السيلينيوم لـ تساقط الشعر المرتبط بالغدة الدرقية

بناءً على 35 دراسة (6 meta-analyses, 5 RCTs) بمشاركة 10,466 مشاركًا إجمالاً. النتائج متباينة بين الدراسات.

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الخلاصة

Despite selenium's role in thyroid function, research does not support supplementing with selenium to improve thyroid-related hair loss, and excess selenium may actually worsen hair problems.

Mixed results across 35 studies — no consistent benefit for hair loss
Selenium is important for thyroid health, but supplementation has not shown hair benefits
Selenium toxicity is a known cause of hair loss — excess intake is risky
Consult a healthcare provider before supplementing, especially for thyroid concerns

Key Study Findings

Observational Study n=2582

Relationship Between Serum Vitamins and Cognitive Impairment in the Elderly: A Study Based on the …

Dose: None مقابل: None Outcome: Cognitive impairment risk التأثير: OR=0.695 (Vit D); OR=0.777 (FA) p=0.003 (Vit D); p=0.034 (FA)

المجتمع المدروس: Elderly participants aged 60+ from NHANES 2011-2014

Systematic Review and Meta-Analysis n=7014

Trace Elements and Risk of Immune-Mediated Skin Disease: A Systematic Review and Meta-analysis.

Dose: None مقابل: Placebo التأثير: Standardized mean differences reported for each element and disease combination (specific values not None

prospective controlled study n=30

Investigation of ischaemia-modified albumin and antioxidant vitamins and minerals levels in alopecia areata patients and …

Dose: None مقابل: Placebo التأثير: None None

Review

The role of trace elements for the function and health of the skin.

Dose: None مقابل: Placebo التأثير: None None

Review

Medical Marijuana and Treatment Personalization: The Role of Genetics and Epigenetics in Response to THC …

Dose: None مقابل: None Outcome: None التأثير: None None

المجتمع المدروس: Review of pharmacogenomics of THC and CBD

Review

Minerals and Trace Elements: Key Protectors of Skin Health and Defenders against Skin Disorders.

Dose: None مقابل: Placebo التأثير: None None

Key Statistics

الدراسات

10748

المشاركون

↔

Mixed

التقييم

Referenced Papers

Relationship Between Serum Vitamins and Cognitive Impairment in the Elderly: A Study Based on the NHANES Database. Other

Brain and behavior 2026

Dietary supplementation of male mice with inorganic, organic or nanoparticle selenium preparations: evidence supporting a putative gut-thyroid-male fertility axis. Other

Redox report : … 2025 8 اقتباسات

Minerals and Trace Elements: Key Protectors of Skin Health and Defenders against Skin Disorders. Review

Current medicinal chemistry 2025 5 اقتباسات

The role of trace elements for the function and health of the skin. Review

Journal of trace … 2025 4 اقتباسات

Investigation of ischaemia-modified albumin and antioxidant vitamins and minerals levels in alopecia areata patients and evaluation of their relationship with … Other

Cutaneous and ocular … 2025 1 اقتباسات

Medical Marijuana and Treatment Personalization: The Role of Genetics and Epigenetics in Response to THC and CBD. Review

Genes 2025 1 اقتباسات

Trace Elements and Risk of Immune-Mediated Skin Disease: A Systematic Review and Meta-analysis. Meta-Analysis

Nutrition reviews 2025

A comprehensive investigation of biochemical status in patients with telogen effluvium: Analysis of Hb, ferritin, vitamin B12, vitamin D, thyroid … Other

Journal of cosmetic … 2024 7 اقتباسات

Micronutrients and Androgenetic Alopecia: A Systematic Review. Systematic Review

Molecular nutrition & … 2024 7 اقتباسات

Selenium in the supplement as the probable cause of hair loss and nail dystrophy. Other

Journal of cosmetic … 2024 4 اقتباسات

Cannabis-based medicines and medical cannabis for adults with cancer pain. Meta-Analysis

The Cochrane database … 2023 47 اقتباسات

Cautious Hope for Cannabidiol (CBD) in Rheumatology Care. Review

Arthritis care & … 2023 36 اقتباسات

Cannabidiol and brain function: current knowledge and future perspectives. Review

Frontiers in pharmacology 2023 29 اقتباسات

Medical and procedural treatment of androgenetic alopecia - Where are we? Review

Journal of the … 2023 20 اقتباسات

Bartter Syndrome: A Systematic Review of Case Reports and Case Series. Systematic Review

Medicina (Kaunas, Lithuania) 2023 17 اقتباسات

Hemp-Derived CBD Used in Food and Food Supplements. Review

Molecules (Basel, Switzerland) 2023 14 اقتباسات

Efficacy and tolerability of an oral supplement containing amino acids, iron, selenium, and marine hydrolyzed collagen in subjects with hair … RCT

Skin research and … 2023 11 اقتباسات

CANNabinoid Drug Interaction Review (CANN-DIR™). Review

Medical cannabis and … 2023 9 اقتباسات

Safety and risks of CBD oils purchased online: unveiling uncertain quality and vague health claims. Other

Frontiers in pharmacology 2023 8 اقتباسات

Oral supplementation in female telogen effluvium: a clinical and instrumental objective evidence of efficacy and tolerability of new oral cosmetic … Other

Italian journal of … 2023 3 اقتباسات

Effects of a Supplement Containing Cannabidiol (CBD) on Sedation and Ataxia Scores and Health. RCT

