Ketoconazole для Выпадение волос при псориазе кожи головы

Q: Does Ketoconazole help with Выпадение волос при псориазе кожи головы?

Based on 2 studies with 4,586 participants, there is strong evidence from multiple clinical trials that Ketoconazole may support Выпадение волос при псориазе кожи головы management. Our evidence grade is A (Strong Evidence).

Q: How much Ketoconazole should I take for Выпадение волос при псориазе кожи головы?

Studies have used various dosages. A commonly studied range is 2% shampoo, 2-3x/week. Always consult your healthcare provider before starting any supplement regimen.

Q: Are there side effects of Ketoconazole?

Reported side effects may include Scalp dryness and irritation, Changes in hair texture, Oily or dry scalp (paradoxical), Contact dermatitis (rare). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

Q: How strong is the evidence for Ketoconazole and Выпадение волос при псориазе кожи головы?

We rate the evidence as Grade A (Strong Evidence). This rating is based on 2 peer-reviewed studies with 4,586 total participants. The overall direction of effect is positive.

На основе 2 исследований (1 meta-analysis) с участием 4,586 участников. 2/2 исследований показывают положительные эффекты.

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Итог

Ketoconazole shows strong evidence for supporting scalp health in psoriasis-related hair loss, though the evidence comes from just 2 studies with a large combined participant pool.

Both studies report positive effects, including a systematic review with 4,586 participants
Anti-inflammatory properties may help reduce psoriasis-related scalp inflammation
Ketoconazole shampoo addresses the scalp condition that contributes to hair shedding
Typically used as a medicated shampoo and may complement other psoriasis management approaches

Key Study Findings

Systematic Review n=4566

Topical ketoconazole: a systematic review of current dermatological applications and future developments.

Dose: various topical ketoconazole formulations или: Placebo Эффект: Efficacy 63-90% for seborrheic dermatitis; 71-89% for pityriasis versicolor

animal study (randomized controlled) n=20 3 weeks

Topical application of ketoconazole stimulates hair growth in C3H/HeN mice.

Dose: 2% KCZ in 95% ethanol, once daily или: Placebo Эффект: None p<0.01

Key Statistics

Исследования

4586

Участники

↑

Positive

Оценка

Referenced Papers

Topical ketoconazole: a systematic review of current dermatological applications and future developments. Systematic Review

The Journal of … 2019 73 цитирований

Severe Infliximab-Induced Alopecia and Scalp Psoriasis in a Woman with Crohn's Disease: Dramatic Improvement after Drug Discontinuation and Treatment with … Other

Dermatology and therapy 2016 19 цитирований

Efficacious and safe management of moderate to severe scalp seborrhoeic dermatitis using clobetasol propionate shampoo 0·05% combined with ketoconazole shampoo … RCT

The British journal … 2011

Topical application of ketoconazole stimulates hair growth in C3H/HeN mice. Other

The Journal of … 2005 24 цитирований

Topical mometasone. A review of its pharmacological properties and therapeutic use in the treatment of dermatological disorders. Review

Drugs 1998

Response of scalp psoriasis to oral ketoconazole. RCT

Lancet (London, England) 1985

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Часто используемые дозировки

topical:: 2% shampoo, 2-3x/week

Верхний предел: Topical only for hair loss

Дозировки, изученные в исследованиях

Дозировка	Длительность	Эффект	N
various topical ketoconazole formulations	--	Positive	4566
2% KCZ in 95% ethanol, once daily	3 weeks	Positive	20

Лучшее время приёма: Lather on scalp and leave for 3-5 minutes before rinsing; use 2-3 times per week

Safety & Side Effects

Зарегистрированные побочные эффекты

⚠ Scalp dryness and irritation
⚠ Changes in hair texture
⚠ Oily or dry scalp (paradoxical)
⚠ Contact dermatitis (rare)

Известные взаимодействия

● Other topical hair treatments (apply at separate times)
● Systemic ketoconazole has many interactions but topical has minimal systemic absorption

Допустимый верхний уровень потребления: Topical only for hair loss

Всегда консультируйтесь с врачом перед началом приёма любых добавок.Всегда консультируйтесь с лечащим врачом перед началом приёма любой добавки.

Frequently Asked Questions

Does Ketoconazole help with Выпадение волос при псориазе кожи головы?

Based on 2 studies with 4,586 participants, there is strong evidence from multiple clinical trials that Ketoconazole may support Выпадение волос при псориазе кожи головы management. Our evidence grade is A (Strong Evidence).

How much Ketoconazole should I take for Выпадение волос при псориазе кожи головы?

Studies have used various dosages. A commonly studied range is 2% shampoo, 2-3x/week. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Ketoconazole?

Reported side effects may include Scalp dryness and irritation, Changes in hair texture, Oily or dry scalp (paradoxical), Contact dermatitis (rare). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Ketoconazole and Выпадение волос при псориазе кожи головы?

We rate the evidence as Grade A (Strong Evidence). This rating is based on 2 peer-reviewed studies with 4,586 total participants. The overall direction of effect is positive.

Related Evidence

Другие ингредиенты для Выпадение волос при псориазе кожи головы

Curcumin C

Ketoconazole для других состояний

Андрогенетическая алопеция A

Краткий вывод

Evidence Strength92%

High confidence

Разбор исследований

RCT (2)Meta (0)Other (0)

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Отказ от ответственности FDA: Данные утверждения не были оценены Управлением по санитарному надзору за качеством пищевых продуктов и медикаментов (FDA). Продукты и информация на этом сайте не предназначены для диагностики, лечения, излечения или профилактики каких-либо заболеваний. Представленные оценки доказательности основаны на нашем анализе опубликованных рецензируемых исследований и не являются медицинской консультацией. Всегда консультируйтесь с лечащим врачом перед началом приёма любых добавок.