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Keratin für Altersbedingte Haarausdünnung

A

Basierend auf 32 Studien (5 RCTs) mit 495 Teilnehmern insgesamt. 21/32 Studien zeigen positive Effekte.

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A

Fazit

Keratin supplements show good evidence for supporting hair growth in age-related thinning, with multiple RCTs reporting positive results, though the research includes a mix of direct and indirect evidence.

  • 21 out of 32 studies show positive effects, including 5 randomized controlled trials
  • Annurca apple-derived keratin formulations have shown particularly promising results in RCTs
  • Keratin-related signaling pathways are well-established as important for hair follicle health
  • Some evidence is from laboratory studies, so real-world effectiveness may vary

Key Study Findings

Other
TBG096 stimulates hair regeneration through IGF-1R-mediated angiogenesis.
Dose: None vs.: untreated controls Outcome: hair follicle transition from telogen to anagen phase Wirkung: None None

Population: female and male rats, naturally aged and DHT-induced alopecia model mice

in vitro/ex vivo study
A proprietary lipidosterolic extract of Serenoa repens promotes hair growth through mechanisms that extend beyond …
Dose: USPlus DERM (lipidosterolic extract of Serenoa repens) at 0.4 and 10 μg/mL in hair follicle organ cu vs.: Placebo Wirkung: USPlus DERM IC50=0.39 μg/mL (vs 29.1 μg/mL standard extract); 0.4 μg/mL significantly reduced melani None
Animal/Laboratory Study
IKZF1 and Ikaros Overexpression Results in Alopecia Areata-Like Phenotype in Mice.
Dose: Corticosteroid injections (dose not specified) in transgenic mice vs.: Placebo Wirkung: None None
Observational Study n=144 Open-label
Alternative and Complimentary Medication Use in Singers: A Pilot Survey.
Dose: None vs.: None Outcome: Self-reported use patterns and perceived vocal effects Wirkung: None None

Population: Singers with varying singing styles, mean age 51.8y

Review
B-vitamins and one-carbon metabolism during pregnancy: health impacts and challenges.
Dose: None vs.: None Outcome: Pregnancy outcomes and offspring neurodevelopment Wirkung: None None

Population: Pregnant women (review)

Review
Cannabidiol (CBD) as an emerging nutraceutical ingredient from industrial hemp: regulation, production, extraction, nutraceutical properties, …
Dose: None vs.: None Outcome: CBD food applications and functional properties Wirkung: None None

Population: General population (review of CBD in food industry)

Key Statistics

36

Studien

6199

Teilnehmer

Mixed

A

Bewertung

Referenced Papers

Frontiers in veterinary … 2024 11 Zitierungen
International journal of … 2024 5 Zitierungen
Therapeutic advances in … 2022 4 Zitierungen
Journal of cosmetic … 2021 44 Zitierungen
Molecules (Basel, Switzerland) 2019 137 Zitierungen
Drug testing and … 2019 31 Zitierungen
Indian journal of … 2017 46 Zitierungen
The American journal … 2017 34 Zitierungen
Archives of biochemistry … 2016 124 Zitierungen

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Übliche Dosierungen

hairloss:
500 mg/day

Obergrenze: Not established

In der Forschung untersuchte Dosierungen

Dosierung Dauer Wirkung N
None -- Positive --
USPlus DERM (lipidosterolic extract of Serenoa repens) at 0.4 and 10 μg/mL in hair follicle organ cu -- Positive --
Corticosteroid injections (dose not specified) in transgenic mice -- Positive --
None -- Neutral 144
None -- Positive --
None -- Positive --
None -- Neutral --
5 or 10 mg/kg BW/day 36 weeks Neutral 18

Beste Einnahmezeit: With meals for better absorption

Safety & Side Effects

Gemeldete Nebenwirkungen

  • Generally well tolerated
  • Mild gastrointestinal discomfort in some individuals
  • Rare allergic reactions

Bekannte Wechselwirkungen

  • No significant drug interactions established
  • May interact with protein absorption in individuals with digestive disorders

Tolerierbare Höchstaufnahmemenge: Not established

Konsultieren Sie immer Ihren Arzt, bevor Sie ein Nahrungsergänzungsmittel einnehmen.Konsultieren Sie immer Ihren Arzt, bevor Sie ein Nahrungsergänzungsmittel einnehmen.

Frequently Asked Questions

Does Keratin help with Altersbedingte Haarausdünnung?
Based on 36 studies with 6,199 participants, there is strong evidence from multiple clinical trials that Keratin may support Altersbedingte Haarausdünnung management. Our evidence grade is A (Strong Evidence).
How much Keratin should I take for Altersbedingte Haarausdünnung?
Studies have used various dosages. A commonly studied range is 500 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Keratin?
Reported side effects may include Generally well tolerated, Mild gastrointestinal discomfort in some individuals, Rare allergic reactions. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Keratin and Altersbedingte Haarausdünnung?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 36 peer-reviewed studies with 6,199 total participants. The overall direction of effect is mixed.

Related Evidence

Keratin für andere Beschwerden

FDA-Haftungsausschluss: Diese Aussagen wurden nicht von der Food and Drug Administration bewertet. Die Produkte und Informationen auf dieser Website sind nicht dazu bestimmt, Krankheiten zu diagnostizieren, zu behandeln, zu heilen oder zu verhindern. Die dargestellten Evidenzbewertungen basieren auf unserer Analyse veröffentlichter begutachteter Forschung und stellen keine medizinische Beratung dar. Konsultieren Sie immer Ihren Arzt, bevor Sie mit der Einnahme von Nahrungsergänzungsmitteln beginnen.