زيت الحبة السوداء لـ تساقط الشعر الكربي (Telogen Effluvium)
A الأدلة تُظهر تجارب سريرية كبيرة متعددة باستمرار فوائد ملحوظة.بناءً على 25 دراسة (4 RCTs) بمشاركة 696 مشاركًا إجمالاً. 24/25 دراسة تُظهر تأثيرات إيجابية.
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A
الخلاصة
Black seed oil is associated with strong overall evidence for supporting hair health, and may help with telogen effluvium through its anti-inflammatory properties, though more condition-specific studies would strengthen the case.
- Strong evidence base with 24 out of 25 studies showing positive effects
- Anti-inflammatory and antioxidant properties may support the hair growth cycle
- Much of the evidence comes from general thymoquinone research rather than telogen effluvium-specific trials
- Available in both oral and topical forms for hair support
Key Study Findings
Other
Effects of zinc supplementation from organic and inorganic sources on growth, blood biochemical indices, and …
Dose: 80 mg/kg
مقابل: None
Outcome: Body weight
التأثير: None
p < 0.05
المجتمع المدروس: Rat model
Systematic Review
Pharmacological strategies and nutritional supplements for managing dysgeusia among chemotherapy patients: A systematic review.
Dose: Zinc, glutamine, other supplements
مقابل: Standard care
Outcome: Dysgeusia reduction in chemo patients
التأثير: None
None
المجتمع المدروس: Chemotherapy patients with dysgeusia
Other
50 weeks
Comparative effects of zinc hydroxy chloride, zinc sulfate, and zinc-methionine on egg quality and quantity …
Dose: 160 mg/kg
مقابل: Control
Outcome: None
التأثير: None
P < 0.05
المجتمع المدروس: None
Observational Study
Cross sectional study of vitamin B12 supplementation in Slovak and Czech vegans.
Dose: 1%
مقابل: None
Outcome: vitamin B12 status
التأثير: None
None
المجتمع المدروس: None
Other
Therapeutic supplementation with zinc in the management of COVID-19-related diarrhea and ageusia/dysgeusia: mechanisms and clues …
Dose: None
مقابل: None
Outcome: COVID-19-related diarrhea management
التأثير: None
None
المجتمع المدروس: COVID-19 patients with diarrhea
randomized controlled animal experiment
n=80
16 weeks
Promoting action of vitamin E and black seed oil on reproductive hormones and organ histoarchitecture …
Dose: black seed oil 0.5 ml/kg/day; vitamin E 200 mg/kg/day; combination of both
مقابل: Placebo
التأثير: None
None
Key Statistics
25
الدراسات
1327
المشاركون
↔
Mixed
A
التقييم
Referenced Papers
The veterinary quarterly
2024
15 اقتباسات
Animal science journal …
2024
3 اقتباسات
Pharmacological strategies and nutritional supplements for managing dysgeusia among chemotherapy patients: A systematic review.
Systematic Review
Clinical nutrition ESPEN
2024
Roczniki Panstwowego Zakladu …
2023
5 اقتباسات
Veterinary medicine and …
2022
7 اقتباسات
Nutrition reviews
2022
3 اقتباسات
Journal of dairy …
2020
58 اقتباسات
Biological trace element …
2017
35 اقتباسات
Zhongguo dang dai …
2016
9 اقتباسات
Endocrine, metabolic & …
2015
171 اقتباسات
British poultry science
2015
98 اقتباسات
Biological trace element …
2015
46 اقتباسات
Journal of burn …
2012
16 اقتباسات
Biological trace element …
2012
Journal of medicinal …
2011
29 اقتباسات
Supplementing iron and zinc: double blind, randomized evaluation of separate or combined delivery.
RCT
European journal of …
2010
51 اقتباسات
Arthritis research & …
2010
17 اقتباسات
Current opinion in …
2009
66 اقتباسات
European journal of …
2009
24 اقتباسات
Molecular biology reports
2007
16 اقتباسات
Indian journal of …
2006
25 اقتباسات
Pharmacology & therapeutics
2005
199 اقتباسات
Metal ions in …
2004
Excessive oral zinc supplementation.
Case Report
Journal of pediatric …
2002
80 اقتباسات
Contraception, fertilite, sexualite …
1999
11 اقتباسات
Cancer detection and …
1998
22 اقتباسات
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
الجرعات الشائعة
- hairloss:
- 1-2 tsp/day or topical application
الحد الأعلى: Not established
الجرعات المدروسة في الأبحاث
| الجرعة | المدة | التأثير | ن |
|---|---|---|---|
| 80 mg/kg | -- | Neutral | -- |
| Zinc, glutamine, other supplements | -- | Positive | -- |
| 160 mg/kg | 50 weeks | Positive | -- |
| 1% | -- | Mixed | -- |
| None | -- | Positive | -- |
| black seed oil 0.5 ml/kg/day; vitamin E 200 mg/kg/day; combination of both | 16 weeks | Positive | 80 |
| 104 mg | -- | Positive | -- |
| leucine, zinc, and chromium alone/combined | -- | Positive | 77 |
أفضل وقت للتناول: Oral: with meals; Topical: massage into scalp and leave for 30 minutes before washing
Safety & Side Effects
الآثار الجانبية المُبلّغ عنها
- ⚠ Contact dermatitis when applied topically
- ⚠ Gastrointestinal discomfort
- ⚠ May lower blood sugar levels
- ⚠ Possible allergic reactions
التفاعلات المعروفة
- ● Anticoagulants (may potentiate blood-thinning effects)
- ● Diabetes medications (may enhance hypoglycemic effects)
- ● Immunosuppressants (thymoquinone may stimulate immune activity)
الحد الأقصى المسموح به: Not established
استشر مقدم الرعاية الصحية دائماً قبل البدء بأي مكمل غذائي.
