does Keratin help with Telogen Effluvium?
Based on 11 studies with 61 participants, there is moderate evidence from clinical studies that Keratin may support Telogen Effluvium management. Our evidence grade is B (Good Evidence).
How much Keratin should I take for Telogen Effluvium?
Studies have used various dosages. A commonly studied range is 500 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Keratin?
Reported side effects may include Generally well tolerated, Mild gastrointestinal discomfort in some individuals, Rare allergic reactions. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Keratin and Telogen Effluvium?
We rate the evidence as Grade B (Good Evidence). This rating is based on 11 peer-reviewed studies with 61 total participants. The overall direction of effect is positive.

Related Evidence

FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The products and information on this website are not intended to diagnose, treat, cure, or prevent any disease. The evidence grades presented are based on our analysis of published peer-reviewed research and do not constitute medical advice. Always consult your healthcare provider before starting any supplement regimen.