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PRP 疗法 用于 雄激素性脱发

A

基于57项研究(13项荟萃分析、6项RCT),共6,423名参与者。51/57项研究显示积极效果。

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结论

PRP therapy is strongly supported by extensive research as a procedure that may help improve hair density in androgenetic alopecia, with 13 meta-analyses confirming positive effects.

  • 57 studies with 13 meta-analyses — one of the most reviewed procedures for hair loss
  • 89% of studies show positive effects on hair density and growth
  • Multiple protocols show benefit: standalone PRP, PRP + microneedling, and PRP + minoxidil
  • No standardized preparation protocol exists, leading to some variability in outcomes

Key Study Findings

Randomized Controlled Trial n=27 12 weeks Single-blind
Platelet-Rich Plasma Treatment for Endocrine-Induced Alopecia and Persistent Chemotherapy-Induced Alopecia in Breast Cancer Survivors: A …
Dose: Monthly for 3 months vs: Untreated side of scalp (split-scalp) Outcome: Global assessment scale change at week 12 效果: +1.2 GAS; +21 hairs/cm2 treated vs +16 untreated p < 0.001 (GAS); p > 0.05 (bet

研究人群: Breast cancer survivors with EIA or pCIA

Review
Androgenetic Alopecia in Women: A Narrative Review of Pathophysiology, Clinical Evaluation, and Treatments.
Dose: None vs: None Outcome: None 效果: None None

研究人群: women with androgenetic alopecia (female pattern hair loss)

systematic review
Local Injection versus Topical Microneedling of Platelet-Rich Plasma for Androgenetic Alopecia: A Systematic Review.
Dose: Autologous platelet-rich plasma (PRP) via syringe injection or topical application with microneedlin vs: Placebo 效果: PRP combined with microneedling appeared superior to direct syringe injection; based on 3 included a None
RCT n=40 12 weeks Open-label
Phase I Clinical Trial: Evaluating the Efficacy, Safety, and Patient Satisfaction of Platelet-Rich Plasma (PRP) …
Dose: None vs: Placebo 效果: PRP: hair count +62.4%, thickness +58.6%; Microneedling: hair count +88.4%, thickness +51.3% p<0.05 (within groups); p>0.05

Key Statistics

144

研究数量

8892

受试者

Positive

A

等级

Referenced Papers

Annals of dermatology 2025
International journal of … 2024 39 次引用
Journal of cosmetic … 2024 12 次引用
Journal of cosmetic … 2024 11 次引用
Facial plastic surgery … 2024 8 次引用
Revue medicale suisse 2024 2 次引用
Clinical, cosmetic and … 2023 58 次引用
American journal of … 2023 41 次引用
International journal of … 2023 5 次引用
Clinics in plastic … 2023 1 次引用
Drug design, development … 2022 70 次引用
Faculty reviews 2022 44 次引用
Dermatology and therapy 2022 43 次引用
Journal of cosmetic … 2022 35 次引用
The journal of … 2022 22 次引用
Dermatologic surgery : … 2022 15 次引用
Skinmed 2022 3 次引用
American family physician 2022 2 次引用
Facial plastic surgery … 2022
Journal of cosmetic … 2021 23 次引用
Indian dermatology online … 2021 17 次引用
The Senior care … 2021 2 次引用
Expert opinion on … 2020 147 次引用
Facial plastic surgery … 2020 36 次引用
Indian dermatology online … 2020 33 次引用
Dermatologic surgery : … 2020 32 次引用
Journal of drugs … 2020 11 次引用
Dermatologic surgery : … 2019 68 次引用
Aesthetic plastic surgery 2019 45 次引用
Journal of cosmetic … 2019 30 次引用
Dermatologic therapy 2019 14 次引用
Indian journal of … 2019 10 次引用
Dermatologic clinics 2019 7 次引用
International journal of … 2018 129 次引用
Journal of the … 2018 114 次引用
Facial plastic surgery … 2018 43 次引用
Facial plastic surgery … 2018 42 次引用
Journal of stomatology, … 2017 30 次引用
Stem cell investigation 2017 27 次引用
International journal of … 2015 79 次引用
Journal of cutaneous … 2014 168 次引用
Dermatologic surgery : … 2014 140 次引用
Expert opinion on … 2014 57 次引用

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

常用剂量

hairloss:
3-4 sessions, 4-6 weeks apart

上限: Not applicable

研究中使用的剂量

剂量 持续时间 效果 N
Monthly for 3 months 12 weeks Neutral 27
None -- Neutral --
Autologous platelet-rich plasma (PRP) via syringe injection or topical application with microneedlin -- Positive --
None -- Positive 11
None -- Positive --
None 12 weeks Positive 40
None -- Positive --
None -- Positive --

最佳服用时间: In-clinic procedure; avoid washing hair for 24 hours after treatment

Safety & Side Effects

已报告的副作用

  • Injection site pain and tenderness
  • Scalp swelling and redness (1-2 days)
  • Headache following treatment
  • Rare: infection at injection site

已知相互作用

  • NSAIDs and aspirin (discontinue 1 week before PRP; affect platelet function)
  • Anticoagulants (may increase bruising; consult physician)
  • Corticosteroid injections (may reduce PRP effectiveness)

可耐受最高摄入量: Not applicable

在开始服用任何补充剂之前,请务必咨询您的医疗保健提供者。

Frequently Asked Questions

Does PRP 疗法 help with 雄激素性脱发?
Based on 144 studies with 8,892 participants, there is strong evidence from multiple clinical trials that PRP 疗法 may support 雄激素性脱发 management. Our evidence grade is A (Strong Evidence).
How much PRP 疗法 should I take for 雄激素性脱发?
Studies have used various dosages. A commonly studied range is 3-4 sessions, 4-6 weeks apart. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of PRP 疗法?
Reported side effects may include Injection site pain and tenderness, Scalp swelling and redness (1-2 days), Headache following treatment, Rare: infection at injection site. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for PRP 疗法 and 雄激素性脱发?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 144 peer-reviewed studies with 8,892 total participants. The overall direction of effect is positive.

Related Evidence

FDA 免责声明: 这些声明未经美国食品药品监督管理局(FDA)评估。本网站上的产品和信息无意用于诊断、治疗、治愈或预防任何疾病。所展示的证据等级基于我们对已发表的同行评审研究的分析,不构成医疗建议。在开始任何补充剂方案之前,请务必咨询您的医疗保健提供者。