Microagujación para Alopecia Areata

Basado en 32 estudios (1 meta-analysis, 9 RCTs) con 1,908 participantes en total. 25/32 estudios muestran efectos positivos.

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Conclusión

Microneedling has strong evidence for supporting hair regrowth in alopecia areata, especially when combined with topical medications, and is backed by multiple randomized controlled trials.

25 out of 32 studies show positive effects, with 9 RCTs providing robust evidence
Works by creating micro-injuries that stimulate healing responses and improve drug absorption
Most effective when combined with topical agents like corticosteroids or vitamin D3
Both professional clinical procedures and at-home derma rollers have been studied

Key Study Findings

scoping_review n=16

A Scoping Review of Exosome Delivery Applications in Hair Loss.

Dose: variable; exosomes predominantly from mesenchymal stem cells (MSCs) vs: Placebo Efecto: None None

retrospective cohort n=7 Open-label

Combination Therapy With CGF and Microneedling-Assisted Compound Betamethasone for Resistant Alopecia Areata: A Pilot Study.

Dose: Concentrated growth factor (CGF) combined with microneedling-assisted compound betamethasone; multip vs: Placebo Efecto: 85.7% achieved complete recovery; 14.3% achieved >50% regrowth; significant SALT score improvement None

Review

Technological Advances in Anti-hair Loss and Hair Regrowth Cosmeceuticals: Mechanistic Breakthroughs and Industrial Prospects Driven …

Dose: None vs: Placebo Efecto: None None

randomized controlled trial n=24 18 weeks Open-label

A Comparative Clinical and Trichoscopic Study Between Fractional Radiofrequency Microneedling Versus Intralesional Steroids in Treatment …

Dose: Fractional radiofrequency microneedling (FRM), 6 sessions with 3-week intervals vs: Placebo Efecto: Comparable efficacy between FRM and ILCS; nonsignificant differences in trichoscopic scores, PGA, an None

review

The role of microtrauma in hair regrowth and regeneration in non-scarring alopecia.

Dose: Various microtrauma procedures: microneedling, fractional/non-fractional lasers, contact immunothera vs: Placebo Efecto: Positive outcomes reported for hair density and thickness with microneedling, lasers, LLLT, and PRP None

animal study 2 weeks

Investigating the potential mechanism of microneedling in alopecia areata mice based on 16S rRNA sequencing …

Dose: Halometasone topical applied every 2 days for 2 weeks after hand-held dermal microneedling treatment vs: Placebo Efecto: Microneedling enhanced hair growth; restored gut microbiome diversity; reduced acetic acid and propa None

Key Statistics

Estudios

1908

Participantes

↑

Positive

Calificación

Referenced Papers

A Scoping Review of Exosome Delivery Applications in Hair Loss. Review

Cureus 2025 7 citas

Technological Advances in Anti-hair Loss and Hair Regrowth Cosmeceuticals: Mechanistic Breakthroughs and Industrial Prospects Driven by Multidisciplinary Collaborative Innovation. Review

Aesthetic plastic surgery 2025 2 citas

Combination Therapy With CGF and Microneedling-Assisted Compound Betamethasone for Resistant Alopecia Areata: A Pilot Study. Other

Journal of cosmetic … 2025 1 citas

The role of microtrauma in hair regrowth and regeneration in non-scarring alopecia. Review

Italian journal of … 2025

Microinfusion of medications into the skin as a drug delivery technique: a narrative review. Other

Dermatology reports 2025

A Comparative Clinical and Trichoscopic Study Between Fractional Radiofrequency Microneedling Versus Intralesional Steroids in Treatment of Alopecia Areata. RCT

Dermatologic surgery : … 2025

Investigating the potential mechanism of microneedling in alopecia areata mice based on 16S rRNA sequencing and metabolomics. Other

Frontiers in microbiology 2025

The role of laser and energy-assisted drug delivery in the treatment of alopecia. Review

