ビタミンB12 ： 休止期脱毛症
F合計8,121名の参加者を対象とした13件の研究に基づく。研究間で結果にばらつきが見られる。
<\/script>\n`;
},
get iframeSnippet() {
const domain = 'haircited.com';
const params = 'ingredient\u003Dvitamin\u002Db12\u0026condition\u003Dtelogen\u002Deffluvium';
return ``;
},
get activeSnippet() {
return this.method === 'script' ? this.scriptSnippet : this.iframeSnippet;
},
copySnippet() {
navigator.clipboard.writeText(this.activeSnippet).then(() => {
this.copied = true;
setTimeout(() => { this.copied = false; }, 2000);
});
}
}"
@keydown.escape.window="open = false"
@click.outside="open = false">
F
結論
Research does not clearly support vitamin B12 supplementation for telogen effluvium — while low B12 is sometimes found in hair loss patients, there is no strong evidence that supplementation helps recovery.
- Mixed results across 13 observational studies
- Some post-COVID hair loss studies measured B12 levels without finding consistent patterns
- No RCTs testing B12 supplementation for telogen effluvium
- Only worth supplementing if a blood test confirms a B12 deficiency
Key Study Findings
retrospective observational
n=113
Telogen Effluvium Following Coronavirus Disease-2019 Infection: A Retrospective Study of 113 Cases.
Dose: None
vs: Placebo
効果: None
None
Retrospective cohort
n=2851
Retrospective Review of 2851 Female Patients With Telogen Effluvium: A Single-Center Experience.
Dose: None
vs: Placebo
効果: Ferritin low in 46.5% of patients; iron deficiency in 29.5%
p<0.05
Cross-Sectional Study
n=108
Evaluation of the relationship of digital phototrichogram findings of patients with diffuse hair loss with …
Dose: None
vs: Placebo
効果: None
0.05
case-control study
n=180
A comprehensive investigation of biochemical status in patients with telogen effluvium: Analysis of Hb, ferritin, …
Dose: not applicable
vs: Placebo
効果: None
None
Case-control
n=973
Micronutrient Deficiencies and Digital Computerized Phototrichogram Analysis in Telogen Effluvium: a Retrospective Correlation Study in …
Dose: None
vs: Placebo
効果: r=0.417 (HGB and AHR in females)
p=0.008
retrospective cross-sectional study
n=467
Nonscarring scalp alopecia: Which laboratory analysis should we perform on whom?
Dose: not applicable
vs: Placebo
効果: None
0.001
Key Statistics
13
研究数
8121
参加者数
↔
Mixed
F
グレード
Referenced Papers
Retrospective Review of 2851 Female Patients With Telogen Effluvium: A Single-Center Experience.
Other
Journal of cosmetic …
2025
4 件の引用
Telogen Effluvium Following Coronavirus Disease-2019 Infection: A Retrospective Study of 113 Cases.
Other
International journal of …
2025
Journal of cosmetic …
2024
7 件の引用
Northern clinics of …
2024
1 件の引用
Dermatology practical & …
2023
4 件の引用
Journal of cosmetic …
2022
22 件の引用
Turkish journal of …
2022
8 件の引用
NonScarring Diffuse Hair Loss in Women: a Clinico-Etiological Study from tertiary care center in North-West India.
Observational
Journal of cosmetic …
2019
25 件の引用
Journal of drugs …
2016
56 件の引用
Dermatology research and …
2016
26 件の引用
Acta dermatovenerologica Croatica …
2016
6 件の引用
Clinical and experimental …
2009
34 件の引用
Dermatologic clinics
1993
38 件の引用
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
一般的な使用量
- general:
- 2.4 mcg/day
- deficiency:
- 1,000-2,000 mcg/day
上限量： No established UL
研究で検討された用量
| 用量 | 期間 | 効果 | N |
|---|---|---|---|
| None | -- | Neutral | 113 |
| None | -- | Neutral | 2851 |
| None | -- | Mixed | 108 |
| not applicable | -- | Mixed | 180 |
| None | -- | Positive | 973 |
| not applicable | -- | Mixed | 467 |
| standard replacement doses | -- | Neutral | 3028 |
| None | -- | Neutral | 100 |
推奨摂取タイミング： With meals; sublingual form can be taken any time
Safety & Side Effects
報告されている副作用
- ⚠ Generally well tolerated even at high doses
- ⚠ Rare allergic reactions (itching, swelling)
- ⚠ Mild diarrhea or nausea at very high doses
既知の相互作用
- ● Metformin (reduces B12 absorption by 10-30%)
- ● Proton pump inhibitors and H2 blockers (reduce B12 absorption)
- ● Colchicine (may reduce B12 absorption)
耐容上限摂取量： No established UL
サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。
Frequently Asked Questions
Does ビタミンB12 help with 休止期脱毛症?
Based on 13 studies with 8,121 participants, there is insufficient evidence at this time that ビタミンB12 may support 休止期脱毛症 management. Our evidence grade is F (Evidence Against).
How much ビタミンB12 should I take for 休止期脱毛症?
Studies have used various dosages. A commonly studied range is 2.4 mcg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of ビタミンB12?
Reported side effects may include Generally well tolerated even at high doses, Rare allergic reactions (itching, swelling), Mild diarrhea or nausea at very high doses. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for ビタミンB12 and 休止期脱毛症?
We rate the evidence as Grade F (Evidence Against). This rating is based on 13 peer-reviewed studies with 8,121 total participants. The overall direction of effect is mixed.
Related Evidence
ビタミンB12 他の症状・状態について
FDAに関する免責事項: これらの記述は米国食品医薬品局（FDA）による評価を受けていません。本ウェブサイトの製品および情報は、疾病の診断、治療、治癒、または予防を目的としたものではありません。表示されているエビデンスグレードは、公開された査読済み研究の分析に基づいており、医療上の助言を構成するものではありません。サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。