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HairCited

Androgens and hair loss.

Adel Alsantali, Jerry Shapiro
Review Current opinion in endocrinology, diabetes, and obesity 2009 54 件の引用
PubMed DOI
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Study Design

研究タイプ
Review
対象集団
None
介入
Androgens and hair loss. None
比較対照
None
主要アウトカム
Androgens and hair loss.
効果の方向
Positive
バイアスリスク
Unclear

Abstract

PURPOSE OF REVIEW: Androgenetic alopecia (AGA) or male pattern hair loss is a very common condition that has a significant psychosocial impact for patients. Many advances in the pathogenesis and treatment of AGA have been discovered recently. We discuss the pathogenesis and treatment of AGA. RECENT FINDINGS: Wide genome analysis showed an association of AGA and chromosome 20pll in addition to androgen-receptor gene. Also, a locus on chromosome 3q26 was found to have a linkage with AGA. Dutasteride has been shown to be more effective than finasteride in the treatment of AGA but is not yet a recommended therapy. In an in-vitro study, a new topical liposomal finasteride formulation showed more than five-fold higher deposition of drug in skin than the corresponding plain drug solution. SUMMARY: These recent developments in the field of AGA hold some promise and may play a role in the future management.

要約

The pathogenesis and treatment of AGA is discussed and a new topical liposomal finasteride formulation showed more than five-fold higher deposition of drug in skin than the corresponding plain drug solution.

Used In Evidence Reviews

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