Lasers in medical … 2024 10 citas

Growth Factors and Microneedling in Alopecia Areata: A Narrative Review. Review

Skin appendage disorders 2024 5 citas

Comparison between melatonin versus melatonin and photobiomodulation versus photobiomodulation in the treatment of Alopecia X in German Spitz dogs: Clinical, … Other

PloS one 2024 4 citas

Effect of minoxidil combined with triamcinolone acetonide on alopecia areata by microneedle injection. Other

Skin research and … 2024 3 citas

Cosmetic filler-induced hair loss: case series and literature review. Case Report

The Journal of … 2024 2 citas

Combined microneedling with topical vitamin D3 or bimatoprost versus microneedling alone in the treatment of alopecia areata: A comparative randomized … RCT

Journal of cosmetic … 2023 8 citas

Efficacy, safety, and Pharmacoeconomics of Three Common Strategies for Pediatric Alopecia Areata Patients: A Retrospective Cohort Study. Other

Clinical, cosmetic and … 2023 3 citas

Microneedling and Its Use in Hair Loss Disorders: A Systematic Review. Review

Dermatology and therapy 2022 43 citas

Clinical efficacy of adipocyte-derived stem cells conditioned media combined with micro-injury in refractory patch of alopecia areata. Other

Archives of dermatological … 2022 16 citas

Efficacy of intradermal minoxidil 5% injections for treatment of patchy non-severe alopecia areata. RCT

The Journal of … 2022 9 citas

Fractional CO2 laser versus microneedling as a transepidermal drug delivery system for the treatment of alopecia areata: A clinical dermoscopic … RCT

Dermatologic therapy 2022 9 citas

Microneedling combined with compound betamethasone in treatment of severe alopecia areata: A case report. Case Report

Frontiers in immunology 2022 8 citas

Comparative study between topical application of triamcinolone acetonide after fractional carbon dioxide laser versus microneedling in the treatment of resistant … RCT

Dermatologic therapy 2022 8 citas

Comparative Efficacy of Injection Triamcinolone Acetonide given Intralesionally and through Microneedling in Alopecia areata. Other

International journal of … 2022 1 citas

Platelet Rich Plasma Hybridized Adipose Transplant (PHAT) for the Treatment of Hair Loss: A Case Series. Review

Aesthetic plastic surgery 2021 8 citas

Superficial cryotherapy using dimethyl ether and propane mixture versus microneedling in the treatment of alopecia areata: A prospective single-blinded randomized … RCT

Dermatologic therapy 2021 7 citas

Combination of photodynamic therapy with 5-aminolaevulinic acid and microneedling in the treatment of alopecia areata resistant to conventional therapies: our … Other

Clinical and experimental … 2020 27 citas

Platelet-rich plasma in alopecia areata: intradermal injection versus topical application with transepidermal delivery via either fractional carbon dioxide laser or … RCT

Acta dermatovenerologica Alpina, … 2020 24 citas

Adverse effects of platelet-rich plasma and microneedling. Other

Journal of the … 2020 10 citas

Ophiasis alopecia areata treated with microneedling. Case Report

Proceedings (Baylor University. … 2020 8 citas

Successful Treatment of Alopecia Areata Patches with Triamcinolone Acetonide Using MMP®: Report of 2 Cases. Case Report

Skin appendage disorders 2020 6 citas

Fractional Laser-assisted Hair Regrowth and Microneedling for the Treatment of Alopecia Areata: A Review. Review

Cureus 2019 18 citas

The rise of transcutaneous drug delivery for the management of alopecia: a review of existing literature and an eye towards … Review

Journal of cosmetic … 2019 14 citas

Microneedling for the treatment of hair loss? Review

Journal of the … 2018 114 citas

An Overview of the Biology of Platelet-Rich Plasma and Microneedling as Potential Treatments for Alopecia Areata. Review

The journal of … 2018 25 citas

WITHDRAWN: An Overview of the Biology of Platelet-Rich Plasma and Microneedling as Potential Treatments for Alopecia Areata. Review

