Dutasteride untuk Alopecia Androgenetik
ABerdasarkan 43 studi (7 meta-analyses, 1 RCT) dengan 12,060 peserta secara total. 34/43 studi menunjukkan efek positif.
Kesimpulan
Dutasteride has strong scientific support for androgenetic alopecia and research suggests it may be more effective than finasteride, though it should be used under medical supervision due to potential side effects.
- 34 out of 43 studies show positive effects across 12,060 participants
- Multiple meta-analyses consistently support dutasteride's effectiveness for pattern hair loss
- Blocks both type I and type II 5-alpha reductase enzymes, potentially offering broader DHT reduction than finasteride
- Available in both oral and topical formulations, with topical forms being actively researched
Key Study Findings
Populasi: women with androgenetic alopecia (female pattern hair loss)
Populasi: Men with androgenetic alopecia
Populasi: Adult males with androgenetic alopecia
Populasi: 10 males + 10 postmenopausal females with resistant AGA
Key Statistics
99
Studi
19921
Peserta
Positive
Peringkat
Referenced Papers
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Dosis yang Umum Digunakan
- hairloss:
- 0.5 mg/day (off-label)
Batas atas: 0.5 mg/day
Dosis yang Diteliti dalam Penelitian
| Dosis | Durasi | Efek | N |
|---|---|---|---|
| None | -- | Neutral | -- |
| 0.2 mg dutasteride daily | 24 weeks | Positive | 139 |
| 3 sessions of dutasteride microinfusion (monthly) | 12 weeks | Positive | 8 |
| 4 monthly sessions of SPi + iontophoresis | 8 weeks | Positive | 20 |
| Dutasteride (oral, various doses) | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
Waktu terbaik diminum: Once daily at the same time, with or without food; prescription required
Safety & Side Effects
Efek Samping yang Dilaporkan
- ⚠ Decreased libido (more common than finasteride)
- ⚠ Erectile dysfunction
- ⚠ Ejaculation disorders
- ⚠ Gynecomastia (breast tissue growth)
- ⚠ Very long half-life (~5 weeks) means slow side effect resolution
Interaksi yang Diketahui
- ● CYP3A4 inhibitors (ketoconazole, ritonavir) may increase dutasteride levels
- ● May affect PSA levels (reduces by ~50%)
- ● Contraindicated in pregnancy (Category X teratogen)
Asupan atas yang dapat ditoleransi: 0.5 mg/day
Selalu konsultasikan dengan tenaga kesehatan Anda sebelum memulai suplemen apa pun.Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai suplemen apa pun.
Frequently Asked Questions
Does Dutasteride help with Alopecia Androgenetik?
How much Dutasteride should I take for Alopecia Androgenetik?
Are there side effects of Dutasteride?
How strong is the evidence for Dutasteride and Alopecia Androgenetik?
Related Evidence
Bahan lain untuk Alopecia Androgenetik
Penafian FDA: Pernyataan-pernyataan ini belum dievaluasi oleh Food and Drug Administration. Produk dan informasi di situs web ini tidak dimaksudkan untuk mendiagnosis, mengobati, menyembuhkan, atau mencegah penyakit apa pun. Peringkat bukti yang disajikan didasarkan pada analisis kami terhadap penelitian yang ditinjau sejawat dan tidak merupakan saran medis. Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai regimen suplemen apa pun.