ビタミンB12 ：休止期脱毛症

Q: Does ビタミンB12 help with 休止期脱毛症?

Based on 13 studies with 8,121 participants, there is insufficient evidence at this time that ビタミンB12 may support 休止期脱毛症 management. Our evidence grade is F (Evidence Against).

Q: How much ビタミンB12 should I take for 休止期脱毛症?

Studies have used various dosages. A commonly studied range is 2.4 mcg/day. Always consult your healthcare provider before starting any supplement regimen.

Q: Are there side effects of ビタミンB12?

Reported side effects may include Generally well tolerated even at high doses, Rare allergic reactions (itching, swelling), Mild diarrhea or nausea at very high doses. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

Q: How strong is the evidence for ビタミンB12 and 休止期脱毛症?

We rate the evidence as Grade F (Evidence Against). This rating is based on 13 peer-reviewed studies with 8,121 total participants. The overall direction of effect is mixed.

F 効果研究によると、この用途への効果は期待しにくい可能性があります。

合計8,121名の参加者を対象とした13件の研究に基づく。研究間で結果にばらつきが見られる。

𝕏 LinkedIn

<\/script>\n

`; }, get iframeSnippet() { const domain = 'haircited.com'; const params = 'ingredient\u003Dvitamin\u002Db12\u0026condition\u003Dtelogen\u002Deffluvium'; return ``; }, get activeSnippet() { return this.method === 'script' ? this.scriptSnippet : this.iframeSnippet; }, copySnippet() { navigator.clipboard.writeText(this.activeSnippet).then(() => { this.copied = true; setTimeout(() => { this.copied = false; }, 2000); }); } }" @keydown.escape.window="open = false" @click.outside="open = false">

Embed This Widget

Style

Widget powered by . Free, no account required.

結論

Research does not clearly support vitamin B12 supplementation for telogen effluvium — while low B12 is sometimes found in hair loss patients, there is no strong evidence that supplementation helps recovery.

Mixed results across 13 observational studies
Some post-COVID hair loss studies measured B12 levels without finding consistent patterns
No RCTs testing B12 supplementation for telogen effluvium
Only worth supplementing if a blood test confirms a B12 deficiency

Key Study Findings

retrospective observational n=113

Telogen Effluvium Following Coronavirus Disease-2019 Infection: A Retrospective Study of 113 Cases.

Dose: None vs: Placebo 効果: None None

Retrospective cohort n=2851

Retrospective Review of 2851 Female Patients With Telogen Effluvium: A Single-Center Experience.

Dose: None vs: Placebo 効果: Ferritin low in 46.5% of patients; iron deficiency in 29.5% p<0.05

Cross-Sectional Study n=108

Evaluation of the relationship of digital phototrichogram findings of patients with diffuse hair loss with …

Dose: None vs: Placebo 効果: None 0.05

case-control study n=180

A comprehensive investigation of biochemical status in patients with telogen effluvium: Analysis of Hb, ferritin, …

Dose: not applicable vs: Placebo 効果: None None

Case-control n=973

Micronutrient Deficiencies and Digital Computerized Phototrichogram Analysis in Telogen Effluvium: a Retrospective Correlation Study in …

Dose: None vs: Placebo 効果: r=0.417 (HGB and AHR in females) p=0.008

retrospective cross-sectional study n=467

Nonscarring scalp alopecia: Which laboratory analysis should we perform on whom?

Dose: not applicable vs: Placebo 効果: None 0.001

Key Statistics

研究数

8121

参加者数

↔

Mixed

グレード

Referenced Papers

Retrospective Review of 2851 Female Patients With Telogen Effluvium: A Single-Center Experience. Other

Journal of cosmetic … 2025 4 件の引用

Telogen Effluvium Following Coronavirus Disease-2019 Infection: A Retrospective Study of 113 Cases. Other

International journal of … 2025

A comprehensive investigation of biochemical status in patients with telogen effluvium: Analysis of Hb, ferritin, vitamin B12, vitamin D, thyroid … Other

Journal of cosmetic … 2024 7 件の引用

Evaluation of the relationship of digital phototrichogram findings of patients with diffuse hair loss with blood TSH, ferritin and vitamin … Other

Northern clinics of … 2024 1 件の引用

Micronutrient Deficiencies and Digital Computerized Phototrichogram Analysis in Telogen Effluvium: a Retrospective Correlation Study in a Tertiary Medical Center. Other

Dermatology practical & … 2023 4 件の引用

Telogen effluvium in daily practice: Patient characteristics, laboratory parameters, and treatment modalities of 3028 patients with telogen effluvium. Other

Journal of cosmetic … 2022 22 件の引用

Nonscarring scalp alopecia: Which laboratory analysis should we perform on whom? Other

Turkish journal of … 2022 8 件の引用

NonScarring Diffuse Hair Loss in Women: a Clinico-Etiological Study from tertiary care center in North-West India. Observational

Journal of cosmetic … 2019 25 件の引用

Vitamin and Mineral Deficiencies in Patients With Telogen Effluvium: A Retrospective Cross-Sectional Study. Other

Journal of drugs … 2016 56 件の引用

Clinicoepidemiological Observational Study of Acquired Alopecias in Females Correlating with Anemia and Thyroid Function. Other

Dermatology research and … 2016 26 件の引用

Trichotillomania: Bizzare Patern of Hair Loss at 11-Year-old Girl. Case Report

Acta dermatovenerologica Croatica … 2016 6 件の引用

The role of psychological factors and serum zinc, folate and vitamin B12 levels in the aetiology of trichodynia: a case-control … Other

