Koffein (topisch) für Androgenetische Alopezie

Basierend auf 9 Studien (1 RCT) mit 62 Teilnehmern insgesamt. 8/9 Studien zeigen positive Effekte.

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Fazit

Topical caffeine shows promising early evidence for supporting hair growth in androgenetic alopecia, but the research base is still small and more large-scale human trials are needed.

8 out of 9 studies report positive effects on hair growth
Caffeine may work by counteracting DHT's negative effects on hair follicles
One RCT showed improved hair density with a caffeine-containing topical product
The total participant pool is very small (62 people), limiting the strength of conclusions

Key Study Findings

review Single-blind

Do Non-Prescription Products Help in Managing Androgenic Alopecia?

Dose: Various non-prescription agents: procyanidin, cetirizine, caffeine, Oryza sativa bran, pumpkin seed vs.: Placebo Wirkung: Considerable improvements in one or more parameters across 13 included studies None

Review

A Canadian Consensus on Androgenetic Alopecia: Approach and Management.

Dose: None vs.: Placebo Wirkung: None None

laboratory/in vitro 26 weeks

Personalized Compounded Hair Loss Treatments: A Compatibility Assessment of the TrichoConcept™ Vehicle Line.

Dose: F1: biotin 0.5%, caffeine 2.0%, niacinamide 2.0%; F2: finasteride 0.1%, minoxidil 1.0%, tretinoin 0. vs.: Placebo Wirkung: F1 and F3 stable for 180 days; F2 stable for 14 days; F4 and F5 stable for 150 days; F6/F7 stable fo None

review

[Nutrition in improving sleep quality and fighting insomnia].

Dose: tryptophan, carbohydrates, omega-3, vitamins (B6, B12, folate, niacin, D, C, beta-carotene), mineral vs.: Placebo Wirkung: None None

review

Complementary and alternative supplements: a review of dermatologic effectiveness for androgenetic alopecia.

Dose: various CAMs: pumpkin seed oil, saw palmetto, melatonin extract, caffeine extract, rosemary oil vs.: Placebo Wirkung: several CAMs effective vs baseline or minoxidil with minimal side effects None

animal experimental study

Sleep-promoting activity of amylase-treated Ashwagandha (Withania somnifera L. Dunal) root extract via GABA receptors.

Dose: dose-dependent (specific doses not reported in abstract) vs.: Placebo Wirkung: None None

Key Statistics

Studien

Teilnehmer

↑

Positive

Bewertung

Referenced Papers

A Canadian Consensus on Androgenetic Alopecia: Approach and Management. Other

Journal of cutaneous … 2025 2 Zitierungen

Do Non-Prescription Products Help in Managing Androgenic Alopecia? Review

Skin appendage disorders 2025 1 Zitierungen

Personalized Compounded Hair Loss Treatments: A Compatibility Assessment of the TrichoConcept™ Vehicle Line. Other

International journal of … 2025

[Nutrition in improving sleep quality and fighting insomnia]. Review

Nutricion hospitalaria 2025

Complementary and alternative supplements: a review of dermatologic effectiveness for androgenetic alopecia. Review

Proceedings (Baylor University. … 2024 14 Zitierungen

Sleep-promoting activity of amylase-treated Ashwagandha (Withania somnifera L. Dunal) root extract via GABA receptors. Other

Journal of food … 2023 17 Zitierungen

Natural products for male androgenetic alopecia. Review

Dermatologic therapy 2022 41 Zitierungen

Reduction of telogen rate and increase of hair density in androgenetic alopecia by a cosmetic product: Results of a randomized, … RCT

Journal of cosmetic … 2022 11 Zitierungen

Evidence for supplemental treatments in androgenetic alopecia. Other

Journal of drugs … 2014 26 Zitierungen

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Übliche Dosierungen

topical:: 0.2% caffeine shampoo or serum

Obergrenze: Topical only

In der Forschung untersuchte Dosierungen

Dosierung	Dauer	Wirkung	N
Various non-prescription agents: procyanidin, cetirizine, caffeine, Oryza sativa bran, pumpkin seed	--	Positive	--
None	--	Positive	--
F1: biotin 0.5%, caffeine 2.0%, niacinamide 2.0%; F2: finasteride 0.1%, minoxidil 1.0%, tretinoin 0.	26 weeks	Positive	--
tryptophan, carbohydrates, omega-3, vitamins (B6, B12, folate, niacin, D, C, beta-carotene), mineral	--	Positive	--
various CAMs: pumpkin seed oil, saw palmetto, melatonin extract, caffeine extract, rosemary oil	--	Positive	--
dose-dependent (specific doses not reported in abstract)	--	Positive	--
None	--	Positive	--
foam applied twice daily containing nicotinic acid hexyl ester, polyphenols, zinc, glycine, and caff	26 weeks	Positive	62

Beste Einnahmezeit: Apply shampoo or serum to scalp, leave on for 2 minutes before rinsing

Safety & Side Effects

Gemeldete Nebenwirkungen

⚠ Scalp irritation or dryness
⚠ Minimal systemic absorption (low risk of systemic effects)
⚠ Contact sensitization (rare)

Bekannte Wechselwirkungen

● Minoxidil (may be used in combination; no significant interaction)
● Other topical scalp products (apply at separate times)

Tolerierbare Höchstaufnahmemenge: Topical only

Konsultieren Sie immer Ihren Arzt, bevor Sie ein Nahrungsergänzungsmittel einnehmen.Konsultieren Sie immer Ihren Arzt, bevor Sie ein Nahrungsergänzungsmittel einnehmen.

Frequently Asked Questions

Does Koffein (topisch) help with Androgenetische Alopezie?

Based on 9 studies with 62 participants, there is moderate evidence from clinical studies that Koffein (topisch) may support Androgenetische Alopezie management. Our evidence grade is B (Good Evidence).

How much Koffein (topisch) should I take for Androgenetische Alopezie?

Studies have used various dosages. A commonly studied range is 0.2% caffeine shampoo or serum. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Koffein (topisch)?

Reported side effects may include Scalp irritation or dryness, Minimal systemic absorption (low risk of systemic effects), Contact sensitization (rare). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Koffein (topisch) and Androgenetische Alopezie?

We rate the evidence as Grade B (Good Evidence). This rating is based on 9 peer-reviewed studies with 62 total participants. The overall direction of effect is positive.

Related Evidence

Andere Inhaltsstoffe für Androgenetische Alopezie

Minoxidil A Finasterid A PRP-Therapie A Dutasterid A Omega-3-Fettsäuren A Microneedling A

Kurzfazit

Basierend auf 9 Studien (1 RCT) mit 62 Teilnehmern insgesamt. 8/9 Studien zeigen positive Effekte.

Evidence Strength72%

High confidence

Studienübersicht

RCT (1)Meta (0)Other (8)

Alternativen vergleichen

Sehen Sie, wie andere Inhaltsstoffe bei dieser Beschwerde abschneiden.

Alle Inhaltsstoffe ansehen für Androgenetische Alopezie

Mehr erfahren

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