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Terapi PRP untuk Alopecia Areata

A Bukti Beberapa uji klinis besar secara konsisten menunjukkan manfaat yang signifikan.

Berdasarkan 21 studi (4 meta-analyses, 2 RCTs) dengan 2,376 peserta secara total. 18/21 studi menunjukkan efek positif.

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A

Kesimpulan

PRP therapy is well-supported by research as a procedure that may help stimulate hair regrowth in alopecia areata, with multiple meta-analyses confirming its potential benefits.

  • 86% of studies (18/21) show positive effects, backed by 4 meta-analyses
  • Multiple delivery methods studied: injection, microneedling, and laser-assisted
  • 2,376 participants across studies of varying design quality
  • Results may vary due to the unpredictable nature of autoimmune alopecia areata

Key Study Findings

Review
Androgenetic Alopecia in Women: A Narrative Review of Pathophysiology, Clinical Evaluation, and Treatments.
Dose: None vs: None Outcome: None Efek: None None

Populasi: women with androgenetic alopecia (female pattern hair loss)

Controlled Clinical Trial n=75 26 weeks
Intralesional Platelet-Rich Plasma Injection in Patients with Recalcitrant Alopecia Areata.
Dose: 3 sessions vs: Intralesional steroid (ILS) injections Outcome: SALT score at 6 months Efek: 83.4% very good response in PRP group p<0.001 for SALT6

Populasi: Patients with recalcitrant alopecia areata

Randomized Controlled Trial n=14 26 weeks Double-blind
Randomized Controlled Trial Study to Evaluate the Efficacy of Combination Therapy with Diphenylcyclopropenone and Platelet-Rich …
Dose: Monthly PRP, 3 sessions vs: DPCP + placebo (same patient, other side) Outcome: SALT score Efek: 50% had >50% hair regrowth; no between-group diff None

Populasi: Patients with severe alopecia areata

review
The role of microtrauma in hair regrowth and regeneration in non-scarring alopecia.
Dose: Various microtrauma procedures: microneedling, fractional/non-fractional lasers, contact immunothera vs: Placebo Efek: Positive outcomes reported for hair density and thickness with microneedling, lasers, LLLT, and PRP None
Systematic Review
Evaluating Anti-Inflammatory Potential of Platelet-Rich Plasma in Scarring Alopecia: A Systematic Review.
Dose: Platelet-rich plasma (PRP) vs: Various controls Outcome: Hair regrowth and inflammation reduction Efek: None None

Populasi: Patients with scarring alopecia

Controlled Clinical Trial
Comparison of Efficacy of Autologous Platelet Rich Plasma Therapy With 5% Topical Minoxidil Spray in …
Dose: PRP vs 5% topical minoxidil vs: 5% topical minoxidil Outcome: Hair regrowth efficacy Efek: None None

Populasi: Patients with alopecia areata

Key Statistics

89

Studi

2500

Peserta

Positive

A

Peringkat

Referenced Papers

International journal of … 2024 39 sitasi
Journal of cutaneous … 2024
Drug design, development … 2022 70 sitasi
The Journal of … 2022 28 sitasi
The journal of … 2022 22 sitasi
Journal of cosmetic … 2022 5 sitasi
Plastic and reconstructive … 2022 4 sitasi
Journal of cosmetic … 2022 1 sitasi
The Senior care … 2021 2 sitasi
Dermatologic surgery : … 2020 32 sitasi
Journal of drugs … 2020 11 sitasi
Journal of the … 2020 10 sitasi
Dermatologic clinics 2019 7 sitasi
Journal of the … 2018 114 sitasi
Facial plastic surgery … 2018 43 sitasi
Dermatology online journal 2018
American journal of … 2017 32 sitasi
Expert opinion on … 2014 57 sitasi

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosis yang Umum Digunakan

hairloss:
3-4 sessions, 4-6 weeks apart

Batas atas: Not applicable

Dosis yang Diteliti dalam Penelitian

Dosis Durasi Efek N
None -- Neutral --
3 sessions 26 weeks Positive 75
Monthly PRP, 3 sessions 26 weeks Neutral 14
Various microtrauma procedures: microneedling, fractional/non-fractional lasers, contact immunothera -- Positive --
Platelet-rich plasma (PRP) -- Positive --
PRP vs 5% topical minoxidil -- Positive --
Minoxidil 5% vs PRP 26 weeks Positive 100
Platelet-rich plasma (PRP) -- Positive --

Waktu terbaik diminum: In-clinic procedure; avoid washing hair for 24 hours after treatment

Safety & Side Effects

Efek Samping yang Dilaporkan

  • Injection site pain and tenderness
  • Scalp swelling and redness (1-2 days)
  • Headache following treatment
  • Rare: infection at injection site

Interaksi yang Diketahui

  • NSAIDs and aspirin (discontinue 1 week before PRP; affect platelet function)
  • Anticoagulants (may increase bruising; consult physician)
  • Corticosteroid injections (may reduce PRP effectiveness)

Asupan atas yang dapat ditoleransi: Not applicable

Selalu konsultasikan dengan tenaga kesehatan Anda sebelum memulai suplemen apa pun.Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai suplemen apa pun.

Frequently Asked Questions

Does Terapi PRP help with Alopecia Areata?
Based on 89 studies with 2,500 participants, there is strong evidence from multiple clinical trials that Terapi PRP may support Alopecia Areata management. Our evidence grade is A (Strong Evidence).
How much Terapi PRP should I take for Alopecia Areata?
Studies have used various dosages. A commonly studied range is 3-4 sessions, 4-6 weeks apart. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Terapi PRP?
Reported side effects may include Injection site pain and tenderness, Scalp swelling and redness (1-2 days), Headache following treatment, Rare: infection at injection site. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Terapi PRP and Alopecia Areata?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 89 peer-reviewed studies with 2,500 total participants. The overall direction of effect is positive.

References

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