Clinical and experimental … 2009 34 件の引用

Management of hair loss in women. Review

Dermatologic clinics 1993 38 件の引用

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

一般的な使用量

general:: 2.4 mcg/day
deficiency:: 1,000-2,000 mcg/day

上限量： No established UL

研究で検討された用量

用量	期間	効果	N
None	--	Neutral	113
None	--	Neutral	2851
None	--	Mixed	108
not applicable	--	Mixed	180
None	--	Positive	973
not applicable	--	Mixed	467
standard replacement doses	--	Neutral	3028
None	--	Neutral	100

推奨摂取タイミング： With meals; sublingual form can be taken any time

Safety & Side Effects

報告されている副作用

⚠ Generally well tolerated even at high doses
⚠ Rare allergic reactions (itching, swelling)
⚠ Mild diarrhea or nausea at very high doses

既知の相互作用

● Metformin (reduces B12 absorption by 10-30%)
● Proton pump inhibitors and H2 blockers (reduce B12 absorption)
● Colchicine (may reduce B12 absorption)

耐容上限摂取量： No established UL

サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。

Frequently Asked Questions

Does ビタミンB12 help with 休止期脱毛症?

Based on 13 studies with 8,121 participants, there is insufficient evidence at this time that ビタミンB12 may support 休止期脱毛症 management. Our evidence grade is F (Evidence Against).

How much ビタミンB12 should I take for 休止期脱毛症?

Studies have used various dosages. A commonly studied range is 2.4 mcg/day. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of ビタミンB12?

Reported side effects may include Generally well tolerated even at high doses, Rare allergic reactions (itching, swelling), Mild diarrhea or nausea at very high doses. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for ビタミンB12 and 休止期脱毛症?

We rate the evidence as Grade F (Evidence Against). This rating is based on 13 peer-reviewed studies with 8,121 total participants. The overall direction of effect is mixed.

に関する他の成分：休止期脱毛症

ミノキシジル A ブラックシードオイル A ビビスカル A 鉄 B ケラチン B オメガ3脂肪酸 B

ビタミンB12 他の症状・状態について

栄養不足による脱毛症 F

総合評価

合計8,121名の参加者を対象とした13件の研究に基づく。研究間で結果にばらつきが見られる。

Evidence Strength10%

Low confidence

研究の内訳

RCT (0)Meta (0)Other (13)

代替成分との比較

この症状に対する他の成分との比較をご覧ください。

に関するすべての成分を見る：休止期脱毛症

詳しく見る

References

[1] Ömer Karakoyun et al.. J Cosmet Dermatol. 2025. Retrospective Review of 2851 Female Patients With Telogen Effluvium: A Single-Center Experience. doi:10.1111/jocd.70037 PubMed
[2] Namrata Chhabra et al.. Int J Trichology. 2025. Telogen Effluvium Following Coronavirus Disease-2019 Infection: A Retrospective Study of 113 Cases. doi:10.4103/ijt.ijt_38_22 PubMed
[3] Irem Nur Durusu Turkoglu et al.. J Cosmet Dermatol. 2024. A comprehensive investigation of biochemical status in patients with telogen effluvium: Analysis of Hb, ferritin, vitamin B12, vitamin D, thyroid … doi:10.1111/jocd.16512 PubMed
[4] Leyla Bilik et al.. North Clin Istanb. 2024. Evaluation of the relationship of digital phototrichogram findings of patients with diffuse hair loss with blood TSH, ferritin and vitamin … doi:10.14744/nci.2023.33269 PubMed
[5] Hakan Arslan et al.. Dermatol Pract Concept. 2023. Micronutrient Deficiencies and Digital Computerized Phototrichogram Analysis in Telogen Effluvium: a Retrospective Correlation Study in a Tertiary Medical Center. doi:10.5826/dpc.1303a202 PubMed
[6] Ahu Yorulmaz et al.. J Cosmet Dermatol. 2022. Telogen effluvium in daily practice: Patient characteristics, laboratory parameters, and treatment modalities of 3028 patients with telogen effluvium. doi:10.1111/jocd.14413 PubMed
[7] Ümran Öner et al.. Turk J Med Sci. 2022. Nonscarring scalp alopecia: Which laboratory analysis should we perform on whom? doi:10.3906/sag-2106-28 PubMed
[8] Kavita Poonia et al.. J Cosmet Dermatol. 2019. NonScarring Diffuse Hair Loss in Women: a Clinico-Etiological Study from tertiary care center in North-West India. doi:10.1111/jocd.12559 PubMed
[9] Evelyn J Cheung et al.. J Drugs Dermatol. 2016. Vitamin and Mineral Deficiencies in Patients With Telogen Effluvium: A Retrospective Cross-Sectional Study. PubMed
[10] Kirti Deo et al.. Dermatol Res Pract. 2016. Clinicoepidemiological Observational Study of Acquired Alopecias in Females Correlating with Anemia and Thyroid Function. doi:10.1155/2016/6279108 PubMed
[11] Jana Zímová et al.. Acta Dermatovenerol Croat. 2016. Trichotillomania: Bizzare Patern of Hair Loss at 11-Year-old Girl. PubMed
[12] C Durusoy et al.. Clin Exp Dermatol. 2009. The role of psychological factors and serum zinc, folate and vitamin B12 levels in the aetiology of trichodynia: a case-control … doi:10.1111/j.1365-2230.2008.03165.x PubMed
[13] D H Rushton. Dermatol Clin. 1993. Management of hair loss in women. PubMed

FDAに関する免責事項: これらの記述は米国食品医薬品局（FDA）による評価を受けていません。本ウェブサイトの製品および情報は、疾病の診断、治療、治癒、または予防を目的としたものではありません。表示されているエビデンスグレードは、公開された査読済み研究の分析に基づいており、医療上の助言を構成するものではありません。サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。

ビタミンB12 ： 休止期脱毛症