Journal of equine … 2022 6 اقتباسات

Acceptability of cannabidiol in patients with psychosis. Other

Therapeutic advances in … 2022 4 اقتباسات

A Review of Hemp as Food and Nutritional Supplement. Review

Cannabis and cannabinoid … 2021 171 اقتباسات

The Pharmacological Case for Cannabigerol. Review

The Journal of … 2021 162 اقتباسات

The Impact of Cannabidiol on Psychiatric and Medical Conditions. Review

Journal of clinical … 2020 42 اقتباسات

Alopecia Areata and Toxic Metals. Other

Skin appendage disorders 2020 10 اقتباسات

The Trouble with CBD Oil. Other

Medical cannabis and … 2018 158 اقتباسات

Nutritional Considerations for the Vegetarian and Vegan Dancer. Review

Journal of dance … 2018 15 اقتباسات

The Role of Micronutrients in Alopecia Areata: A Review. Review

American journal of … 2017 104 اقتباسات

Changes of serum trace elements level in patients with alopecia areata: A meta-analysis. Meta-Analysis

The Journal of … 2017 31 اقتباسات

Trichotillomania: Bizzare Patern of Hair Loss at 11-Year-old Girl. Case Report

Acta dermatovenerologica Croatica … 2016 6 اقتباسات

Vitamin B12 and omega-3 fatty acids together regulate lipid metabolism in Wistar rats. Other

Prostaglandins, leukotrienes, and … 2015 40 اقتباسات

[Vitamins and nutritional supplements in older persons: How to diagnose and when to substitute?]. Review

Der Internist 2015 3 اقتباسات

Micronutrient deficiencies in inflammatory bowel disease: from A to zinc. Review

Inflammatory bowel diseases 2012 224 اقتباسات

[Nutrition and fertility]. Other

Medycyna wieku rozwojowego 2011

A high prevalence of biochemical evidence of vitamin B12 or folate deficiency does not translate into a comparable prevalence of … Review

Food and nutrition … 2008 83 اقتباسات

Vitamin B12, folic acid, and the prevention of dementia. Other

The New England … 2006 47 اقتباسات

Oxidative stress in aldosteronism. Review

Cardiovascular research 2006 42 اقتباسات

Element concentrations in serum, erythrocytes, hair and urine of alopecia patients. Other

Acta dermato-venereologica 1986 53 اقتباسات

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

الجرعات الشائعة

general:: 55 mcg/day

الحد الأعلى: 400 mcg/day

الجرعات المدروسة في الأبحاث

الجرعة	المدة	التأثير	ن
None	--	Positive	2582
None	--	Mixed	7014
None	--	Neutral	30
None	--	Mixed	--
None	--	Mixed	--
None	--	Positive	--
NaSe 5.6ppm, Met 4.7ppm, DPDS 14.2ppm, NanoSe 2.7ppm	4 weeks	Positive	40
not applicable	--	Mixed	180

أفضل وقت للتناول: With meals for better absorption

Safety & Side Effects

الآثار الجانبية المُبلّغ عنها

⚠ Hair loss at excessive doses (selenosis)
⚠ Brittle nails
⚠ Garlic-like breath odor at high doses
⚠ Nausea and diarrhea

التفاعلات المعروفة

● Statins (selenium may reduce statin effectiveness)
● Chemotherapy drugs (antioxidant effects may theoretically interfere)
● Niacin (may decrease HDL-raising effect when combined)

الحد الأقصى المسموح به: 400 mcg/day

استشر مقدم الرعاية الصحية دائماً قبل البدء بأي مكمل غذائي.

Frequently Asked Questions

Does السيلينيوم help with تساقط الشعر المرتبط بالغدة الدرقية?

Based on 38 studies with 10,748 participants, there is strong evidence from multiple clinical trials that السيلينيوم may support تساقط الشعر المرتبط بالغدة الدرقية management. Our evidence grade is A (Strong Evidence).

How much السيلينيوم should I take for تساقط الشعر المرتبط بالغدة الدرقية?

Studies have used various dosages. A commonly studied range is 55 mcg/day. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of السيلينيوم?

Reported side effects may include Hair loss at excessive doses (selenosis), Brittle nails, Garlic-like breath odor at high doses, Nausea and diarrhea. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for السيلينيوم and تساقط الشعر المرتبط بالغدة الدرقية?

We rate the evidence as Grade A (Strong Evidence). This rating is based on 38 peer-reviewed studies with 10,748 total participants. The overall direction of effect is mixed.

Related Evidence

السيلينيوم لحالات أخرى

تساقط الشعر بسبب نقص التغذية A

الخلاصة السريعة

بناءً على 35 دراسة (6 meta-analyses, 5 RCTs) بمشاركة 10,466 مشاركًا إجمالاً. النتائج متباينة بين الدراسات.

Evidence Strength92%

High confidence

تفصيل الدراسات

RCT (2)Meta (3)Other (33)

قارن البدائل

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اعرف المزيد

إخلاء مسؤولية FDA: لم تُقيَّم هذه البيانات من قبل إدارة الغذاء والدواء (FDA). لا تهدف المنتجات والمعلومات الواردة في هذا الموقع إلى تشخيص أو علاج أو شفاء أو الوقاية من أي مرض. تستند تقييمات الأدلة المعروضة إلى تحليلنا للأبحاث المحكّمة المنشورة ولا تُشكّل نصيحة طبية. استشر مقدم الرعاية الصحية دائماً قبل البدء بأي نظام مكملات.