Cafeína (Tópica) para Alopecia Androgenética

Baseado em 9 estudos (1 RCT) com 62 participantes no total. 8/9 estudos mostram efeitos positivos.

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Conclusão

Topical caffeine shows promising early evidence for supporting hair growth in androgenetic alopecia, but the research base is still small and more large-scale human trials are needed.

8 out of 9 studies report positive effects on hair growth
Caffeine may work by counteracting DHT's negative effects on hair follicles
One RCT showed improved hair density with a caffeine-containing topical product
The total participant pool is very small (62 people), limiting the strength of conclusions

Key Study Findings

review Single-blind

Do Non-Prescription Products Help in Managing Androgenic Alopecia?

Dose: Various non-prescription agents: procyanidin, cetirizine, caffeine, Oryza sativa bran, pumpkin seed vs: Placebo Efeito: Considerable improvements in one or more parameters across 13 included studies None

Review

A Canadian Consensus on Androgenetic Alopecia: Approach and Management.

Dose: None vs: Placebo Efeito: None None

laboratory/in vitro 26 weeks

Personalized Compounded Hair Loss Treatments: A Compatibility Assessment of the TrichoConcept™ Vehicle Line.

Dose: F1: biotin 0.5%, caffeine 2.0%, niacinamide 2.0%; F2: finasteride 0.1%, minoxidil 1.0%, tretinoin 0. vs: Placebo Efeito: F1 and F3 stable for 180 days; F2 stable for 14 days; F4 and F5 stable for 150 days; F6/F7 stable fo None

review

[Nutrition in improving sleep quality and fighting insomnia].

Dose: tryptophan, carbohydrates, omega-3, vitamins (B6, B12, folate, niacin, D, C, beta-carotene), mineral vs: Placebo Efeito: None None

review

Complementary and alternative supplements: a review of dermatologic effectiveness for androgenetic alopecia.

Dose: various CAMs: pumpkin seed oil, saw palmetto, melatonin extract, caffeine extract, rosemary oil vs: Placebo Efeito: several CAMs effective vs baseline or minoxidil with minimal side effects None

animal experimental study

Sleep-promoting activity of amylase-treated Ashwagandha (Withania somnifera L. Dunal) root extract via GABA receptors.

Dose: dose-dependent (specific doses not reported in abstract) vs: Placebo Efeito: None None

Key Statistics

Estudos

Participantes

↑

Positive

Nota

Referenced Papers

A Canadian Consensus on Androgenetic Alopecia: Approach and Management. Other

Journal of cutaneous … 2025 2 citações

Do Non-Prescription Products Help in Managing Androgenic Alopecia? Review

Skin appendage disorders 2025 1 citações

Personalized Compounded Hair Loss Treatments: A Compatibility Assessment of the TrichoConcept™ Vehicle Line. Other

International journal of … 2025

[Nutrition in improving sleep quality and fighting insomnia]. Review

Nutricion hospitalaria 2025

Complementary and alternative supplements: a review of dermatologic effectiveness for androgenetic alopecia. Review

Proceedings (Baylor University. … 2024 14 citações

Sleep-promoting activity of amylase-treated Ashwagandha (Withania somnifera L. Dunal) root extract via GABA receptors. Other

Journal of food … 2023 17 citações

Natural products for male androgenetic alopecia. Review

Dermatologic therapy 2022 41 citações

Reduction of telogen rate and increase of hair density in androgenetic alopecia by a cosmetic product: Results of a randomized, … RCT

Journal of cosmetic … 2022 11 citações

Evidence for supplemental treatments in androgenetic alopecia. Other

Journal of drugs … 2014 26 citações

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosagens Comumente Utilizadas

topical:: 0.2% caffeine shampoo or serum

Limite superior: Topical only

Dosagens Estudadas em Pesquisas

Dosagem	Duração	Efeito	N
Various non-prescription agents: procyanidin, cetirizine, caffeine, Oryza sativa bran, pumpkin seed	--	Positive	--
None	--	Positive	--
F1: biotin 0.5%, caffeine 2.0%, niacinamide 2.0%; F2: finasteride 0.1%, minoxidil 1.0%, tretinoin 0.	26 weeks	Positive	--
tryptophan, carbohydrates, omega-3, vitamins (B6, B12, folate, niacin, D, C, beta-carotene), mineral	--	Positive	--
various CAMs: pumpkin seed oil, saw palmetto, melatonin extract, caffeine extract, rosemary oil	--	Positive	--
dose-dependent (specific doses not reported in abstract)	--	Positive	--
None	--	Positive	--
foam applied twice daily containing nicotinic acid hexyl ester, polyphenols, zinc, glycine, and caff	26 weeks	Positive	62

Melhor horário: Apply shampoo or serum to scalp, leave on for 2 minutes before rinsing

Safety & Side Effects

Efeitos Colaterais Relatados

⚠ Scalp irritation or dryness
⚠ Minimal systemic absorption (low risk of systemic effects)
⚠ Contact sensitization (rare)

Interações Conhecidas

● Minoxidil (may be used in combination; no significant interaction)
● Other topical scalp products (apply at separate times)

Ingestão máxima tolerável: Topical only

Consulte sempre o seu profissional de saúde antes de iniciar qualquer suplemento.Sempre consulte seu profissional de saúde antes de iniciar qualquer suplemento.

Frequently Asked Questions

Does Cafeína (Tópica) help with Alopecia Androgenética?

Based on 9 studies with 62 participants, there is moderate evidence from clinical studies that Cafeína (Tópica) may support Alopecia Androgenética management. Our evidence grade is B (Good Evidence).

How much Cafeína (Tópica) should I take for Alopecia Androgenética?

Studies have used various dosages. A commonly studied range is 0.2% caffeine shampoo or serum. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Cafeína (Tópica)?

Reported side effects may include Scalp irritation or dryness, Minimal systemic absorption (low risk of systemic effects), Contact sensitization (rare). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Cafeína (Tópica) and Alopecia Androgenética?

We rate the evidence as Grade B (Good Evidence). This rating is based on 9 peer-reviewed studies with 62 total participants. The overall direction of effect is positive.

Related Evidence

Outros ingredientes para Alopecia Androgenética

Minoxidil A Finasteride A Terapia PRP A Dutasteride A Ácidos graxos ômega-3 A Microagulhamento A

Veredito Rápido

Baseado em 9 estudos (1 RCT) com 62 participantes no total. 8/9 estudos mostram efeitos positivos.

Evidence Strength72%

High confidence

Detalhamento dos Estudos

RCT (1)Meta (0)Other (8)

Comparar Alternativas

Veja como outros ingredientes se comparam para esta condição.

Ver todos os ingredientes para Alopecia Androgenética

Saiba Mais

Aviso Legal da FDA: Estas declarações não foram avaliadas pela Food and Drug Administration. Os produtos e informações neste site não se destinam a diagnosticar, tratar, curar ou prevenir qualquer doença. As notas de evidência apresentadas são baseadas em nossa análise de pesquisas revisadas por pares publicadas e não constituem aconselhamento médico. Sempre consulte seu profissional de saúde antes de iniciar qualquer regime de suplementação.