케라틴 관련 노화성 모발 가늘어짐

총 495명의 참여자를 대상으로 한 32건의 연구(RCT 5건)에 근거합니다. 32건 중 21건의 연구에서 긍정적인 효과가 나타났습니다.

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결론

Keratin supplements show good evidence for supporting hair growth in age-related thinning, with multiple RCTs reporting positive results, though the research includes a mix of direct and indirect evidence.

21 out of 32 studies show positive effects, including 5 randomized controlled trials
Annurca apple-derived keratin formulations have shown particularly promising results in RCTs
Keratin-related signaling pathways are well-established as important for hair follicle health
Some evidence is from laboratory studies, so real-world effectiveness may vary

Key Study Findings

Other

TBG096 stimulates hair regeneration through IGF-1R-mediated angiogenesis.

Dose: None vs: untreated controls Outcome: hair follicle transition from telogen to anagen phase 효과: None None

대상 집단: female and male rats, naturally aged and DHT-induced alopecia model mice

in vitro/ex vivo study

A proprietary lipidosterolic extract of Serenoa repens promotes hair growth through mechanisms that extend beyond …

Dose: USPlus DERM (lipidosterolic extract of Serenoa repens) at 0.4 and 10 μg/mL in hair follicle organ cu vs: Placebo 효과: USPlus DERM IC50=0.39 μg/mL (vs 29.1 μg/mL standard extract); 0.4 μg/mL significantly reduced melani None

Animal/Laboratory Study

IKZF1 and Ikaros Overexpression Results in Alopecia Areata-Like Phenotype in Mice.

Dose: Corticosteroid injections (dose not specified) in transgenic mice vs: Placebo 효과: None None

Observational Study n=144 Open-label

Alternative and Complimentary Medication Use in Singers: A Pilot Survey.

Dose: None vs: None Outcome: Self-reported use patterns and perceived vocal effects 효과: None None

대상 집단: Singers with varying singing styles, mean age 51.8y

Review

B-vitamins and one-carbon metabolism during pregnancy: health impacts and challenges.

Dose: None vs: None Outcome: Pregnancy outcomes and offspring neurodevelopment 효과: None None

대상 집단: Pregnant women (review)

Review

Cannabidiol (CBD) as an emerging nutraceutical ingredient from industrial hemp: regulation, production, extraction, nutraceutical properties, …

Dose: None vs: None Outcome: CBD food applications and functional properties 효과: None None

대상 집단: General population (review of CBD in food industry)

Key Statistics

연구

6199

참여자

↔

Mixed

등급

Referenced Papers

TBG096 stimulates hair regeneration through IGF-1R-mediated angiogenesis. Other

Biochemical pharmacology 2026

Cannabidiol (CBD) as an emerging nutraceutical ingredient from industrial hemp: regulation, production, extraction, nutraceutical properties, and functionality. Review

Critical reviews in … 2025 5 인용

B-vitamins and one-carbon metabolism during pregnancy: health impacts and challenges. Review

The Proceedings of … 2025 5 인용

Alternative and Complimentary Medication Use in Singers: A Pilot Survey. Other

Journal of voice … 2025 2 인용

IKZF1 and Ikaros Overexpression Results in Alopecia Areata-Like Phenotype in Mice. Other

Experimental dermatology 2025 2 인용

A proprietary lipidosterolic extract of Serenoa repens promotes hair growth through mechanisms that extend beyond 5-alpha reductase inhibition: Insights from … Other

International journal of … 2025 1 인용

Tolerability of long-term cannabidiol supplementation to healthy adult dogs. RCT

Journal of veterinary … 2024 19 인용

Effects of vitamins and polyunsaturated fatty acids on cognitive function in older adults with mild cognitive impairment: a meta-analysis of … Meta-Analysis

European journal of … 2024 16 인용

Safety study of cannabidiol products in healthy dogs. Other

Frontiers in veterinary … 2024 11 인용

Dietary Clostridium butyricum and 25-Hydroxyvitamin D3 modulate bone metabolism of broilers through the gut-brain axis. Other

Poultry science 2024 9 인용

Does Vitamin B6 Act as an Exercise Mimetic in Skeletal Muscle? Review

International journal of … 2024 5 인용

Does a broad-spectrum cannabidiol supplement improve performance in a 10-min cycle ergometer performance-test? RCT

European journal of … 2024 4 인용

Prevalence of Dietary Modification and Supplement Use in Patients with Metastatic Renal Cell Carcinoma Receiving Systemic Therapy. Other

Nutrients 2024 2 인용

Cannabidiol can affect morphology, morphometry, enzymatic and microbial activity of rabbit digestive system. Other

Journal of animal … 2024

The Role of One-Carbon Metabolism in Healthy Brain Aging. Review

Nutrients 2023 9 인용

Reply to "Vitamin D status in scarring and nonscarring alopecia". Other

Journal of the … 2022 6 인용

Acceptability of cannabidiol in patients with psychosis. Other

Therapeutic advances in … 2022 4 인용

Role of vitamin D in hair loss: A short review. Review

Journal of cosmetic … 2021 44 인용

Feeding Cannabidiol (CBD)-Containing Treats Did Not Affect Canine Daily Voluntary Activity. Other