Frequently Asked Questions
Does زيت الحبة السوداء help with تساقط الشعر الكربي (Telogen Effluvium)?
Based on 25 studies with 1,327 participants, there is strong evidence from multiple clinical trials that زيت الحبة السوداء may support تساقط الشعر الكربي (Telogen Effluvium) management. Our evidence grade is A (Strong Evidence).
How much زيت الحبة السوداء should I take for تساقط الشعر الكربي (Telogen Effluvium)?
Studies have used various dosages. A commonly studied range is 1-2 tsp/day or topical application. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of زيت الحبة السوداء?
Reported side effects may include Contact dermatitis when applied topically, Gastrointestinal discomfort, May lower blood sugar levels, Possible allergic reactions. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for زيت الحبة السوداء and تساقط الشعر الكربي (Telogen Effluvium)?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 25 peer-reviewed studies with 1,327 total participants. The overall direction of effect is mixed.
Related Evidence
مكونات أخرى لـ تساقط الشعر الكربي (Telogen Effluvium)
زيت الحبة السوداء لحالات أخرى
References
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- [2] Ali Afshar Bakeshlo et al.. Anim Sci J. 2024. Comparative effects of zinc hydroxy chloride, zinc sulfate, and zinc-methionine on egg quality and quantity traits in laying hens. doi:10.1111/asj.13996 PubMed
- [3] Beatrice Mazzoleni et al.. Clin Nutr ESPEN. 2024. Pharmacological strategies and nutritional supplements for managing dysgeusia among chemotherapy patients: A systematic review. doi:10.1016/j.clnesp.2024.05.026 PubMed
- [4] Radek Latal et al.. Rocz Panstw Zakl Hig. 2023. Cross sectional study of vitamin B12 supplementation in Slovak and Czech vegans. doi:10.32394/rpzh.2023.0259 PubMed
- [5] Afrina Mustari et al.. Vet Med Sci. 2022. Promoting action of vitamin E and black seed oil on reproductive hormones and organ histoarchitecture of Swiss albino mice. doi:10.1002/vms3.708 PubMed
- [6] Heitor O Santos. Nutr Rev. 2022. Therapeutic supplementation with zinc in the management of COVID-19-related diarrhea and ageusia/dysgeusia: mechanisms and clues for a personalized dosage regimen. doi:10.1093/nutrit/nuab054 PubMed
- [7] M N Chang et al.. J Dairy Sci. 2020. Effects of different types of zinc supplement on the growth, incidence of diarrhea, immune function, and rectal microbiota of newborn … doi:10.3168/jds.2019-17610 PubMed
- [8] Hassan Sadri et al.. Biol Trace Elem Res. 2017. Hypoglycemic and Hypolipidemic Effects of Leucine, Zinc, and Chromium, Alone and in Combination, in Rats with Type 2 Diabetes. doi:10.1007/s12011-017-1014-2 PubMed
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- [12] Abhay Kumar Singh et al.. Biol Trace Elem Res. 2015. Effects of methionine chelate- or yeast proteinate-based supplement of copper, iron, manganese and zinc on broiler growth performance, their distribution … doi:10.1007/s12011-014-0222-2 PubMed
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- [15] Ramiro González Matute et al.. J Med Food. 2011. Copper and zinc bioaccumulation and bioavailability of Ganoderma lucidum. doi:10.1089/jmf.2010.0206 PubMed
- [16] S Chang et al.. Eur J Clin Nutr. 2010. Supplementing iron and zinc: double blind, randomized evaluation of separate or combined delivery. doi:10.1038/ejcn.2009.127 PubMed
- [17] Robin Christensen et al.. Arthritis Res Ther. 2010. Is Phytalgic(R) a goldmine for osteoarthritis patients or is there something fishy about this nutraceutical? A summary of findings and … doi:10.1186/ar2909 PubMed
- [18] Sabine Ellinger et al.. Curr Opin Clin Nutr Metab Care. 2009. Efficacy of vitamin supplementation in situations with wound healing disorders: results from clinical intervention studies. doi:10.1097/MCO.0b013e328331a5b5 PubMed
- [19] J L Rosado et al.. Eur J Clin Nutr. 2009. Interaction of zinc or vitamin A supplementation and specific parasite infections on Mexican infants' growth: a randomized clinical trial. doi:10.1038/ejcn.2009.53 PubMed
- [20] Daoxu Sun et al.. Mol Biol Rep. 2007. Regulation of zinc transporters by dietary zinc supplement in breast cancer. doi:10.1007/s11033-007-9082-6 PubMed
- [21] Abdullah H Baqui et al.. Indian J Pediatr. 2006. Zinc supplementation and serum zinc during diarrhea. doi:10.1007/BF02759893 PubMed
- [22] Peter D Zalewski et al.. Pharmacol Ther. 2005. Zinc metabolism in airway epithelium and airway inflammation: basic mechanisms and clinical targets. A review. doi:10.1016/j.pharmthera.2004.09.004 PubMed
- [23] Paul W Jones et al.. Met Ions Biol Syst. 2004. The use and role of zinc and its compounds in wound healing. PubMed
- [24] Mark B Salzman et al.. J Pediatr Hematol Oncol. 2002. Excessive oral zinc supplementation. doi:10.1097/00043426-200210000-00020 PubMed
- [25] D Bouglé et al.. Contracept Fertil Sex. 1999. [Iron and zinc supplementation during pregnancy: interactions and requirements]. PubMed
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