ビオチン ： 栄養不足による脱毛症
B合計134名の参加者を対象とした10件の研究（RCT 2件を含む）に基づく。10件中6件の研究で肯定的な効果が示されている。
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B
結論
Biotin may help support hair regrowth when hair loss is related to a nutritional deficiency, but the evidence is moderate and works best when an actual biotin deficiency is confirmed.
- 6 out of 10 studies show positive effects of biotin on nutritional deficiency-related hair loss
- Most supportive evidence comes from cases where biotin deficiency was confirmed through blood tests
- The total participant pool is small (134 people), so results should be interpreted with caution
- Biotin is generally well-tolerated, but may interfere with certain lab test results
Key Study Findings
Review
Safety First: A Comprehensive Review of Nutritional Supplements for Hair Loss in Breast Cancer Patients.
Dose: None
vs: Placebo
効果: None
None
narrative review
Addressing the Root Causes of Female Hair Loss and Non-Pharmaceutical Interventions.
Dose: None
vs: Placebo
効果: None
None
laboratory/in vitro
26 weeks
Personalized Compounded Hair Loss Treatments: A Compatibility Assessment of the TrichoConcept™ Vehicle Line.
Dose: F1: biotin 0.5%, caffeine 2.0%, niacinamide 2.0%; F2: finasteride 0.1%, minoxidil 1.0%, tretinoin 0.
vs: Placebo
効果: F1 and F3 stable for 180 days; F2 stable for 14 days; F4 and F5 stable for 150 days; F6/F7 stable fo
None
RCT
n=54
12 weeks
A Comparative Study of Topical Procapil With Platelet-Rich Plasma Therapy Versus Topical Redensyl, Saw Palmetto, …
Dose: Group A: Procapil + PRP (3-week intervals, 4 sessions); Group B: Redensyl + Saw Palmetto + Biotin +
vs: Placebo
効果: significant difference in AGA grading score between groups (Group B superior); p < 0.05
<0.05
narrative review
Valproate-associated hair abnormalities: Pathophysiology and management strategies.
Dose: not specified
vs: Placebo
効果: None
None
case-control study
n=80
Biotin Deficiency in Telogen Effluvium: Fact or Fiction?
Dose: None
vs: Placebo
効果: None
None
Key Statistics
10
研究数
134
参加者数
↑
Positive
B
グレード
Referenced Papers
Nutrients
2025
2 件の引用
International journal of …
2025
Journal of drugs …
2025
Cureus
2023
9 件の引用
Human psychopharmacology
2022
7 件の引用
The Journal of …
2020
7 件の引用
Comparative evaluation between two nutritional supplements in the improvement of telogen effluvium.
Other
Clinical, cosmetic and …
2018
16 件の引用
International journal of …
2016
89 件の引用
Journal of drugs …
2014
26 件の引用
Clinics in dermatology
2010
98 件の引用
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
一般的な使用量
- general:
- 30 mcg/day
- hairloss:
- 2,500-5,000 mcg/day
上限量： No established UL (water-soluble)
研究で検討された用量
| 用量 | 期間 | 効果 | N |
|---|---|---|---|
| None | -- | Mixed | -- |
| None | -- | Positive | -- |
| F1: biotin 0.5%, caffeine 2.0%, niacinamide 2.0%; F2: finasteride 0.1%, minoxidil 1.0%, tretinoin 0. | 26 weeks | Positive | -- |
| Group A: Procapil + PRP (3-week intervals, 4 sessions); Group B: Redensyl + Saw Palmetto + Biotin + | 12 weeks | Positive | 54 |
| not specified | -- | Positive | -- |
| None | -- | Neutral | 80 |
| recommended daily intake amounts; taken orally for 180 days | 26 weeks | Positive | -- |
| None | -- | Mixed | -- |
推奨摂取タイミング： With meals for better absorption
Safety & Side Effects
報告されている副作用
- ⚠ May interfere with laboratory test results (troponin, thyroid panels)
- ⚠ Rare skin rashes at high doses
- ⚠ Mild gastrointestinal discomfort
- ⚠ Potential acne breakouts at doses above 5,000 mcg
既知の相互作用
- ● Anticonvulsants (carbamazepine, phenytoin) may reduce biotin levels
- ● Raw egg whites (avidin) bind biotin and reduce absorption
- ● Prolonged antibiotic use may deplete gut bacterial biotin synthesis
耐容上限摂取量： No established UL (water-soluble)
サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。
Frequently Asked Questions
Does ビオチン help with 栄養不足による脱毛症?
Based on 10 studies with 134 participants, there is moderate evidence from clinical studies that ビオチン may support 栄養不足による脱毛症 management. Our evidence grade is B (Good Evidence).
How much ビオチン should I take for 栄養不足による脱毛症?
Studies have used various dosages. A commonly studied range is 30 mcg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of ビオチン?
Reported side effects may include May interfere with laboratory test results (troponin, thyroid panels), Rare skin rashes at high doses, Mild gastrointestinal discomfort, Potential acne breakouts at doses above 5,000 mcg. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for ビオチン and 栄養不足による脱毛症?
We rate the evidence as Grade B (Good Evidence). This rating is based on 10 peer-reviewed studies with 134 total participants. The overall direction of effect is positive.
Related Evidence
FDAに関する免責事項: これらの記述は米国食品医薬品局（FDA）による評価を受けていません。本ウェブサイトの製品および情報は、疾病の診断、治療、治癒、または予防を目的としたものではありません。表示されているエビデンスグレードは、公開された査読済み研究の分析に基づいており、医療上の助言を構成するものではありません。サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。