Micro-aiguilles pour Alopecia Areata
ABasé sur 32 études (1 meta-analysis, 9 RCTs) avec 1,908 participants au total. 25/32 études montrent des effets positifs.
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A
En conclusion
Microneedling has strong evidence for supporting hair regrowth in alopecia areata, especially when combined with topical medications, and is backed by multiple randomized controlled trials.
- 25 out of 32 studies show positive effects, with 9 RCTs providing robust evidence
- Works by creating micro-injuries that stimulate healing responses and improve drug absorption
- Most effective when combined with topical agents like corticosteroids or vitamin D3
- Both professional clinical procedures and at-home derma rollers have been studied
Key Study Findings
scoping_review
n=16
A Scoping Review of Exosome Delivery Applications in Hair Loss.
Dose: variable; exosomes predominantly from mesenchymal stem cells (MSCs)
vs: Placebo
Effet: None
None
retrospective cohort
n=7
Open-label
Combination Therapy With CGF and Microneedling-Assisted Compound Betamethasone for Resistant Alopecia Areata: A Pilot Study.
Dose: Concentrated growth factor (CGF) combined with microneedling-assisted compound betamethasone; multip
vs: Placebo
Effet: 85.7% achieved complete recovery; 14.3% achieved >50% regrowth; significant SALT score improvement
None
Review
Technological Advances in Anti-hair Loss and Hair Regrowth Cosmeceuticals: Mechanistic Breakthroughs and Industrial Prospects Driven …
Dose: None
vs: Placebo
Effet: None
None
randomized controlled trial
n=24
18 weeks
Open-label
A Comparative Clinical and Trichoscopic Study Between Fractional Radiofrequency Microneedling Versus Intralesional Steroids in Treatment …
Dose: Fractional radiofrequency microneedling (FRM), 6 sessions with 3-week intervals
vs: Placebo
Effet: Comparable efficacy between FRM and ILCS; nonsignificant differences in trichoscopic scores, PGA, an
None
review
The role of microtrauma in hair regrowth and regeneration in non-scarring alopecia.
Dose: Various microtrauma procedures: microneedling, fractional/non-fractional lasers, contact immunothera
vs: Placebo
Effet: Positive outcomes reported for hair density and thickness with microneedling, lasers, LLLT, and PRP
None
animal study
2 weeks
Investigating the potential mechanism of microneedling in alopecia areata mice based on 16S rRNA sequencing …
Dose: Halometasone topical applied every 2 days for 2 weeks after hand-held dermal microneedling treatment
vs: Placebo
Effet: Microneedling enhanced hair growth; restored gut microbiome diversity; reduced acetic acid and propa
None
Key Statistics
34
Études
1908
Participants
↑
Positive
A
Note
Referenced Papers
Cureus
2025
7 citations
Aesthetic plastic surgery
2025
2 citations
Journal of cosmetic …
2025
1 citations
Italian journal of …
2025
Dermatology reports
2025
Dermatologic surgery : …
2025
Frontiers in microbiology
2025
Lasers in medical …
2024
10 citations
Skin appendage disorders
2024
5 citations
PloS one
2024
4 citations
Skin research and …
2024
3 citations
The Journal of …
2024
2 citations
Journal of cosmetic …
2023
8 citations
Clinical, cosmetic and …
2023
3 citations
Dermatology and therapy
2022
43 citations
Archives of dermatological …
2022
16 citations
Efficacy of intradermal minoxidil 5% injections for treatment of patchy non-severe alopecia areata.
RCT
The Journal of …
2022
9 citations
Dermatologic therapy
2022
9 citations
Microneedling combined with compound betamethasone in treatment of severe alopecia areata: A case report.
Case Report
Frontiers in immunology
2022
8 citations
Dermatologic therapy
2022
8 citations
International journal of …
2022
1 citations
Aesthetic plastic surgery
2021
8 citations
Dermatologic therapy
2021
7 citations
Clinical and experimental …
2020
27 citations
Acta dermatovenerologica Alpina, …
2020
24 citations
Journal of the …
2020
10 citations
Proceedings (Baylor University. …
2020
8 citations
Successful Treatment of Alopecia Areata Patches with Triamcinolone Acetonide Using MMP®: Report of 2 Cases.
Case Report
Skin appendage disorders
2020
6 citations
Cureus
2019
18 citations
Journal of cosmetic …
2019
14 citations
Journal of the …
2018
114 citations
The journal of …
2018
25 citations
The Journal of …
2017
1 citations
Journal of cutaneous …
2014
80 citations
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Posologies couramment utilisées
- hairloss:
- 1.5 mm depth, weekly sessions
Limite supérieure : Not applicable
Posologies étudiées dans la recherche
| Posologie | Durée | Effet | N |
|---|---|---|---|
| variable; exosomes predominantly from mesenchymal stem cells (MSCs) | -- | Positive | 16 |
| Concentrated growth factor (CGF) combined with microneedling-assisted compound betamethasone; multip | -- | Positive | 7 |
| None | -- | Mixed | -- |
| Fractional radiofrequency microneedling (FRM), 6 sessions with 3-week intervals | 18 weeks | Neutral | 24 |
| Various microtrauma procedures: microneedling, fractional/non-fractional lasers, contact immunothera | -- | Positive | -- |
| Halometasone topical applied every 2 days for 2 weeks after hand-held dermal microneedling treatment | 2 weeks | Positive | -- |
| Microinfusion of medications into the skin (MMP) using tattoo devices; various drugs (minoxidil, ste | -- | Positive | -- |
| Melatonin 3 mg/kg; PBM diode laser 660nm, 100mW, 3 J/point, 2 sessions/week | 12 weeks | Mixed | 60 |
Moment optimal de prise : Weekly sessions; avoid minoxidil for 24 hours post-treatment
Safety & Side Effects
Effets indésirables signalés
- ⚠ Scalp redness and inflammation (24-72 hours)
- ⚠ Mild bleeding at treatment site
- ⚠ Scalp tenderness and soreness
- ⚠ Rare: infection if proper sterilization not maintained
Interactions connues
- ● Topical minoxidil (enhanced absorption; wait 24 hours after microneedling to apply)
- ● Blood thinners (may increase bleeding during procedure)
- ● Topical retinoids (discontinue 3-5 days before treatment)
Apport maximal tolérable : Not applicable
Consultez toujours votre professionnel de santé avant de commencer tout complément alimentaire.Consultez toujours votre professionnel de santé avant de commencer tout complément alimentaire.
Frequently Asked Questions
Does Micro-aiguilles help with Alopecia Areata?
Based on 34 studies with 1,908 participants, there is strong evidence from multiple clinical trials that Micro-aiguilles may support Alopecia Areata management. Our evidence grade is A (Strong Evidence).
How much Micro-aiguilles should I take for Alopecia Areata?
Studies have used various dosages. A commonly studied range is 1.5 mm depth, weekly sessions. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Micro-aiguilles?
Reported side effects may include Scalp redness and inflammation (24-72 hours), Mild bleeding at treatment site, Scalp tenderness and soreness, Rare: infection if proper sterilization not maintained. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Micro-aiguilles and Alopecia Areata?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 34 peer-reviewed studies with 1,908 total participants. The overall direction of effect is positive.
Related Evidence
Autres ingrédients pour Alopecia Areata
Micro-aiguilles pour d'autres pathologies
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