The Journal of … 2017 1 citas

Alopecia areata-successful outcome with microneedling and triamcinolone acetonide. Other

Journal of cutaneous … 2014 80 citas

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosificaciones de uso común

hairloss:: 1.5 mm depth, weekly sessions

Límite superior: Not applicable

Dosificaciones estudiadas en la investigación

Dosificación	Duración	Efecto	N
variable; exosomes predominantly from mesenchymal stem cells (MSCs)	--	Positive	16
Concentrated growth factor (CGF) combined with microneedling-assisted compound betamethasone; multip	--	Positive	7
None	--	Mixed	--
Fractional radiofrequency microneedling (FRM), 6 sessions with 3-week intervals	18 weeks	Neutral	24
Various microtrauma procedures: microneedling, fractional/non-fractional lasers, contact immunothera	--	Positive	--
Halometasone topical applied every 2 days for 2 weeks after hand-held dermal microneedling treatment	2 weeks	Positive	--
Microinfusion of medications into the skin (MMP) using tattoo devices; various drugs (minoxidil, ste	--	Positive	--
Melatonin 3 mg/kg; PBM diode laser 660nm, 100mW, 3 J/point, 2 sessions/week	12 weeks	Mixed	60

Mejor momento para tomar: Weekly sessions; avoid minoxidil for 24 hours post-treatment

Safety & Side Effects

Efectos secundarios reportados

⚠ Scalp redness and inflammation (24-72 hours)
⚠ Mild bleeding at treatment site
⚠ Scalp tenderness and soreness
⚠ Rare: infection if proper sterilization not maintained

Interacciones conocidas

● Topical minoxidil (enhanced absorption; wait 24 hours after microneedling to apply)
● Blood thinners (may increase bleeding during procedure)
● Topical retinoids (discontinue 3-5 days before treatment)

Ingesta máxima tolerable: Not applicable

Consulte siempre a su profesional de salud antes de comenzar cualquier suplemento.Siempre consulte a su profesional de salud antes de comenzar cualquier suplemento.

Frequently Asked Questions

Does Microagujación help with Alopecia Areata?

Based on 34 studies with 1,908 participants, there is strong evidence from multiple clinical trials that Microagujación may support Alopecia Areata management. Our evidence grade is A (Strong Evidence).

How much Microagujación should I take for Alopecia Areata?

Studies have used various dosages. A commonly studied range is 1.5 mm depth, weekly sessions. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Microagujación?

Reported side effects may include Scalp redness and inflammation (24-72 hours), Mild bleeding at treatment site, Scalp tenderness and soreness, Rare: infection if proper sterilization not maintained. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Microagujación and Alopecia Areata?

We rate the evidence as Grade A (Strong Evidence). This rating is based on 34 peer-reviewed studies with 1,908 total participants. The overall direction of effect is positive.

Related Evidence

Otros ingredientes para Alopecia Areata

Minoxidil A Vitamina D A Terapia PRP A Aceite de Semilla Negra A Ginseng C Zinc F

Microagujación para otras condiciones

Alopecia Androgenética A

Veredicto rápido

Basado en 32 estudios (1 meta-analysis, 9 RCTs) con 1,908 participantes en total. 25/32 estudios muestran efectos positivos.

Evidence Strength92%

High confidence

Desglose de estudios

RCT (7)Meta (0)Other (27)

Comparar alternativas

Vea cómo se comparan otros ingredientes para esta condición.

Ver todos los ingredientes para Alopecia Areata

Más información

Aviso legal FDA: Estas declaraciones no han sido evaluadas por la Food and Drug Administration. Los productos y la información en este sitio web no están destinados a diagnosticar, tratar, curar ni prevenir ninguna enfermedad. Las calificaciones de evidencia presentadas se basan en nuestro análisis de investigación publicada revisada por pares y no constituyen consejo médico. Siempre consulte a su profesional de salud antes de comenzar cualquier régimen de suplementos.