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Кофеин (топический) для Андрогенетическая алопеция

B

На основе 9 исследований (1 RCT) с участием 62 участников. 8/9 исследований показывают положительные эффекты.

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B

Итог

Topical caffeine shows promising early evidence for supporting hair growth in androgenetic alopecia, but the research base is still small and more large-scale human trials are needed.

  • 8 out of 9 studies report positive effects on hair growth
  • Caffeine may work by counteracting DHT's negative effects on hair follicles
  • One RCT showed improved hair density with a caffeine-containing topical product
  • The total participant pool is very small (62 people), limiting the strength of conclusions

Key Study Findings

review Single-blind
Do Non-Prescription Products Help in Managing Androgenic Alopecia?
Dose: Various non-prescription agents: procyanidin, cetirizine, caffeine, Oryza sativa bran, pumpkin seed или: Placebo Эффект: Considerable improvements in one or more parameters across 13 included studies None
Review
A Canadian Consensus on Androgenetic Alopecia: Approach and Management.
Dose: None или: Placebo Эффект: None None
laboratory/in vitro 26 weeks
Personalized Compounded Hair Loss Treatments: A Compatibility Assessment of the TrichoConcept™ Vehicle Line.
Dose: F1: biotin 0.5%, caffeine 2.0%, niacinamide 2.0%; F2: finasteride 0.1%, minoxidil 1.0%, tretinoin 0. или: Placebo Эффект: F1 and F3 stable for 180 days; F2 stable for 14 days; F4 and F5 stable for 150 days; F6/F7 stable fo None
review
[Nutrition in improving sleep quality and fighting insomnia].
Dose: tryptophan, carbohydrates, omega-3, vitamins (B6, B12, folate, niacin, D, C, beta-carotene), mineral или: Placebo Эффект: None None
review
Complementary and alternative supplements: a review of dermatologic effectiveness for androgenetic alopecia.
Dose: various CAMs: pumpkin seed oil, saw palmetto, melatonin extract, caffeine extract, rosemary oil или: Placebo Эффект: several CAMs effective vs baseline or minoxidil with minimal side effects None
animal experimental study
Sleep-promoting activity of amylase-treated Ashwagandha (Withania somnifera L. Dunal) root extract via GABA receptors.
Dose: dose-dependent (specific doses not reported in abstract) или: Placebo Эффект: None None

Key Statistics

9

Исследования

62

Участники

Positive

B

Оценка

Referenced Papers

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Часто используемые дозировки

topical:
0.2% caffeine shampoo or serum

Верхний предел: Topical only

Дозировки, изученные в исследованиях

Дозировка Длительность Эффект N
Various non-prescription agents: procyanidin, cetirizine, caffeine, Oryza sativa bran, pumpkin seed -- Positive --
None -- Positive --
F1: biotin 0.5%, caffeine 2.0%, niacinamide 2.0%; F2: finasteride 0.1%, minoxidil 1.0%, tretinoin 0. 26 weeks Positive --
tryptophan, carbohydrates, omega-3, vitamins (B6, B12, folate, niacin, D, C, beta-carotene), mineral -- Positive --
various CAMs: pumpkin seed oil, saw palmetto, melatonin extract, caffeine extract, rosemary oil -- Positive --
dose-dependent (specific doses not reported in abstract) -- Positive --
None -- Positive --
foam applied twice daily containing nicotinic acid hexyl ester, polyphenols, zinc, glycine, and caff 26 weeks Positive 62

Лучшее время приёма: Apply shampoo or serum to scalp, leave on for 2 minutes before rinsing

Safety & Side Effects

Зарегистрированные побочные эффекты

  • Scalp irritation or dryness
  • Minimal systemic absorption (low risk of systemic effects)
  • Contact sensitization (rare)

Известные взаимодействия

  • Minoxidil (may be used in combination; no significant interaction)
  • Other topical scalp products (apply at separate times)

Допустимый верхний уровень потребления: Topical only

Всегда консультируйтесь с врачом перед началом приёма любых добавок.Всегда консультируйтесь с лечащим врачом перед началом приёма любой добавки.

Frequently Asked Questions

Does Кофеин (топический) help with Андрогенетическая алопеция?
Based on 9 studies with 62 participants, there is moderate evidence from clinical studies that Кофеин (топический) may support Андрогенетическая алопеция management. Our evidence grade is B (Good Evidence).
How much Кофеин (топический) should I take for Андрогенетическая алопеция?
Studies have used various dosages. A commonly studied range is 0.2% caffeine shampoo or serum. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Кофеин (топический)?
Reported side effects may include Scalp irritation or dryness, Minimal systemic absorption (low risk of systemic effects), Contact sensitization (rare). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Кофеин (топический) and Андрогенетическая алопеция?
We rate the evidence as Grade B (Good Evidence). This rating is based on 9 peer-reviewed studies with 62 total participants. The overall direction of effect is positive.

Related Evidence

Отказ от ответственности FDA: Данные утверждения не были оценены Управлением по санитарному надзору за качеством пищевых продуктов и медикаментов (FDA). Продукты и информация на этом сайте не предназначены для диагностики, лечения, излечения или профилактики каких-либо заболеваний. Представленные оценки доказательности основаны на нашем анализе опубликованных рецензируемых исследований и не являются медицинской консультацией. Всегда консультируйтесь с лечащим врачом перед началом приёма любых добавок.