Frontiers in veterinary … 2021 26 인용

Nutrient intakes from supplement and factors associated with supplement use among breast cancer survivors: A cross-sectional study. Other

European journal of … 2021 5 인용

Topical L-thyroxine: The Cinderella among hormones waiting to dance on the floor of dermatological therapy? Review

Experimental dermatology 2020 10 인용

Vitamin D Receptor Gene Polymorphisms Taq-1 and Cdx-1 in Female Pattern Hair Loss. Other

Indian journal of … 2020 5 인용

Hepatotoxicity of a Cannabidiol-Rich Cannabis Extract in the Mouse Model. Other

Molecules (Basel, Switzerland) 2019 137 인용

Decarbonylation: A metabolic pathway of cannabidiol in humans. Other

Drug testing and … 2019 31 인용

Folic acid supplement use and breast cancer risk in BRCA1 and BRCA2 mutation carriers: a case-control study. Other

Breast cancer research … 2019 25 인용

Vitamin D Receptor Gene Polymorphism In Chronic Telogen Effluvium; A Case-Control Study. Other

Clinical, cosmetic and … 2019 7 인용

Comparative evaluation between two nutritional supplements in the improvement of telogen effluvium. Other

Clinical, cosmetic and … 2018 16 인용

Vitamin D Level in Alopecia Areata. Other

Indian journal of … 2017 46 인용

Correspondence of folate dietary intake and biomarker data. Other

The American journal … 2017 34 인용

Zinc and skin biology. Review

Archives of biochemistry … 2016 124 인용

Assessment of vitamin D receptors in alopecia areata and androgenetic alopecia. Other

Journal of cosmetic … 2016 43 인용

[Folate metabolism--epigenetic role of choline and vitamin B12 during pregnancy]. Review

Ginekologia polska 2015 7 인용

Folic acid supplementation with and without vitamin B6 and revascularization risk: a meta-analysis of randomized controlled trials. Meta-Analysis

Clinical nutrition (Edinburgh, … 2014 12 인용

Effect of folate supplementation on folate status and health outcomes in infants, children and adolescents: a systematic review. Systematic Review

International journal of … 2012 19 인용

Inhibition of inflammatory gene expression in keratinocytes using a composition containing carnitine, thioctic Acid and saw palmetto extract. Other

Evidence-based complementary and … 2011 27 인용

[Vitamin B6 (Pyridoxine)--excessive dosage in food supplements and OTC medications]. Review

Harefuah 2004

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

일반적으로 사용되는 용량

hairloss:: 500 mg/day

상한량: Not established

연구에서 사용된 용량

용량	기간	효과	N
None	--	Positive	--
USPlus DERM (lipidosterolic extract of Serenoa repens) at 0.4 and 10 μg/mL in hair follicle organ cu	--	Positive	--
Corticosteroid injections (dose not specified) in transgenic mice	--	Positive	--
None	--	Neutral	144
None	--	Positive	--
None	--	Positive	--
None	--	Neutral	--
5 or 10 mg/kg BW/day	36 weeks	Neutral	18

권장 복용 시간: With meals for better absorption

Safety & Side Effects

보고된 부작용

⚠ Generally well tolerated
⚠ Mild gastrointestinal discomfort in some individuals
⚠ Rare allergic reactions

알려진 상호작용

● No significant drug interactions established
● May interact with protein absorption in individuals with digestive disorders

일일 최대 섭취 허용량: Not established

건강기능식품을 복용하기 전에 반드시 의료 전문가와 상담하십시오.

Frequently Asked Questions

Does 케라틴 help with 노화성 모발 가늘어짐?

Based on 36 studies with 6,199 participants, there is strong evidence from multiple clinical trials that 케라틴 may support 노화성 모발 가늘어짐 management. Our evidence grade is A (Strong Evidence).

How much 케라틴 should I take for 노화성 모발 가늘어짐?

Studies have used various dosages. A commonly studied range is 500 mg/day. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of 케라틴?

Reported side effects may include Generally well tolerated, Mild gastrointestinal discomfort in some individuals, Rare allergic reactions. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for 케라틴 and 노화성 모발 가늘어짐?

We rate the evidence as Grade A (Strong Evidence). This rating is based on 36 peer-reviewed studies with 6,199 total participants. The overall direction of effect is mixed.

Related Evidence

케라틴 다른 건강 상태에 대한 근거

휴지기 탈모 B

한눈에 보기

총 495명의 참여자를 대상으로 한 32건의 연구(RCT 5건)에 근거합니다. 32건 중 21건의 연구에서 긍정적인 효과가 나타났습니다.

Evidence Strength92%

High confidence

연구 분석

RCT (2)Meta (2)Other (32)

대안 비교

이 건강 상태에 대한 다른 성분의 비교 결과를 확인하세요.

모든 성분 보기: 노화성 모발 가늘어짐

자세히 알아보기

FDA 면책 조항: 이 내용은 미국 식품의약국(FDA)의 평가를 받지 않았습니다. 이 웹사이트의 제품 및 정보는 질병의 진단, 치료, 완치 또는 예방을 목적으로 하지 않습니다. 제시된 근거 등급은 발표된 동료 심사 연구에 대한 우리의 분석에 기반하며, 의학적 조언을 구성하지 않습니다. 건강기능식품 복용을 시작하기 전에 반드시 의료 전문가와 상담하십시오.