Saw Palmetto لـ الثعلبة الأندروجينية
Aبناءً على 21 دراسة (2 meta-analyses, 4 RCTs) بمشاركة 2,123 مشاركًا إجمالاً. 20/21 دراسة تُظهر تأثيرات إيجابية.
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A
الخلاصة
Saw palmetto is well-supported by clinical research as a natural supplement that may help slow hair loss and support regrowth in androgenetic alopecia by naturally inhibiting DHT production.
- 95% of studies (20/21) show positive effects, including 4 RCTs and 2 meta-analyses
- Works as a natural 5-alpha reductase inhibitor, reducing DHT levels
- Both oral supplementation and topical application have demonstrated benefits
- Generally well-tolerated, though less potent than prescription finasteride
Key Study Findings
Review
The Over-The-Counter Finasteride Alternative: A Critical Review of Saw Palmetto's Efficacy, Safety, and Regulatory Concerns.
Dose: None
مقابل: None
Outcome: None
التأثير: None
None
المجتمع المدروس: None
RCT
n=80
24 weeks
Double-blind
Oral Supplementation with l-Cystine, Serenoa repens, Cucurbita pepo, and Pygeum africanum in Chronic Telogen Effluvium …
Dose: 1 capsule daily (l-Cystine, Serenoa repens, Cucurbita pepo, Pygeum africanum, vitamins, micronutrien
مقابل: Placebo
التأثير: MD=+12.3 hairs/cm2 at 6 months
p<0.05
narrative review
Addressing the Root Causes of Female Hair Loss and Non-Pharmaceutical Interventions.
Dose: None
مقابل: Placebo
التأثير: None
None
narrative review
Herbal Remedies for Hair Loss: A Review of Efficacy and Safety.
Dose: varies by remedy and study
مقابل: Placebo
التأثير: None
None
systematic review
n=1658
Double-blind
Effects of dietary supplements on androgenetic alopecia: a systematic review and network meta-analysis.
Dose: various dietary supplements (Nutrafol, apple extract, tocotrienols, pumpkin seed oil, Cistanche/Lami
مقابل: Placebo
التأثير: None
None
review
Single-blind
Do Non-Prescription Products Help in Managing Androgenic Alopecia?
Dose: Various non-prescription agents: procyanidin, cetirizine, caffeine, Oryza sativa bran, pumpkin seed
مقابل: Placebo
التأثير: Considerable improvements in one or more parameters across 13 included studies
None
Key Statistics
22
الدراسات
2123
المشاركون
↑
Positive
A
التقييم
Referenced Papers
International journal of …
2026
1 اقتباسات
Skin appendage disorders
2025
7 اقتباسات
Skin appendage disorders
2025
3 اقتباسات
Frontiers in bioinformatics
2025
2 اقتباسات
International journal of …
2025
1 اقتباسات
Skin appendage disorders
2025
1 اقتباسات
Effects of dietary supplements on androgenetic alopecia: a systematic review and network meta-analysis.
Systematic Review
Frontiers in nutrition
2025
Journal of drugs …
2025
Proceedings (Baylor University. …
2024
14 اقتباسات
Expert opinion on …
2024
8 اقتباسات
Clinical, cosmetic and …
2024
7 اقتباسات
Cureus
2023
9 اقتباسات
Real-World, Open-Label Study of the Efficacy and Safety of a Novel Serum in Androgenetic Alopecia.
Other
Journal of drugs …
2023
8 اقتباسات
Clinical, cosmetic and …
2023
8 اقتباسات
Dermatologic therapy
2022
41 اقتباسات
Expert opinion on …
2020
147 اقتباسات
Archives of dermatological …
2020
51 اقتباسات
Skin appendage disorders
2020
24 اقتباسات
Journal of cosmetic …
2019
100 اقتباسات
International journal of …
2012
69 اقتباسات
Evidence-based complementary and …
2011
27 اقتباسات
The Australasian journal …
2002
20 اقتباسات
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
الجرعات الشائعة
- general:
- 320 mg/day
- hairloss:
- 320 mg/day standardized extract
الحد الأعلى: Not established
الجرعات المدروسة في الأبحاث
| الجرعة | المدة | التأثير | ن |
|---|---|---|---|
| None | -- | Neutral | -- |
| 1 capsule daily (l-Cystine, Serenoa repens, Cucurbita pepo, Pygeum africanum, vitamins, micronutrien | 24 weeks | Positive | 80 |
| None | -- | Positive | -- |
| varies by remedy and study | -- | Positive | -- |
| various dietary supplements (Nutrafol, apple extract, tocotrienols, pumpkin seed oil, Cistanche/Lami | -- | Positive | 1658 |
| Various non-prescription agents: procyanidin, cetirizine, caffeine, Oryza sativa bran, pumpkin seed | -- | Positive | -- |
| None | -- | Positive | -- |
| USPlus DERM (lipidosterolic extract of Serenoa repens) at 0.4 and 10 μg/mL in hair follicle organ cu | -- | Positive | -- |
أفضل وقت للتناول: With meals to reduce gastrointestinal side effects
Safety & Side Effects
الآثار الجانبية المُبلّغ عنها
- ⚠ Mild gastrointestinal upset (nausea, diarrhea)
- ⚠ Headache
- ⚠ Dizziness
- ⚠ Rare: decreased libido
التفاعلات المعروفة
- ● Anticoagulants and antiplatelet drugs (may increase bleeding risk)
- ● Oral contraceptives and hormone replacement therapy (anti-androgenic effects)
- ● Finasteride and dutasteride (additive 5-alpha-reductase inhibition)
الحد الأقصى المسموح به: Not established
استشر مقدم الرعاية الصحية دائماً قبل البدء بأي مكمل غذائي.
Frequently Asked Questions
Does Saw Palmetto help with الثعلبة الأندروجينية?
Based on 22 studies with 2,123 participants, there is strong evidence from multiple clinical trials that Saw Palmetto may support الثعلبة الأندروجينية management. Our evidence grade is A (Strong Evidence).
How much Saw Palmetto should I take for الثعلبة الأندروجينية?
Studies have used various dosages. A commonly studied range is 320 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Saw Palmetto?
Reported side effects may include Mild gastrointestinal upset (nausea, diarrhea), Headache, Dizziness, Rare: decreased libido. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Saw Palmetto and الثعلبة الأندروجينية?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 22 peer-reviewed studies with 2,123 total participants. The overall direction of effect is positive.
Related Evidence
مكونات أخرى لـ الثعلبة الأندروجينية
Saw Palmetto لحالات أخرى
إخلاء مسؤولية FDA: لم تُقيَّم هذه البيانات من قبل إدارة الغذاء والدواء (FDA). لا تهدف المنتجات والمعلومات الواردة في هذا الموقع إلى تشخيص أو علاج أو شفاء أو الوقاية من أي مرض. تستند تقييمات الأدلة المعروضة إلى تحليلنا للأبحاث المحكّمة المنشورة ولا تُشكّل نصيحة طبية. استشر مقدم الرعاية الصحية دائماً قبل البدء بأي نظام مكملات.