ケトコナゾール：頭皮乾癬に伴う脱毛

Q: Does ケトコナゾール help with 頭皮乾癬に伴う脱毛?

Based on 2 studies with 4,586 participants, there is strong evidence from multiple clinical trials that ケトコナゾール may support 頭皮乾癬に伴う脱毛 management. Our evidence grade is A (Strong Evidence).

Q: How much ケトコナゾール should I take for 頭皮乾癬に伴う脱毛?

Studies have used various dosages. A commonly studied range is 2% shampoo, 2-3x/week. Always consult your healthcare provider before starting any supplement regimen.

Q: Are there side effects of ケトコナゾール?

Reported side effects may include Scalp dryness and irritation, Changes in hair texture, Oily or dry scalp (paradoxical), Contact dermatitis (rare). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

Q: How strong is the evidence for ケトコナゾール and 頭皮乾癬に伴う脱毛?

We rate the evidence as Grade A (Strong Evidence). This rating is based on 2 peer-reviewed studies with 4,586 total participants. The overall direction of effect is positive.

A エビデンス複数の大規模臨床試験が一貫して有意な効果を示しています。

合計4,586名の参加者を対象とした2件の研究（メタアナリシス1件を含む）に基づく。2件中2件の研究で肯定的な効果が示されている。

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結論

Ketoconazole shows strong evidence for supporting scalp health in psoriasis-related hair loss, though the evidence comes from just 2 studies with a large combined participant pool.

Both studies report positive effects, including a systematic review with 4,586 participants
Anti-inflammatory properties may help reduce psoriasis-related scalp inflammation
Ketoconazole shampoo addresses the scalp condition that contributes to hair shedding
Typically used as a medicated shampoo and may complement other psoriasis management approaches

Key Study Findings

Systematic Review n=4566

Topical ketoconazole: a systematic review of current dermatological applications and future developments.

Dose: various topical ketoconazole formulations vs: Placebo 効果: Efficacy 63-90% for seborrheic dermatitis; 71-89% for pityriasis versicolor

animal study (randomized controlled) n=20 3 weeks

Topical application of ketoconazole stimulates hair growth in C3H/HeN mice.

Dose: 2% KCZ in 95% ethanol, once daily vs: Placebo 効果: None p<0.01

Key Statistics

研究数

4586

参加者数

↑

Positive

グレード

Referenced Papers

Topical ketoconazole: a systematic review of current dermatological applications and future developments. Systematic Review

The Journal of … 2019 73 件の引用

Severe Infliximab-Induced Alopecia and Scalp Psoriasis in a Woman with Crohn's Disease: Dramatic Improvement after Drug Discontinuation and Treatment with … Other

Dermatology and therapy 2016 19 件の引用

Efficacious and safe management of moderate to severe scalp seborrhoeic dermatitis using clobetasol propionate shampoo 0·05% combined with ketoconazole shampoo … RCT

The British journal … 2011

Topical application of ketoconazole stimulates hair growth in C3H/HeN mice. Other

The Journal of … 2005 24 件の引用

Topical mometasone. A review of its pharmacological properties and therapeutic use in the treatment of dermatological disorders. Review

Drugs 1998

Response of scalp psoriasis to oral ketoconazole. RCT

Lancet (London, England) 1985

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

一般的な使用量

topical:: 2% shampoo, 2-3x/week

上限量： Topical only for hair loss

研究で検討された用量

用量	期間	効果	N
various topical ketoconazole formulations	--	Positive	4566
2% KCZ in 95% ethanol, once daily	3 weeks	Positive	20

推奨摂取タイミング： Lather on scalp and leave for 3-5 minutes before rinsing; use 2-3 times per week

Safety & Side Effects

報告されている副作用

⚠ Scalp dryness and irritation
⚠ Changes in hair texture
⚠ Oily or dry scalp (paradoxical)
⚠ Contact dermatitis (rare)

既知の相互作用

● Other topical hair treatments (apply at separate times)
● Systemic ketoconazole has many interactions but topical has minimal systemic absorption

耐容上限摂取量： Topical only for hair loss

サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。

Frequently Asked Questions

Does ケトコナゾール help with 頭皮乾癬に伴う脱毛?

Based on 2 studies with 4,586 participants, there is strong evidence from multiple clinical trials that ケトコナゾール may support 頭皮乾癬に伴う脱毛 management. Our evidence grade is A (Strong Evidence).

How much ケトコナゾール should I take for 頭皮乾癬に伴う脱毛?

Studies have used various dosages. A commonly studied range is 2% shampoo, 2-3x/week. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of ケトコナゾール?

Reported side effects may include Scalp dryness and irritation, Changes in hair texture, Oily or dry scalp (paradoxical), Contact dermatitis (rare). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for ケトコナゾール and 頭皮乾癬に伴う脱毛?

We rate the evidence as Grade A (Strong Evidence). This rating is based on 2 peer-reviewed studies with 4,586 total participants. The overall direction of effect is positive.

に関する他の成分：頭皮乾癬に伴う脱毛

Curcumin C

ケトコナゾール他の症状・状態について

男性型・女性型脱毛症（AGA） A

総合評価

合計4,586名の参加者を対象とした2件の研究（メタアナリシス1件を含む）に基づく。2件中2件の研究で肯定的な効果が示されている。

Evidence Strength92%

High confidence

研究の内訳

RCT (2)Meta (0)Other (0)

代替成分との比較

この症状に対する他の成分との比較をご覧ください。

に関するすべての成分を見る：頭皮乾癬に伴う脱毛

詳しく見る

References

[1] Franchesca D Choi et al.. J Dermatolog Treat. 2019. Topical ketoconazole: a systematic review of current dermatological applications and future developments. doi:10.1080/09546634.2019.1573309 PubMed
[2] Jeremy Udkoff et al.. Dermatol Ther (Heidelb). 2016. Severe Infliximab-Induced Alopecia and Scalp Psoriasis in a Woman with Crohn's Disease: Dramatic Improvement after Drug Discontinuation and Treatment with … doi:10.1007/s13555-016-0156-z PubMed
[3] J-P Ortonne et al.. Br J Dermatol. 2011. Efficacious and safe management of moderate to severe scalp seborrhoeic dermatitis using clobetasol propionate shampoo 0·05% combined with ketoconazole shampoo … doi:10.1111/j.1365-2133.2011.10269.x PubMed
[4] Ju Jiang et al.. J Dermatol. 2005. Topical application of ketoconazole stimulates hair growth in C3H/HeN mice. doi:10.1111/j.1346-8138.2005.tb00756.x PubMed
[5] A Prakash et al.. Drugs. 1998. Topical mometasone. A review of its pharmacological properties and therapeutic use in the treatment of dermatological disorders. doi:10.2165/00003495-199855010-00009 PubMed
[6] P M Farr et al.. Lancet. 1985. Response of scalp psoriasis to oral ketoconazole. doi:10.1016/s0140-6736(85)90853-0 PubMed

FDAに関する免責事項: これらの記述は米国食品医薬品局（FDA）による評価を受けていません。本ウェブサイトの製品および情報は、疾病の診断、治療、治癒、または予防を目的としたものではありません。表示されているエビデンスグレードは、公開された査読済み研究の分析に基づいており、医療上の助言を構成するものではありません。サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。