Keratin için Yaşa Bağlı Saç İncelmesi
A Kanıt Birden fazla büyük klinik çalışma tutarlı biçimde önemli faydalar ortaya koymaktadır.32 çalışmaya (5 RCTs), toplam 495 katılımcıyla dayanmaktadır. 21/32 çalışma olumlu etkiler göstermektedir.
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A
Sonuç
Keratin supplements show good evidence for supporting hair growth in age-related thinning, with multiple RCTs reporting positive results, though the research includes a mix of direct and indirect evidence.
- 21 out of 32 studies show positive effects, including 5 randomized controlled trials
- Annurca apple-derived keratin formulations have shown particularly promising results in RCTs
- Keratin-related signaling pathways are well-established as important for hair follicle health
- Some evidence is from laboratory studies, so real-world effectiveness may vary
Key Study Findings
Other
TBG096 stimulates hair regeneration through IGF-1R-mediated angiogenesis.
Dose: None
vs: untreated controls
Outcome: hair follicle transition from telogen to anagen phase
Etki: None
None
Popülasyon: female and male rats, naturally aged and DHT-induced alopecia model mice
in vitro/ex vivo study
A proprietary lipidosterolic extract of Serenoa repens promotes hair growth through mechanisms that extend beyond …
Dose: USPlus DERM (lipidosterolic extract of Serenoa repens) at 0.4 and 10 μg/mL in hair follicle organ cu
vs: Placebo
Etki: USPlus DERM IC50=0.39 μg/mL (vs 29.1 μg/mL standard extract); 0.4 μg/mL significantly reduced melani
None
Animal/Laboratory Study
IKZF1 and Ikaros Overexpression Results in Alopecia Areata-Like Phenotype in Mice.
Dose: Corticosteroid injections (dose not specified) in transgenic mice
vs: Placebo
Etki: None
None
Observational Study
n=144
Open-label
Alternative and Complimentary Medication Use in Singers: A Pilot Survey.
Dose: None
vs: None
Outcome: Self-reported use patterns and perceived vocal effects
Etki: None
None
Popülasyon: Singers with varying singing styles, mean age 51.8y
Review
B-vitamins and one-carbon metabolism during pregnancy: health impacts and challenges.
Dose: None
vs: None
Outcome: Pregnancy outcomes and offspring neurodevelopment
Etki: None
None
Popülasyon: Pregnant women (review)
Review
Cannabidiol (CBD) as an emerging nutraceutical ingredient from industrial hemp: regulation, production, extraction, nutraceutical properties, …
Dose: None
vs: None
Outcome: CBD food applications and functional properties
Etki: None
None
Popülasyon: General population (review of CBD in food industry)
Key Statistics
36
Çalışmalar
6199
Katılımcılar
↔
Mixed
A
Derece
Referenced Papers
Biochemical pharmacology
2026
Critical reviews in …
2025
5 atıf
The Proceedings of …
2025
5 atıf
Journal of voice …
2025
2 atıf
Experimental dermatology
2025
2 atıf
International journal of …
2025
1 atıf
Journal of veterinary …
2024
19 atıf
European journal of …
2024
16 atıf
Frontiers in veterinary …
2024
11 atıf
Poultry science
2024
9 atıf
International journal of …
2024
5 atıf
European journal of …
2024
4 atıf
Nutrients
2024
2 atıf
Journal of animal …
2024
Nutrients
2023
9 atıf
Journal of the …
2022
6 atıf
Therapeutic advances in …
2022
4 atıf
Journal of cosmetic …
2021
44 atıf
Frontiers in veterinary …
2021
26 atıf
European journal of …
2021
5 atıf
Experimental dermatology
2020
10 atıf
Indian journal of …
2020
5 atıf
Molecules (Basel, Switzerland)
2019
137 atıf
Drug testing and …
2019
31 atıf
Breast cancer research …
2019
25 atıf
Clinical, cosmetic and …
2019
7 atıf
Comparative evaluation between two nutritional supplements in the improvement of telogen effluvium.
Other
Clinical, cosmetic and …
2018
16 atıf
Indian journal of …
2017
46 atıf
The American journal …
2017
34 atıf
Zinc and skin biology.
Review
Archives of biochemistry …
2016
124 atıf
Journal of cosmetic …
2016
43 atıf
Ginekologia polska
2015
7 atıf
Clinical nutrition (Edinburgh, …
2014
12 atıf
Effect of folate supplementation on folate status and health outcomes in infants, children and adolescents: a systematic review.
Systematic Review
International journal of …
2012
19 atıf
Evidence-based complementary and …
2011
27 atıf
Harefuah
2004
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Yaygın Kullanılan Dozajlar
- hairloss:
- 500 mg/day
Üst sınır: Not established
Araştırmalarda İncelenen Dozajlar
| Dozaj | Süre | Etki | N |
|---|---|---|---|
| None | -- | Positive | -- |
| USPlus DERM (lipidosterolic extract of Serenoa repens) at 0.4 and 10 μg/mL in hair follicle organ cu | -- | Positive | -- |
| Corticosteroid injections (dose not specified) in transgenic mice | -- | Positive | -- |
| None | -- | Neutral | 144 |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Neutral | -- |
| 5 or 10 mg/kg BW/day | 36 weeks | Neutral | 18 |
En iyi alım zamanı: With meals for better absorption
Safety & Side Effects
Bildirilen Yan Etkiler
- ⚠ Generally well tolerated
- ⚠ Mild gastrointestinal discomfort in some individuals
- ⚠ Rare allergic reactions
Bilinen Etkileşimler
- ● No significant drug interactions established
- ● May interact with protein absorption in individuals with digestive disorders
Tolere edilebilir üst alım: Not established
Herhangi bir takviye kullanmaya başlamadan önce mutlaka sağlık uzmanınıza danışın.Herhangi bir takviye başlatmadan önce her zaman sağlık uzmanınıza danışın.
Frequently Asked Questions
Does Keratin help with Yaşa Bağlı Saç İncelmesi?
Based on 36 studies with 6,199 participants, there is strong evidence from multiple clinical trials that Keratin may support Yaşa Bağlı Saç İncelmesi management. Our evidence grade is A (Strong Evidence).
How much Keratin should I take for Yaşa Bağlı Saç İncelmesi?
Studies have used various dosages. A commonly studied range is 500 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Keratin?
Reported side effects may include Generally well tolerated, Mild gastrointestinal discomfort in some individuals, Rare allergic reactions. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Keratin and Yaşa Bağlı Saç İncelmesi?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 36 peer-reviewed studies with 6,199 total participants. The overall direction of effect is mixed.
Related Evidence
Şu durum için diğer içerikler: Yaşa Bağlı Saç İncelmesi
Keratin diğer sağlık durumları için
References
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