케라틴 관련 노화성 모발 가늘어짐
A 근거 여러 대규모 임상 시험이 일관되게 유의미한 효과를 보여줍니다.총 495명의 참여자를 대상으로 한 32건의 연구(RCT 5건)에 근거합니다. 32건 중 21건의 연구에서 긍정적인 효과가 나타났습니다.
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A
결론
Keratin supplements show good evidence for supporting hair growth in age-related thinning, with multiple RCTs reporting positive results, though the research includes a mix of direct and indirect evidence.
- 21 out of 32 studies show positive effects, including 5 randomized controlled trials
- Annurca apple-derived keratin formulations have shown particularly promising results in RCTs
- Keratin-related signaling pathways are well-established as important for hair follicle health
- Some evidence is from laboratory studies, so real-world effectiveness may vary
Key Study Findings
Other
TBG096 stimulates hair regeneration through IGF-1R-mediated angiogenesis.
Dose: None
vs: untreated controls
Outcome: hair follicle transition from telogen to anagen phase
효과: None
None
대상 집단: female and male rats, naturally aged and DHT-induced alopecia model mice
in vitro/ex vivo study
A proprietary lipidosterolic extract of Serenoa repens promotes hair growth through mechanisms that extend beyond …
Dose: USPlus DERM (lipidosterolic extract of Serenoa repens) at 0.4 and 10 μg/mL in hair follicle organ cu
vs: Placebo
효과: USPlus DERM IC50=0.39 μg/mL (vs 29.1 μg/mL standard extract); 0.4 μg/mL significantly reduced melani
None
Animal/Laboratory Study
IKZF1 and Ikaros Overexpression Results in Alopecia Areata-Like Phenotype in Mice.
Dose: Corticosteroid injections (dose not specified) in transgenic mice
vs: Placebo
효과: None
None
Observational Study
n=144
Open-label
Alternative and Complimentary Medication Use in Singers: A Pilot Survey.
Dose: None
vs: None
Outcome: Self-reported use patterns and perceived vocal effects
효과: None
None
대상 집단: Singers with varying singing styles, mean age 51.8y
Review
B-vitamins and one-carbon metabolism during pregnancy: health impacts and challenges.
Dose: None
vs: None
Outcome: Pregnancy outcomes and offspring neurodevelopment
효과: None
None
대상 집단: Pregnant women (review)
Review
Cannabidiol (CBD) as an emerging nutraceutical ingredient from industrial hemp: regulation, production, extraction, nutraceutical properties, …
Dose: None
vs: None
Outcome: CBD food applications and functional properties
효과: None
None
대상 집단: General population (review of CBD in food industry)
Key Statistics
36
연구
6199
참여자
↔
Mixed
A
등급
Referenced Papers
Biochemical pharmacology
2026
Critical reviews in …
2025
5 인용
The Proceedings of …
2025
5 인용
Journal of voice …
2025
2 인용
Experimental dermatology
2025
2 인용
International journal of …
2025
1 인용
Journal of veterinary …
2024
19 인용
European journal of …
2024
16 인용
Frontiers in veterinary …
2024
11 인용
Poultry science
2024
9 인용
International journal of …
2024
5 인용
European journal of …
2024
4 인용
Nutrients
2024
2 인용
Journal of animal …
2024
Nutrients
2023
9 인용
Journal of the …
2022
6 인용
Therapeutic advances in …
2022
4 인용
Journal of cosmetic …
2021
44 인용
Frontiers in veterinary …
2021
26 인용
European journal of …
2021
5 인용
Experimental dermatology
2020
10 인용
Indian journal of …
2020
5 인용
Molecules (Basel, Switzerland)
2019
137 인용
Drug testing and …
2019
31 인용
Breast cancer research …
2019
25 인용
Clinical, cosmetic and …
2019
7 인용
Comparative evaluation between two nutritional supplements in the improvement of telogen effluvium.
Other
Clinical, cosmetic and …
2018
16 인용
Indian journal of …
2017
46 인용
The American journal …
2017
34 인용
Zinc and skin biology.
Review
Archives of biochemistry …
2016
124 인용
Journal of cosmetic …
2016
43 인용
Ginekologia polska
2015
7 인용
Clinical nutrition (Edinburgh, …
2014
12 인용
Effect of folate supplementation on folate status and health outcomes in infants, children and adolescents: a systematic review.
Systematic Review
International journal of …
2012
19 인용
Evidence-based complementary and …
2011
27 인용
Harefuah
2004
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
일반적으로 사용되는 용량
- hairloss:
- 500 mg/day
상한량: Not established
연구에서 사용된 용량
| 용량 | 기간 | 효과 | N |
|---|---|---|---|
| None | -- | Positive | -- |
| USPlus DERM (lipidosterolic extract of Serenoa repens) at 0.4 and 10 μg/mL in hair follicle organ cu | -- | Positive | -- |
| Corticosteroid injections (dose not specified) in transgenic mice | -- | Positive | -- |
| None | -- | Neutral | 144 |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Neutral | -- |
| 5 or 10 mg/kg BW/day | 36 weeks | Neutral | 18 |
권장 복용 시간: With meals for better absorption
Safety & Side Effects
보고된 부작용
- ⚠ Generally well tolerated
- ⚠ Mild gastrointestinal discomfort in some individuals
- ⚠ Rare allergic reactions
알려진 상호작용
- ● No significant drug interactions established
- ● May interact with protein absorption in individuals with digestive disorders
일일 최대 섭취 허용량: Not established
건강기능식품을 복용하기 전에 반드시 의료 전문가와 상담하십시오.
Frequently Asked Questions
Does 케라틴 help with 노화성 모발 가늘어짐?
Based on 36 studies with 6,199 participants, there is strong evidence from multiple clinical trials that 케라틴 may support 노화성 모발 가늘어짐 management. Our evidence grade is A (Strong Evidence).
How much 케라틴 should I take for 노화성 모발 가늘어짐?
Studies have used various dosages. A commonly studied range is 500 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of 케라틴?
Reported side effects may include Generally well tolerated, Mild gastrointestinal discomfort in some individuals, Rare allergic reactions. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for 케라틴 and 노화성 모발 가늘어짐?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 36 peer-reviewed studies with 6,199 total participants. The overall direction of effect is mixed.
Related Evidence
References
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