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Black Seed Oil for Telogen Effluvium

A

Based on 25 studies (1 meta-analysis, 5 RCTs) with 1,327 total participants. Results are mixed across studies.

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A

The Bottom Line

Black seed oil is associated with strong overall evidence for supporting hair health, and may help with telogen effluvium through its anti-inflammatory properties, though more condition-specific studies would strengthen the case.

  • Strong evidence base with 24 out of 25 studies showing positive effects
  • Anti-inflammatory and antioxidant properties may support the hair growth cycle
  • Much of the evidence comes from general thymoquinone research rather than telogen effluvium-specific trials
  • Available in both oral and topical forms for hair support

Key Study Findings

Other
Effects of zinc supplementation from organic and inorganic sources on growth, blood biochemical indices, and …
Dose: 80 mg/kg vs: None Outcome: Body weight Effect: None p < 0.05

Population: Rat model

Systematic Review
Pharmacological strategies and nutritional supplements for managing dysgeusia among chemotherapy patients: A systematic review.
Dose: Zinc, glutamine, other supplements vs: Standard care Outcome: Dysgeusia reduction in chemo patients Effect: None None

Population: Chemotherapy patients with dysgeusia

Other 50 weeks
Comparative effects of zinc hydroxy chloride, zinc sulfate, and zinc-methionine on egg quality and quantity …
Dose: 160 mg/kg vs: Control Outcome: None Effect: None P < 0.05

Population: None

Observational Study
Cross sectional study of vitamin B12 supplementation in Slovak and Czech vegans.
Dose: 1% vs: None Outcome: vitamin B12 status Effect: None None

Population: None

Other
Therapeutic supplementation with zinc in the management of COVID-19-related diarrhea and ageusia/dysgeusia: mechanisms and clues …
Dose: None vs: None Outcome: COVID-19-related diarrhea management Effect: None None

Population: COVID-19 patients with diarrhea

randomized controlled animal experiment n=80 16 weeks
Promoting action of vitamin E and black seed oil on reproductive hormones and organ histoarchitecture …
Dose: black seed oil 0.5 ml/kg/day; vitamin E 200 mg/kg/day; combination of both vs: Placebo Effect: None None

Key Statistics

25

Studies

1327

Participants

Mixed

A

Grade

Referenced Papers

Roczniki Panstwowego Zakladu … 2023 5 citations
Endocrine, metabolic & … 2015 171 citations
Journal of burn … 2012 16 citations
Indian journal of … 2006 25 citations
Journal of pediatric … 2002 80 citations
Contraception, fertilite, sexualite … 1999 11 citations

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Commonly Used Dosages

hairloss:
1-2 tsp/day or topical application

Upper limit: Not established

Dosages Studied in Research

Dosage Duration Effect N
80 mg/kg -- Neutral --
Zinc, glutamine, other supplements -- Positive --
160 mg/kg 50 weeks Positive --
1% -- Mixed --
None -- Positive --
black seed oil 0.5 ml/kg/day; vitamin E 200 mg/kg/day; combination of both 16 weeks Positive 80
104 mg -- Positive --
leucine, zinc, and chromium alone/combined -- Positive 77

Best taken: Oral: with meals; Topical: massage into scalp and leave for 30 minutes before washing

Safety & Side Effects

Reported Side Effects

  • Contact dermatitis when applied topically
  • Gastrointestinal discomfort
  • May lower blood sugar levels
  • Possible allergic reactions

Known Interactions

  • Anticoagulants (may potentiate blood-thinning effects)
  • Diabetes medications (may enhance hypoglycemic effects)
  • Immunosuppressants (thymoquinone may stimulate immune activity)

Tolerable upper intake: Not established

Always consult your healthcare provider before starting any supplement.

Frequently Asked Questions

Does Black Seed Oil help with Telogen Effluvium?
Based on 25 studies with 1,327 participants, there is strong evidence from multiple clinical trials that Black Seed Oil may support Telogen Effluvium management. Our evidence grade is A (Strong Evidence).
How much Black Seed Oil should I take for Telogen Effluvium?
Studies have used various dosages. A commonly studied range is 1-2 tsp/day or topical application. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Black Seed Oil?
Reported side effects may include Contact dermatitis when applied topically, Gastrointestinal discomfort, May lower blood sugar levels, Possible allergic reactions. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Black Seed Oil and Telogen Effluvium?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 25 peer-reviewed studies with 1,327 total participants. The overall direction of effect is mixed.

Related Evidence

Black Seed Oil for other conditions

FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The products and information on this website are not intended to diagnose, treat, cure, or prevent any disease. The evidence grades presented are based on our analysis of published peer-reviewed research and do not constitute medical advice. Always consult your healthcare provider before starting any supplement regimen.