Dutasterid für Androgenetische Alopezie
A Evidenz Mehrere große klinische Studien zeigen übereinstimmend signifikante Vorteile.Basierend auf 43 Studien (7 meta-analyses, 1 RCT) mit 12,060 Teilnehmern insgesamt. 34/43 Studien zeigen positive Effekte.
Fazit
Dutasteride has strong scientific support for androgenetic alopecia and research suggests it may be more effective than finasteride, though it should be used under medical supervision due to potential side effects.
- 34 out of 43 studies show positive effects across 12,060 participants
- Multiple meta-analyses consistently support dutasteride's effectiveness for pattern hair loss
- Blocks both type I and type II 5-alpha reductase enzymes, potentially offering broader DHT reduction than finasteride
- Available in both oral and topical formulations, with topical forms being actively researched
Key Study Findings
Population: women with androgenetic alopecia (female pattern hair loss)
Population: Men with androgenetic alopecia
Population: Adult males with androgenetic alopecia
Population: 10 males + 10 postmenopausal females with resistant AGA
Key Statistics
99
Studien
19921
Teilnehmer
Positive
Bewertung
Referenced Papers
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Übliche Dosierungen
- hairloss:
- 0.5 mg/day (off-label)
Obergrenze: 0.5 mg/day
In der Forschung untersuchte Dosierungen
| Dosierung | Dauer | Wirkung | N |
|---|---|---|---|
| None | -- | Neutral | -- |
| 0.2 mg dutasteride daily | 24 weeks | Positive | 139 |
| 3 sessions of dutasteride microinfusion (monthly) | 12 weeks | Positive | 8 |
| 4 monthly sessions of SPi + iontophoresis | 8 weeks | Positive | 20 |
| Dutasteride (oral, various doses) | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
Beste Einnahmezeit: Once daily at the same time, with or without food; prescription required
Safety & Side Effects
Gemeldete Nebenwirkungen
- ⚠ Decreased libido (more common than finasteride)
- ⚠ Erectile dysfunction
- ⚠ Ejaculation disorders
- ⚠ Gynecomastia (breast tissue growth)
- ⚠ Very long half-life (~5 weeks) means slow side effect resolution
Bekannte Wechselwirkungen
- ● CYP3A4 inhibitors (ketoconazole, ritonavir) may increase dutasteride levels
- ● May affect PSA levels (reduces by ~50%)
- ● Contraindicated in pregnancy (Category X teratogen)
Tolerierbare Höchstaufnahmemenge: 0.5 mg/day
Konsultieren Sie immer Ihren Arzt, bevor Sie ein Nahrungsergänzungsmittel einnehmen.Konsultieren Sie immer Ihren Arzt, bevor Sie ein Nahrungsergänzungsmittel einnehmen.
Frequently Asked Questions
Does Dutasterid help with Androgenetische Alopezie?
How much Dutasterid should I take for Androgenetische Alopezie?
Are there side effects of Dutasterid?
How strong is the evidence for Dutasterid and Androgenetische Alopezie?
Related Evidence
Andere Inhaltsstoffe für Androgenetische Alopezie
References
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