فيتامين B12 لـ تساقط الشعر بسبب نقص التغذية
Fبناءً على 20 دراسة بمشاركة 8,355 مشاركًا إجمالاً. النتائج متباينة بين الدراسات.
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الخلاصة
Research shows mixed results for vitamin B12 and hair loss — while deficiency may contribute to hair thinning, supplementation is unlikely to help unless you have a confirmed B12 deficiency.
- Mixed results across 20 studies — no consistent benefit from supplementation
- Some studies find lower B12 levels in hair loss patients, others do not
- No large-scale RCTs testing B12 supplementation specifically for hair regrowth
- Supplementation may only help if a genuine B12 deficiency is present
Key Study Findings
retrospective observational
n=113
Telogen Effluvium Following Coronavirus Disease-2019 Infection: A Retrospective Study of 113 Cases.
Dose: None
مقابل: Placebo
التأثير: None
None
Retrospective cohort
n=2851
Retrospective Review of 2851 Female Patients With Telogen Effluvium: A Single-Center Experience.
Dose: None
مقابل: Placebo
التأثير: Ferritin low in 46.5% of patients; iron deficiency in 29.5%
p<0.05
Review
Medical Marijuana and Treatment Personalization: The Role of Genetics and Epigenetics in Response to THC …
Dose: None
مقابل: None
Outcome: None
التأثير: None
None
المجتمع المدروس: Review of pharmacogenomics of THC and CBD
case-control study
n=180
A comprehensive investigation of biochemical status in patients with telogen effluvium: Analysis of Hb, ferritin, …
Dose: not applicable
مقابل: Placebo
التأثير: None
None
Cross-Sectional Study
n=108
Evaluation of the relationship of digital phototrichogram findings of patients with diffuse hair loss with …
Dose: None
مقابل: Placebo
التأثير: None
0.05
Case-control
n=973
Micronutrient Deficiencies and Digital Computerized Phototrichogram Analysis in Telogen Effluvium: a Retrospective Correlation Study in …
Dose: None
مقابل: Placebo
التأثير: r=0.417 (HGB and AHR in females)
p=0.008
Key Statistics
19
الدراسات
8130
المشاركون
↔
Mixed
F
التقييم
Referenced Papers
Retrospective Review of 2851 Female Patients With Telogen Effluvium: A Single-Center Experience.
Other
Journal of cosmetic …
2025
4 اقتباسات
Genes
2025
1 اقتباسات
Telogen Effluvium Following Coronavirus Disease-2019 Infection: A Retrospective Study of 113 Cases.
Other
International journal of …
2025
Journal of cosmetic …
2024
7 اقتباسات
Northern clinics of …
2024
1 اقتباسات
JAMA
2023
49 اقتباسات
Dermatology practical & …
2023
4 اقتباسات
Sports medicine - …
2022
34 اقتباسات
Frontiers in pharmacology
2022
31 اقتباسات
Journal of cosmetic …
2022
22 اقتباسات
Turkish journal of …
2022
8 اقتباسات
Journal of pain …
2020
56 اقتباسات
NonScarring Diffuse Hair Loss in Women: a Clinico-Etiological Study from tertiary care center in North-West India.
Observational
Journal of cosmetic …
2019
25 اقتباسات
American journal of …
2017
104 اقتباسات
Journal of drugs …
2016
56 اقتباسات
Dermatology research and …
2016
26 اقتباسات
Acta dermatovenerologica Croatica …
2016
6 اقتباسات
Prostaglandins, leukotrienes, and …
2015
40 اقتباسات
Clinical and experimental …
2009
34 اقتباسات
Dermatologic clinics
1993
38 اقتباسات
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
الجرعات الشائعة
- general:
- 2.4 mcg/day
- deficiency:
- 1,000-2,000 mcg/day
الحد الأعلى: No established UL
الجرعات المدروسة في الأبحاث
| الجرعة | المدة | التأثير | ن |
|---|---|---|---|
| None | -- | Neutral | 113 |
| None | -- | Neutral | 2851 |
| None | -- | Mixed | -- |
| not applicable | -- | Mixed | 180 |
| None | -- | Mixed | 108 |
| None | -- | Positive | 973 |
| None | -- | Neutral | -- |
| 300 mg single dose | -- | Mixed | 9 |
أفضل وقت للتناول: With meals; sublingual form can be taken any time
Safety & Side Effects
الآثار الجانبية المُبلّغ عنها
- ⚠ Generally well tolerated even at high doses
- ⚠ Rare allergic reactions (itching, swelling)
- ⚠ Mild diarrhea or nausea at very high doses
التفاعلات المعروفة
- ● Metformin (reduces B12 absorption by 10-30%)
- ● Proton pump inhibitors and H2 blockers (reduce B12 absorption)
- ● Colchicine (may reduce B12 absorption)
الحد الأقصى المسموح به: No established UL
استشر مقدم الرعاية الصحية دائماً قبل البدء بأي مكمل غذائي.
Frequently Asked Questions
Does فيتامين B12 help with تساقط الشعر بسبب نقص التغذية?
Based on 19 studies with 8,130 participants, there is insufficient evidence at this time that فيتامين B12 may support تساقط الشعر بسبب نقص التغذية management. Our evidence grade is F (Evidence Against).
How much فيتامين B12 should I take for تساقط الشعر بسبب نقص التغذية?
Studies have used various dosages. A commonly studied range is 2.4 mcg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of فيتامين B12?
Reported side effects may include Generally well tolerated even at high doses, Rare allergic reactions (itching, swelling), Mild diarrhea or nausea at very high doses. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for فيتامين B12 and تساقط الشعر بسبب نقص التغذية?
We rate the evidence as Grade F (Evidence Against). This rating is based on 19 peer-reviewed studies with 8,130 total participants. The overall direction of effect is mixed.
Related Evidence
مكونات أخرى لـ تساقط الشعر بسبب نقص التغذية
فيتامين B12 لحالات أخرى
إخلاء مسؤولية FDA: لم تُقيَّم هذه البيانات من قبل إدارة الغذاء والدواء (FDA). لا تهدف المنتجات والمعلومات الواردة في هذا الموقع إلى تشخيص أو علاج أو شفاء أو الوقاية من أي مرض. تستند تقييمات الأدلة المعروضة إلى تحليلنا للأبحاث المحكّمة المنشورة ولا تُشكّل نصيحة طبية. استشر مقدم الرعاية الصحية دائماً قبل البدء بأي نظام مكملات.