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用于 休止期脱发

B

基于56项研究(2项RCT),共11,067名参与者。各研究结果不一。

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B

结论

Iron may support recovery from telogen effluvium, particularly when low ferritin levels are confirmed, but the evidence is mixed and routine supplementation without testing is not well-supported.

  • 56 studies provide substantial evidence, though results are mixed across the research
  • Lower ferritin levels are commonly found in patients with telogen effluvium
  • One study found iron supplementation improved satisfaction even in patients without overtly low ferritin
  • Blood testing for ferritin and iron levels is recommended before starting supplementation

Key Study Findings

Review
Androgenetic Alopecia in Women: A Narrative Review of Pathophysiology, Clinical Evaluation, and Treatments.
Dose: None vs: None Outcome: None 效果: None None

研究人群: women with androgenetic alopecia (female pattern hair loss)

scoping_review n=16
A Scoping Review of Exosome Delivery Applications in Hair Loss.
Dose: variable; exosomes predominantly from mesenchymal stem cells (MSCs) vs: Placebo 效果: None None
Retrospective cohort n=2851
Retrospective Review of 2851 Female Patients With Telogen Effluvium: A Single-Center Experience.
Dose: None vs: Placebo 效果: Ferritin low in 46.5% of patients; iron deficiency in 29.5% p<0.05
review
The role of microtrauma in hair regrowth and regeneration in non-scarring alopecia.
Dose: Various microtrauma procedures: microneedling, fractional/non-fractional lasers, contact immunothera vs: Placebo 效果: Positive outcomes reported for hair density and thickness with microneedling, lasers, LLLT, and PRP None

Key Statistics

62

研究数量

11072

受试者

Mixed

B

等级

Referenced Papers

Journal of drugs … 2021 3 次引用
Acta dermatovenerologica Croatica … 2016 6 次引用
Journal of clinical … 2015 190 次引用
The Medical clinics … 2015 66 次引用
Clinical obstetrics and … 2015 9 次引用
Turkish journal of … 2014 5 次引用
Annals of gastroenterology 2014 5 次引用
Skin pharmacology and … 2013 127 次引用
Seminars in cutaneous … 2006 23 次引用
American journal of … 2005 140 次引用
Journal of the … 2005 64 次引用
Revue medicale de … 2004
The Journal of … 2003 222 次引用
International journal of … 2002 95 次引用
Dermatologic clinics 1993 38 次引用

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

常用剂量

general:
18 mg/day (women)
deficiency:
65-200 mg elemental iron/day

上限: 45 mg/day

研究中使用的剂量

剂量 持续时间 效果 N
None -- Neutral --
variable; exosomes predominantly from mesenchymal stem cells (MSCs) -- Positive 16
None -- Mixed --
None -- Neutral 2851
Various microtrauma procedures: microneedling, fractional/non-fractional lasers, contact immunothera -- Positive --
None -- Positive --
not applicable (observational; serum ferritin measured) -- Negative 100
None -- Mixed --

最佳服用时间: On an empty stomach with vitamin C for best absorption; take 2 hours apart from calcium

Safety & Side Effects

已报告的副作用

  • Constipation (most common)
  • Nausea and stomach cramps
  • Dark or black stools
  • Iron overload with excessive supplementation (hemochromatosis risk)

已知相互作用

  • Calcium supplements and dairy (reduce iron absorption by 50-60%)
  • Proton pump inhibitors (omeprazole) and H2 blockers reduce absorption
  • Tetracycline and quinolone antibiotics (mutual absorption reduction)
  • Levothyroxine (iron reduces thyroid hormone absorption)

可耐受最高摄入量: 45 mg/day

在开始服用任何补充剂之前,请务必咨询您的医疗保健提供者。

Frequently Asked Questions

Does 铁 help with 休止期脱发?
Based on 62 studies with 11,072 participants, there is moderate evidence from clinical studies that 铁 may support 休止期脱发 management. Our evidence grade is B (Good Evidence).
How much 铁 should I take for 休止期脱发?
Studies have used various dosages. A commonly studied range is 18 mg/day (women). Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of 铁?
Reported side effects may include Constipation (most common), Nausea and stomach cramps, Dark or black stools, Iron overload with excessive supplementation (hemochromatosis risk). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for 铁 and 休止期脱发?
We rate the evidence as Grade B (Good Evidence). This rating is based on 62 peer-reviewed studies with 11,072 total participants. The overall direction of effect is mixed.

Related Evidence

FDA 免责声明: 这些声明未经美国食品药品监督管理局(FDA)评估。本网站上的产品和信息无意用于诊断、治疗、治愈或预防任何疾病。所展示的证据等级基于我们对已发表的同行评审研究的分析,不构成医疗建议。在开始任何补充剂方案之前,请务必咨询您的医疗保健提供者。