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Aceite de Semilla de Calabaza para Alopecia Androgenética

A

Basado en 14 estudios (2 meta-analyses, 3 RCTs) con 1,874 participantes en total. 13/14 estudios muestran efectos positivos.

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A

Conclusión

Pumpkin seed oil is well-supported by multiple clinical trials as a natural supplement that may help promote hair growth in androgenetic alopecia through its DHT-blocking properties.

  • 13 out of 14 studies show positive effects, including 3 RCTs
  • Acts as a natural 5-alpha reductase inhibitor, potentially reducing DHT levels
  • Both oral supplementation and topical application have been studied
  • One RCT showed comparable results to minoxidil 5% in women

Key Study Findings

narrative review
Addressing the Root Causes of Female Hair Loss and Non-Pharmaceutical Interventions.
Dose: None vs: Placebo Efecto: None None
RCT n=80 24 weeks Double-blind
Oral Supplementation with l-Cystine, Serenoa repens, Cucurbita pepo, and Pygeum africanum in Chronic Telogen Effluvium …
Dose: 1 capsule daily (l-Cystine, Serenoa repens, Cucurbita pepo, Pygeum africanum, vitamins, micronutrien vs: Placebo Efecto: MD=+12.3 hairs/cm2 at 6 months p<0.05
narrative review
Herbal Remedies for Hair Loss: A Review of Efficacy and Safety.
Dose: varies by remedy and study vs: Placebo Efecto: None None
systematic review n=1658 Double-blind
Effects of dietary supplements on androgenetic alopecia: a systematic review and network meta-analysis.
Dose: various dietary supplements (Nutrafol, apple extract, tocotrienols, pumpkin seed oil, Cistanche/Lami vs: Placebo Efecto: None None
review Single-blind
Do Non-Prescription Products Help in Managing Androgenic Alopecia?
Dose: Various non-prescription agents: procyanidin, cetirizine, caffeine, Oryza sativa bran, pumpkin seed vs: Placebo Efecto: Considerable improvements in one or more parameters across 13 included studies None
review
Emerging and traditional 5-α reductase inhibitors and androgen receptor antagonists for male androgenetic alopecia.
Dose: finasteride 1 mg/day; dutasteride 0.5 mg/day; various natural product doses vs: Placebo Efecto: None None

Key Statistics

15

Estudios

1874

Participantes

Positive

A

Calificación

Referenced Papers

Skin appendage disorders 2025 7 citas
Dermatologic therapy 2022 41 citas
Archives of dermatological … 2020 51 citas
Journal of cosmetic … 2019 100 citas

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosificaciones de uso común

hairloss:
400 mg/day

Límite superior: Not established

Dosificaciones estudiadas en la investigación

Dosificación Duración Efecto N
None -- Positive --
1 capsule daily (l-Cystine, Serenoa repens, Cucurbita pepo, Pygeum africanum, vitamins, micronutrien 24 weeks Positive 80
varies by remedy and study -- Positive --
various dietary supplements (Nutrafol, apple extract, tocotrienols, pumpkin seed oil, Cistanche/Lami -- Positive 1658
Various non-prescription agents: procyanidin, cetirizine, caffeine, Oryza sativa bran, pumpkin seed -- Positive --
finasteride 1 mg/day; dutasteride 0.5 mg/day; various natural product doses -- Positive --
various CAMs: pumpkin seed oil, saw palmetto, melatonin extract, caffeine extract, rosemary oil -- Positive --
not specified -- Positive --

Mejor momento para tomar: With meals for better absorption

Safety & Side Effects

Efectos secundarios reportados

  • Mild gastrointestinal upset
  • Possible stomach discomfort at high doses
  • Rare allergic reactions in individuals with cucurbit allergies

Interacciones conocidas

  • Anticoagulants (theoretical increased bleeding risk)
  • Lithium (pumpkin seed oil may have diuretic properties)

Ingesta máxima tolerable: Not established

Consulte siempre a su profesional de salud antes de comenzar cualquier suplemento.Siempre consulte a su profesional de salud antes de comenzar cualquier suplemento.

Frequently Asked Questions

Does Aceite de Semilla de Calabaza help with Alopecia Androgenética?
Based on 15 studies with 1,874 participants, there is strong evidence from multiple clinical trials that Aceite de Semilla de Calabaza may support Alopecia Androgenética management. Our evidence grade is A (Strong Evidence).
How much Aceite de Semilla de Calabaza should I take for Alopecia Androgenética?
Studies have used various dosages. A commonly studied range is 400 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Aceite de Semilla de Calabaza?
Reported side effects may include Mild gastrointestinal upset, Possible stomach discomfort at high doses, Rare allergic reactions in individuals with cucurbit allergies. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Aceite de Semilla de Calabaza and Alopecia Androgenética?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 15 peer-reviewed studies with 1,874 total participants. The overall direction of effect is positive.

Related Evidence

Aviso legal FDA: Estas declaraciones no han sido evaluadas por la Food and Drug Administration. Los productos y la información en este sitio web no están destinados a diagnosticar, tratar, curar ni prevenir ninguna enfermedad. Las calificaciones de evidencia presentadas se basan en nuestro análisis de investigación publicada revisada por pares y no constituyen consejo médico. Siempre consulte a su profesional de salud antes de comenzar cualquier régimen de suplementos.