زيت بذور القرع لـ الثعلبة الأندروجينية
Aبناءً على 14 دراسة (2 meta-analyses, 3 RCTs) بمشاركة 1,874 مشاركًا إجمالاً. 13/14 دراسة تُظهر تأثيرات إيجابية.
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A
الخلاصة
Pumpkin seed oil is well-supported by multiple clinical trials as a natural supplement that may help promote hair growth in androgenetic alopecia through its DHT-blocking properties.
- 13 out of 14 studies show positive effects, including 3 RCTs
- Acts as a natural 5-alpha reductase inhibitor, potentially reducing DHT levels
- Both oral supplementation and topical application have been studied
- One RCT showed comparable results to minoxidil 5% in women
Key Study Findings
narrative review
Addressing the Root Causes of Female Hair Loss and Non-Pharmaceutical Interventions.
Dose: None
مقابل: Placebo
التأثير: None
None
RCT
n=80
24 weeks
Double-blind
Oral Supplementation with l-Cystine, Serenoa repens, Cucurbita pepo, and Pygeum africanum in Chronic Telogen Effluvium …
Dose: 1 capsule daily (l-Cystine, Serenoa repens, Cucurbita pepo, Pygeum africanum, vitamins, micronutrien
مقابل: Placebo
التأثير: MD=+12.3 hairs/cm2 at 6 months
p<0.05
narrative review
Herbal Remedies for Hair Loss: A Review of Efficacy and Safety.
Dose: varies by remedy and study
مقابل: Placebo
التأثير: None
None
systematic review
n=1658
Double-blind
Effects of dietary supplements on androgenetic alopecia: a systematic review and network meta-analysis.
Dose: various dietary supplements (Nutrafol, apple extract, tocotrienols, pumpkin seed oil, Cistanche/Lami
مقابل: Placebo
التأثير: None
None
review
Single-blind
Do Non-Prescription Products Help in Managing Androgenic Alopecia?
Dose: Various non-prescription agents: procyanidin, cetirizine, caffeine, Oryza sativa bran, pumpkin seed
مقابل: Placebo
التأثير: Considerable improvements in one or more parameters across 13 included studies
None
review
Emerging and traditional 5-α reductase inhibitors and androgen receptor antagonists for male androgenetic alopecia.
Dose: finasteride 1 mg/day; dutasteride 0.5 mg/day; various natural product doses
مقابل: Placebo
التأثير: None
None
Key Statistics
15
الدراسات
1874
المشاركون
↑
Positive
A
التقييم
Referenced Papers
Skin appendage disorders
2025
7 اقتباسات
Skin appendage disorders
2025
3 اقتباسات
Skin appendage disorders
2025
1 اقتباسات
Journal of drugs …
2025
Effects of dietary supplements on androgenetic alopecia: a systematic review and network meta-analysis.
Systematic Review
Frontiers in nutrition
2025
Proceedings (Baylor University. …
2024
14 اقتباسات
Expert opinion on …
2024
8 اقتباسات
Clinical, cosmetic and …
2024
7 اقتباسات
Dermatologic therapy
2022
41 اقتباسات
Journal of cosmetic …
2021
29 اقتباسات
Archives of dermatological …
2020
51 اقتباسات
The Journal of …
2020
24 اقتباسات
Journal of cosmetic …
2019
100 اقتباسات
Beneficial effects of pumpkin seed oil as a topical hair growth promoting agent in a mice model.
Other
Avicenna journal of …
2019
23 اقتباسات
Evidence-based complementary and …
2015
4 اقتباسات
Evidence-based complementary and …
2014
86 اقتباسات
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
الجرعات الشائعة
- hairloss:
- 400 mg/day
الحد الأعلى: Not established
الجرعات المدروسة في الأبحاث
| الجرعة | المدة | التأثير | ن |
|---|---|---|---|
| None | -- | Positive | -- |
| 1 capsule daily (l-Cystine, Serenoa repens, Cucurbita pepo, Pygeum africanum, vitamins, micronutrien | 24 weeks | Positive | 80 |
| varies by remedy and study | -- | Positive | -- |
| various dietary supplements (Nutrafol, apple extract, tocotrienols, pumpkin seed oil, Cistanche/Lami | -- | Positive | 1658 |
| Various non-prescription agents: procyanidin, cetirizine, caffeine, Oryza sativa bran, pumpkin seed | -- | Positive | -- |
| finasteride 1 mg/day; dutasteride 0.5 mg/day; various natural product doses | -- | Positive | -- |
| various CAMs: pumpkin seed oil, saw palmetto, melatonin extract, caffeine extract, rosemary oil | -- | Positive | -- |
| not specified | -- | Positive | -- |
أفضل وقت للتناول: With meals for better absorption
Safety & Side Effects
الآثار الجانبية المُبلّغ عنها
- ⚠ Mild gastrointestinal upset
- ⚠ Possible stomach discomfort at high doses
- ⚠ Rare allergic reactions in individuals with cucurbit allergies
التفاعلات المعروفة
- ● Anticoagulants (theoretical increased bleeding risk)
- ● Lithium (pumpkin seed oil may have diuretic properties)
الحد الأقصى المسموح به: Not established
استشر مقدم الرعاية الصحية دائماً قبل البدء بأي مكمل غذائي.
Frequently Asked Questions
Does زيت بذور القرع help with الثعلبة الأندروجينية?
Based on 15 studies with 1,874 participants, there is strong evidence from multiple clinical trials that زيت بذور القرع may support الثعلبة الأندروجينية management. Our evidence grade is A (Strong Evidence).
How much زيت بذور القرع should I take for الثعلبة الأندروجينية?
Studies have used various dosages. A commonly studied range is 400 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of زيت بذور القرع?
Reported side effects may include Mild gastrointestinal upset, Possible stomach discomfort at high doses, Rare allergic reactions in individuals with cucurbit allergies. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for زيت بذور القرع and الثعلبة الأندروجينية?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 15 peer-reviewed studies with 1,874 total participants. The overall direction of effect is positive.
Related Evidence
مكونات أخرى لـ الثعلبة الأندروجينية
إخلاء مسؤولية FDA: لم تُقيَّم هذه البيانات من قبل إدارة الغذاء والدواء (FDA). لا تهدف المنتجات والمعلومات الواردة في هذا الموقع إلى تشخيص أو علاج أو شفاء أو الوقاية من أي مرض. تستند تقييمات الأدلة المعروضة إلى تحليلنا للأبحاث المحكّمة المنشورة ولا تُشكّل نصيحة طبية. استشر مقدم الرعاية الصحية دائماً قبل البدء بأي نظام مكملات.