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PRP療法 円形脱毛症

A

合計2,376名の参加者を対象とした21件の研究(メタアナリシス4件、RCT 2件を含む)に基づく。21件中18件の研究で肯定的な効果が示されている。

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A

結論

PRP therapy is well-supported by research as a procedure that may help stimulate hair regrowth in alopecia areata, with multiple meta-analyses confirming its potential benefits.

  • 86% of studies (18/21) show positive effects, backed by 4 meta-analyses
  • Multiple delivery methods studied: injection, microneedling, and laser-assisted
  • 2,376 participants across studies of varying design quality
  • Results may vary due to the unpredictable nature of autoimmune alopecia areata

Key Study Findings

Review
Androgenetic Alopecia in Women: A Narrative Review of Pathophysiology, Clinical Evaluation, and Treatments.
Dose: None vs: None Outcome: None 効果: None None

対象集団: women with androgenetic alopecia (female pattern hair loss)

Randomized Controlled Trial n=14 26 weeks Double-blind
Randomized Controlled Trial Study to Evaluate the Efficacy of Combination Therapy with Diphenylcyclopropenone and Platelet-Rich …
Dose: Monthly PRP, 3 sessions vs: DPCP + placebo (same patient, other side) Outcome: SALT score 効果: 50% had >50% hair regrowth; no between-group diff None

対象集団: Patients with severe alopecia areata

review
The role of microtrauma in hair regrowth and regeneration in non-scarring alopecia.
Dose: Various microtrauma procedures: microneedling, fractional/non-fractional lasers, contact immunothera vs: Placebo 効果: Positive outcomes reported for hair density and thickness with microneedling, lasers, LLLT, and PRP None
Controlled Clinical Trial n=75 26 weeks
Intralesional Platelet-Rich Plasma Injection in Patients with Recalcitrant Alopecia Areata.
Dose: 3 sessions vs: Intralesional steroid (ILS) injections Outcome: SALT score at 6 months 効果: 83.4% very good response in PRP group p<0.001 for SALT6

対象集団: Patients with recalcitrant alopecia areata

Controlled Clinical Trial
Comparison of Efficacy of Autologous Platelet Rich Plasma Therapy With 5% Topical Minoxidil Spray in …
Dose: PRP vs 5% topical minoxidil vs: 5% topical minoxidil Outcome: Hair regrowth efficacy 効果: None None

対象集団: Patients with alopecia areata

Randomized Controlled Trial n=100 26 weeks Open-label
The Role of 5% Minoxidil <em>versus</em> Platelet-Rich Plasma in Treatment of Alopecia Areata.
Dose: Minoxidil 5% vs PRP vs: Topical minoxidil 5% Outcome: Hair regrowth (SALT score) 効果: None p<0.05

対象集団: Patients with alopecia areata

Key Statistics

89

研究数

2500

参加者数

Positive

A

グレード

Referenced Papers

International journal of … 2024 39 件の引用
Journal of cutaneous … 2024
Drug design, development … 2022 70 件の引用
Dermatology and therapy 2022 43 件の引用
The Journal of … 2022 28 件の引用
The journal of … 2022 22 件の引用
Journal of cosmetic … 2022 5 件の引用
Plastic and reconstructive … 2022 4 件の引用
Journal of cosmetic … 2022 1 件の引用
Clinical reviews in … 2021 304 件の引用
The Senior care … 2021 2 件の引用
The journal of … 2020 33 件の引用
Drugs 2020 33 件の引用
Dermatologic surgery : … 2020 32 件の引用
Journal of drugs … 2020 11 件の引用
Journal of the … 2020 10 件の引用
Dermatologic clinics 2019 7 件の引用
Dermatologic surgery : … 2019 5 件の引用
Journal of the … 2018 114 件の引用
Facial plastic surgery … 2018 43 件の引用
Dermatology online journal 2018
American journal of … 2017 32 件の引用
International journal of … 2015 79 件の引用
Expert opinion on … 2014 57 件の引用
Journal of nutrition … 2008 32 件の引用

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

一般的な使用量

hairloss:
3-4 sessions, 4-6 weeks apart

上限量: Not applicable

研究で検討された用量

用量 期間 効果 N
None -- Neutral --
Monthly PRP, 3 sessions 26 weeks Neutral 14
Various microtrauma procedures: microneedling, fractional/non-fractional lasers, contact immunothera -- Positive --
3 sessions 26 weeks Positive 75
PRP vs 5% topical minoxidil -- Positive --
Minoxidil 5% vs PRP 26 weeks Positive 100
Various regenerative methods -- Positive --
PRP + intralesional triamcinolone acetonide -- Positive 1

推奨摂取タイミング: In-clinic procedure; avoid washing hair for 24 hours after treatment

Safety & Side Effects

報告されている副作用

  • Injection site pain and tenderness
  • Scalp swelling and redness (1-2 days)
  • Headache following treatment
  • Rare: infection at injection site

既知の相互作用

  • NSAIDs and aspirin (discontinue 1 week before PRP; affect platelet function)
  • Anticoagulants (may increase bruising; consult physician)
  • Corticosteroid injections (may reduce PRP effectiveness)

耐容上限摂取量: Not applicable

サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。

Frequently Asked Questions

Does PRP療法 help with 円形脱毛症?
Based on 89 studies with 2,500 participants, there is strong evidence from multiple clinical trials that PRP療法 may support 円形脱毛症 management. Our evidence grade is A (Strong Evidence).
How much PRP療法 should I take for 円形脱毛症?
Studies have used various dosages. A commonly studied range is 3-4 sessions, 4-6 weeks apart. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of PRP療法?
Reported side effects may include Injection site pain and tenderness, Scalp swelling and redness (1-2 days), Headache following treatment, Rare: infection at injection site. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for PRP療法 and 円形脱毛症?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 89 peer-reviewed studies with 2,500 total participants. The overall direction of effect is positive.

Related Evidence

FDAに関する免責事項: これらの記述は米国食品医薬品局(FDA)による評価を受けていません。本ウェブサイトの製品および情報は、疾病の診断、治療、治癒、または予防を目的としたものではありません。表示されているエビデンスグレードは、公開された査読済み研究の分析に基づいており、医療上の助言を構成するものではありません。サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。