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Vitamin B12 für Telogen Effluvium

F Wirkung Die Forschung zeigt, dass dies für diese Anwendung wahrscheinlich nicht wirksam ist.

Basierend auf 13 Studien mit 8,121 Teilnehmern insgesamt. Die Ergebnisse sind uneinheitlich zwischen den Studien.

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F

Fazit

Research does not clearly support vitamin B12 supplementation for telogen effluvium — while low B12 is sometimes found in hair loss patients, there is no strong evidence that supplementation helps recovery.

  • Mixed results across 13 observational studies
  • Some post-COVID hair loss studies measured B12 levels without finding consistent patterns
  • No RCTs testing B12 supplementation for telogen effluvium
  • Only worth supplementing if a blood test confirms a B12 deficiency

Key Study Findings

retrospective observational n=113
Telogen Effluvium Following Coronavirus Disease-2019 Infection: A Retrospective Study of 113 Cases.
Dose: None vs.: Placebo Wirkung: None None
Retrospective cohort n=2851
Retrospective Review of 2851 Female Patients With Telogen Effluvium: A Single-Center Experience.
Dose: None vs.: Placebo Wirkung: Ferritin low in 46.5% of patients; iron deficiency in 29.5% p<0.05
retrospective cross-sectional study n=467
Nonscarring scalp alopecia: Which laboratory analysis should we perform on whom?
Dose: not applicable vs.: Placebo Wirkung: None 0.001

Key Statistics

13

Studien

8121

Teilnehmer

Mixed

F

Bewertung

Referenced Papers

Acta dermatovenerologica Croatica … 2016 6 Zitierungen
Dermatologic clinics 1993 38 Zitierungen

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Übliche Dosierungen

general:
2.4 mcg/day
deficiency:
1,000-2,000 mcg/day

Obergrenze: No established UL

In der Forschung untersuchte Dosierungen

Dosierung Dauer Wirkung N
None -- Neutral 113
None -- Neutral 2851
None -- Mixed 108
not applicable -- Mixed 180
None -- Positive 973
not applicable -- Mixed 467
standard replacement doses -- Neutral 3028
None -- Neutral 100

Beste Einnahmezeit: With meals; sublingual form can be taken any time

Safety & Side Effects

Gemeldete Nebenwirkungen

  • Generally well tolerated even at high doses
  • Rare allergic reactions (itching, swelling)
  • Mild diarrhea or nausea at very high doses

Bekannte Wechselwirkungen

  • Metformin (reduces B12 absorption by 10-30%)
  • Proton pump inhibitors and H2 blockers (reduce B12 absorption)
  • Colchicine (may reduce B12 absorption)

Tolerierbare Höchstaufnahmemenge: No established UL

Konsultieren Sie immer Ihren Arzt, bevor Sie ein Nahrungsergänzungsmittel einnehmen.Konsultieren Sie immer Ihren Arzt, bevor Sie ein Nahrungsergänzungsmittel einnehmen.

Frequently Asked Questions

Does Vitamin B12 help with Telogen Effluvium?
Based on 13 studies with 8,121 participants, there is insufficient evidence at this time that Vitamin B12 may support Telogen Effluvium management. Our evidence grade is F (Evidence Against).
How much Vitamin B12 should I take for Telogen Effluvium?
Studies have used various dosages. A commonly studied range is 2.4 mcg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Vitamin B12?
Reported side effects may include Generally well tolerated even at high doses, Rare allergic reactions (itching, swelling), Mild diarrhea or nausea at very high doses. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Vitamin B12 and Telogen Effluvium?
We rate the evidence as Grade F (Evidence Against). This rating is based on 13 peer-reviewed studies with 8,121 total participants. The overall direction of effect is mixed.

References

  1. [1] Ömer Karakoyun et al.. J Cosmet Dermatol. 2025. Retrospective Review of 2851 Female Patients With Telogen Effluvium: A Single-Center Experience. doi:10.1111/jocd.70037 PubMed
  2. [2] Namrata Chhabra et al.. Int J Trichology. 2025. Telogen Effluvium Following Coronavirus Disease-2019 Infection: A Retrospective Study of 113 Cases. doi:10.4103/ijt.ijt_38_22 PubMed
  3. [3] Irem Nur Durusu Turkoglu et al.. J Cosmet Dermatol. 2024. A comprehensive investigation of biochemical status in patients with telogen effluvium: Analysis of Hb, ferritin, vitamin B12, vitamin D, thyroid … doi:10.1111/jocd.16512 PubMed
  4. [4] Leyla Bilik et al.. North Clin Istanb. 2024. Evaluation of the relationship of digital phototrichogram findings of patients with diffuse hair loss with blood TSH, ferritin and vitamin … doi:10.14744/nci.2023.33269 PubMed
  5. [5] Hakan Arslan et al.. Dermatol Pract Concept. 2023. Micronutrient Deficiencies and Digital Computerized Phototrichogram Analysis in Telogen Effluvium: a Retrospective Correlation Study in a Tertiary Medical Center. doi:10.5826/dpc.1303a202 PubMed
  6. [6] Ahu Yorulmaz et al.. J Cosmet Dermatol. 2022. Telogen effluvium in daily practice: Patient characteristics, laboratory parameters, and treatment modalities of 3028 patients with telogen effluvium. doi:10.1111/jocd.14413 PubMed
  7. [7] Ümran Öner et al.. Turk J Med Sci. 2022. Nonscarring scalp alopecia: Which laboratory analysis should we perform on whom? doi:10.3906/sag-2106-28 PubMed
  8. [8] Kavita Poonia et al.. J Cosmet Dermatol. 2019. NonScarring Diffuse Hair Loss in Women: a Clinico-Etiological Study from tertiary care center in North-West India. doi:10.1111/jocd.12559 PubMed
  9. [9] Evelyn J Cheung et al.. J Drugs Dermatol. 2016. Vitamin and Mineral Deficiencies in Patients With Telogen Effluvium: A Retrospective Cross-Sectional Study. PubMed
  10. [10] Kirti Deo et al.. Dermatol Res Pract. 2016. Clinicoepidemiological Observational Study of Acquired Alopecias in Females Correlating with Anemia and Thyroid Function. doi:10.1155/2016/6279108 PubMed
  11. [11] Jana Zímová et al.. Acta Dermatovenerol Croat. 2016. Trichotillomania: Bizzare Patern of Hair Loss at 11-Year-old Girl. PubMed
  12. [12] C Durusoy et al.. Clin Exp Dermatol. 2009. The role of psychological factors and serum zinc, folate and vitamin B12 levels in the aetiology of trichodynia: a case-control … doi:10.1111/j.1365-2230.2008.03165.x PubMed
  13. [13] D H Rushton. Dermatol Clin. 1993. Management of hair loss in women. PubMed

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