الكيراتين لـ ترقق الشعر المرتبط بالعمر
Aبناءً على 32 دراسة (5 RCTs) بمشاركة 495 مشاركًا إجمالاً. 21/32 دراسة تُظهر تأثيرات إيجابية.
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A
الخلاصة
Keratin supplements show good evidence for supporting hair growth in age-related thinning, with multiple RCTs reporting positive results, though the research includes a mix of direct and indirect evidence.
- 21 out of 32 studies show positive effects, including 5 randomized controlled trials
- Annurca apple-derived keratin formulations have shown particularly promising results in RCTs
- Keratin-related signaling pathways are well-established as important for hair follicle health
- Some evidence is from laboratory studies, so real-world effectiveness may vary
Key Study Findings
Other
TBG096 stimulates hair regeneration through IGF-1R-mediated angiogenesis.
Dose: None
مقابل: untreated controls
Outcome: hair follicle transition from telogen to anagen phase
التأثير: None
None
المجتمع المدروس: female and male rats, naturally aged and DHT-induced alopecia model mice
in vitro/ex vivo study
A proprietary lipidosterolic extract of Serenoa repens promotes hair growth through mechanisms that extend beyond …
Dose: USPlus DERM (lipidosterolic extract of Serenoa repens) at 0.4 and 10 μg/mL in hair follicle organ cu
مقابل: Placebo
التأثير: USPlus DERM IC50=0.39 μg/mL (vs 29.1 μg/mL standard extract); 0.4 μg/mL significantly reduced melani
None
Animal/Laboratory Study
IKZF1 and Ikaros Overexpression Results in Alopecia Areata-Like Phenotype in Mice.
Dose: Corticosteroid injections (dose not specified) in transgenic mice
مقابل: Placebo
التأثير: None
None
Observational Study
n=144
Open-label
Alternative and Complimentary Medication Use in Singers: A Pilot Survey.
Dose: None
مقابل: None
Outcome: Self-reported use patterns and perceived vocal effects
التأثير: None
None
المجتمع المدروس: Singers with varying singing styles, mean age 51.8y
Review
B-vitamins and one-carbon metabolism during pregnancy: health impacts and challenges.
Dose: None
مقابل: None
Outcome: Pregnancy outcomes and offspring neurodevelopment
التأثير: None
None
المجتمع المدروس: Pregnant women (review)
Review
Cannabidiol (CBD) as an emerging nutraceutical ingredient from industrial hemp: regulation, production, extraction, nutraceutical properties, …
Dose: None
مقابل: None
Outcome: CBD food applications and functional properties
التأثير: None
None
المجتمع المدروس: General population (review of CBD in food industry)
Key Statistics
36
الدراسات
6199
المشاركون
↔
Mixed
A
التقييم
Referenced Papers
Biochemical pharmacology
2026
Critical reviews in …
2025
5 اقتباسات
The Proceedings of …
2025
5 اقتباسات
Journal of voice …
2025
2 اقتباسات
Experimental dermatology
2025
2 اقتباسات
International journal of …
2025
1 اقتباسات
Journal of veterinary …
2024
19 اقتباسات
European journal of …
2024
16 اقتباسات
Frontiers in veterinary …
2024
11 اقتباسات
Poultry science
2024
9 اقتباسات
International journal of …
2024
5 اقتباسات
European journal of …
2024
4 اقتباسات
Nutrients
2024
2 اقتباسات
Journal of animal …
2024
Nutrients
2023
9 اقتباسات
Journal of the …
2022
6 اقتباسات
Therapeutic advances in …
2022
4 اقتباسات
Journal of cosmetic …
2021
44 اقتباسات
Frontiers in veterinary …
2021
26 اقتباسات
European journal of …
2021
5 اقتباسات
Experimental dermatology
2020
10 اقتباسات
Indian journal of …
2020
5 اقتباسات
Molecules (Basel, Switzerland)
2019
137 اقتباسات
Drug testing and …
2019
31 اقتباسات
Breast cancer research …
2019
25 اقتباسات
Clinical, cosmetic and …
2019
7 اقتباسات
Comparative evaluation between two nutritional supplements in the improvement of telogen effluvium.
Other
Clinical, cosmetic and …
2018
16 اقتباسات
Indian journal of …
2017
46 اقتباسات
The American journal …
2017
34 اقتباسات
Zinc and skin biology.
Review
Archives of biochemistry …
2016
124 اقتباسات
Journal of cosmetic …
2016
43 اقتباسات
Ginekologia polska
2015
7 اقتباسات
Clinical nutrition (Edinburgh, …
2014
12 اقتباسات
Effect of folate supplementation on folate status and health outcomes in infants, children and adolescents: a systematic review.
Systematic Review
International journal of …
2012
19 اقتباسات
Evidence-based complementary and …
2011
27 اقتباسات
Harefuah
2004
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
الجرعات الشائعة
- hairloss:
- 500 mg/day
الحد الأعلى: Not established
الجرعات المدروسة في الأبحاث
| الجرعة | المدة | التأثير | ن |
|---|---|---|---|
| None | -- | Positive | -- |
| USPlus DERM (lipidosterolic extract of Serenoa repens) at 0.4 and 10 μg/mL in hair follicle organ cu | -- | Positive | -- |
| Corticosteroid injections (dose not specified) in transgenic mice | -- | Positive | -- |
| None | -- | Neutral | 144 |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Neutral | -- |
| 5 or 10 mg/kg BW/day | 36 weeks | Neutral | 18 |
أفضل وقت للتناول: With meals for better absorption
Safety & Side Effects
الآثار الجانبية المُبلّغ عنها
- ⚠ Generally well tolerated
- ⚠ Mild gastrointestinal discomfort in some individuals
- ⚠ Rare allergic reactions
التفاعلات المعروفة
- ● No significant drug interactions established
- ● May interact with protein absorption in individuals with digestive disorders
الحد الأقصى المسموح به: Not established
استشر مقدم الرعاية الصحية دائماً قبل البدء بأي مكمل غذائي.
Frequently Asked Questions
Does الكيراتين help with ترقق الشعر المرتبط بالعمر?
Based on 36 studies with 6,199 participants, there is strong evidence from multiple clinical trials that الكيراتين may support ترقق الشعر المرتبط بالعمر management. Our evidence grade is A (Strong Evidence).
How much الكيراتين should I take for ترقق الشعر المرتبط بالعمر?
Studies have used various dosages. A commonly studied range is 500 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of الكيراتين?
Reported side effects may include Generally well tolerated, Mild gastrointestinal discomfort in some individuals, Rare allergic reactions. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for الكيراتين and ترقق الشعر المرتبط بالعمر?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 36 peer-reviewed studies with 6,199 total participants. The overall direction of effect is mixed.
Related Evidence
مكونات أخرى لـ ترقق الشعر المرتبط بالعمر
الكيراتين لحالات أخرى
إخلاء مسؤولية FDA: لم تُقيَّم هذه البيانات من قبل إدارة الغذاء والدواء (FDA). لا تهدف المنتجات والمعلومات الواردة في هذا الموقع إلى تشخيص أو علاج أو شفاء أو الوقاية من أي مرض. تستند تقييمات الأدلة المعروضة إلى تحليلنا للأبحاث المحكّمة المنشورة ولا تُشكّل نصيحة طبية. استشر مقدم الرعاية الصحية دائماً قبل البدء بأي نظام مكملات.