コラーゲン ： 加齢性薄毛
A合計426名の参加者を対象とした5件の研究（RCT 1件を含む）に基づく。5件中5件の研究で肯定的な効果が示されている。
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A
結論
Collagen supplements show good evidence for supporting hair thickness and growth as part of an age-related hair thinning regimen, though it is usually studied in combination with other nutrients.
- All 5 studies report positive effects on hair growth and thickness
- Hydrolyzed collagen peptides may activate signaling pathways that support hair follicle health
- Collagen is often combined with other ingredients (iron, selenium, amino acids) in hair supplements
- Both marine and fish collagen have shown promise in laboratory and clinical studies
Key Study Findings
Prospective Open-Label Interventional Study
n=343
4 weeks
Open-label
Effect of a Hydrolyzed Collagen, Vitamin, and Zinc Containing Nutritional Supplement on Telogen Effluvium.
Dose: Pilopeptan Intensive (hydrolyzed collagen, Group B vitamins, zinc); daily for 1 month
vs: Placebo
効果: Significant improvements in all hair parameters at T1 and T2 (P < 0.001)
p<0.001
Review
Biomarker-Guided Dietary Supplementation: A Narrative Review of Precision in Personalized Nutrition.
Dose: None
vs: None
Outcome: Microbiome composition
効果: None
None
対象集団: None
randomized controlled trial
n=83
12 weeks
Efficacy and tolerability of an oral supplement containing amino acids, iron, selenium, and marine hydrolyzed …
Dose: 1 tablet per day (hydrolyzed fish-origin collagen 300 mg/dose) plus standard drug treatment
vs: Placebo
効果: GAS at week 12: Group A 1.67 ± 0.16 vs. Group B 0.66 ± 0.20 (p<0.001); 50% vs 23% achieved GAS ≥2
<0.001
Controlled Clinical Trial
n=843
4.3 weeks
Micronutrient Gaps and Supplement Use in a Diverse Cohort of Pregnant Women.
Dose: 91%
vs: None
Outcome: folate status
効果: None
None
対象集団: Pregnant women
Observational Study
n=701
Nutrient intakes from supplement and factors associated with supplement use among breast cancer survivors: A …
Dose: 66.5%
vs: None
Outcome: None
効果: None
None
対象集団: supplement use among breast cancer
Key Statistics
5
研究数
1970
参加者数
↑
Positive
A
グレード
Referenced Papers
International journal of …
2025
Biomarker-Guided Dietary Supplementation: A Narrative Review of Precision in Personalized Nutrition.
Review
Nutrients
2024
12 件の引用
Skin research and …
2023
11 件の引用
Nutrients
2023
11 件の引用
European journal of …
2021
5 件の引用
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
一般的な使用量
- general:
- 2.5-15 g/day
上限量： Not established
研究で検討された用量
| 用量 | 期間 | 効果 | N |
|---|---|---|---|
| Pilopeptan Intensive (hydrolyzed collagen, Group B vitamins, zinc); daily for 1 month | 4 weeks | Positive | 343 |
| None | -- | Positive | -- |
| 1 tablet per day (hydrolyzed fish-origin collagen 300 mg/dose) plus standard drug treatment | 12 weeks | Positive | 83 |
| 91% | 4.3 weeks | Positive | 843 |
| 66.5% | -- | Mixed | 701 |
推奨摂取タイミング： On an empty stomach or with vitamin C for enhanced collagen synthesis
Safety & Side Effects
報告されている副作用
- ⚠ Mild digestive discomfort (bloating, fullness)
- ⚠ Unpleasant taste (marine collagen)
- ⚠ Rare allergic reactions in individuals with fish or shellfish allergies
既知の相互作用
- ● No significant drug interactions established
- ● Calcium supplements (some collagen products contain added calcium)
耐容上限摂取量： Not established
サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。
Frequently Asked Questions
Does コラーゲン help with 加齢性薄毛?
Based on 5 studies with 1,970 participants, there is strong evidence from multiple clinical trials that コラーゲン may support 加齢性薄毛 management. Our evidence grade is A (Strong Evidence).
How much コラーゲン should I take for 加齢性薄毛?
Studies have used various dosages. A commonly studied range is 2.5-15 g/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of コラーゲン?
Reported side effects may include Mild digestive discomfort (bloating, fullness), Unpleasant taste (marine collagen), Rare allergic reactions in individuals with fish or shellfish allergies. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for コラーゲン and 加齢性薄毛?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 5 peer-reviewed studies with 1,970 total participants. The overall direction of effect is positive.
Related Evidence
に関する他の成分： 加齢性薄毛
FDAに関する免責事項: これらの記述は米国食品医薬品局（FDA）による評価を受けていません。本ウェブサイトの製品および情報は、疾病の診断、治療、治癒、または予防を目的としたものではありません。表示されているエビデンスグレードは、公開された査読済み研究の分析に基づいており、医療上の助言を構成するものではありません。サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。