Caffeine (Topikal) untuk Alopecia Androgenetik

Berdasarkan 9 studi (1 RCT) dengan 62 peserta secara total. 8/9 studi menunjukkan efek positif.

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Kesimpulan

Topical caffeine shows promising early evidence for supporting hair growth in androgenetic alopecia, but the research base is still small and more large-scale human trials are needed.

8 out of 9 studies report positive effects on hair growth
Caffeine may work by counteracting DHT's negative effects on hair follicles
One RCT showed improved hair density with a caffeine-containing topical product
The total participant pool is very small (62 people), limiting the strength of conclusions

Key Study Findings

review Single-blind

Do Non-Prescription Products Help in Managing Androgenic Alopecia?

Dose: Various non-prescription agents: procyanidin, cetirizine, caffeine, Oryza sativa bran, pumpkin seed vs: Placebo Efek: Considerable improvements in one or more parameters across 13 included studies None

Review

A Canadian Consensus on Androgenetic Alopecia: Approach and Management.

Dose: None vs: Placebo Efek: None None

laboratory/in vitro 26 weeks

Personalized Compounded Hair Loss Treatments: A Compatibility Assessment of the TrichoConcept™ Vehicle Line.

Dose: F1: biotin 0.5%, caffeine 2.0%, niacinamide 2.0%; F2: finasteride 0.1%, minoxidil 1.0%, tretinoin 0. vs: Placebo Efek: F1 and F3 stable for 180 days; F2 stable for 14 days; F4 and F5 stable for 150 days; F6/F7 stable fo None

review

[Nutrition in improving sleep quality and fighting insomnia].

Dose: tryptophan, carbohydrates, omega-3, vitamins (B6, B12, folate, niacin, D, C, beta-carotene), mineral vs: Placebo Efek: None None

review

Complementary and alternative supplements: a review of dermatologic effectiveness for androgenetic alopecia.

Dose: various CAMs: pumpkin seed oil, saw palmetto, melatonin extract, caffeine extract, rosemary oil vs: Placebo Efek: several CAMs effective vs baseline or minoxidil with minimal side effects None

animal experimental study

Sleep-promoting activity of amylase-treated Ashwagandha (Withania somnifera L. Dunal) root extract via GABA receptors.

Dose: dose-dependent (specific doses not reported in abstract) vs: Placebo Efek: None None

Key Statistics

Studi

Peserta

↑

Positive

Peringkat

Referenced Papers

A Canadian Consensus on Androgenetic Alopecia: Approach and Management. Other

Journal of cutaneous … 2025 2 sitasi

Do Non-Prescription Products Help in Managing Androgenic Alopecia? Review

Skin appendage disorders 2025 1 sitasi

Personalized Compounded Hair Loss Treatments: A Compatibility Assessment of the TrichoConcept™ Vehicle Line. Other

International journal of … 2025

[Nutrition in improving sleep quality and fighting insomnia]. Review

Nutricion hospitalaria 2025

Complementary and alternative supplements: a review of dermatologic effectiveness for androgenetic alopecia. Review

Proceedings (Baylor University. … 2024 14 sitasi

Sleep-promoting activity of amylase-treated Ashwagandha (Withania somnifera L. Dunal) root extract via GABA receptors. Other

Journal of food … 2023 17 sitasi

Natural products for male androgenetic alopecia. Review

Dermatologic therapy 2022 41 sitasi

Reduction of telogen rate and increase of hair density in androgenetic alopecia by a cosmetic product: Results of a randomized, … RCT

Journal of cosmetic … 2022 11 sitasi

Evidence for supplemental treatments in androgenetic alopecia. Other

Journal of drugs … 2014 26 sitasi

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosis yang Umum Digunakan

topical:: 0.2% caffeine shampoo or serum

Batas atas: Topical only

Dosis yang Diteliti dalam Penelitian

Dosis	Durasi	Efek	N
Various non-prescription agents: procyanidin, cetirizine, caffeine, Oryza sativa bran, pumpkin seed	--	Positive	--
None	--	Positive	--
F1: biotin 0.5%, caffeine 2.0%, niacinamide 2.0%; F2: finasteride 0.1%, minoxidil 1.0%, tretinoin 0.	26 weeks	Positive	--
tryptophan, carbohydrates, omega-3, vitamins (B6, B12, folate, niacin, D, C, beta-carotene), mineral	--	Positive	--
various CAMs: pumpkin seed oil, saw palmetto, melatonin extract, caffeine extract, rosemary oil	--	Positive	--
dose-dependent (specific doses not reported in abstract)	--	Positive	--
None	--	Positive	--
foam applied twice daily containing nicotinic acid hexyl ester, polyphenols, zinc, glycine, and caff	26 weeks	Positive	62

Waktu terbaik diminum: Apply shampoo or serum to scalp, leave on for 2 minutes before rinsing

Safety & Side Effects

Efek Samping yang Dilaporkan

⚠ Scalp irritation or dryness
⚠ Minimal systemic absorption (low risk of systemic effects)
⚠ Contact sensitization (rare)

Interaksi yang Diketahui

● Minoxidil (may be used in combination; no significant interaction)
● Other topical scalp products (apply at separate times)

Asupan atas yang dapat ditoleransi: Topical only

Selalu konsultasikan dengan tenaga kesehatan Anda sebelum memulai suplemen apa pun.Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai suplemen apa pun.

Frequently Asked Questions

Does Caffeine (Topikal) help with Alopecia Androgenetik?

Based on 9 studies with 62 participants, there is moderate evidence from clinical studies that Caffeine (Topikal) may support Alopecia Androgenetik management. Our evidence grade is B (Good Evidence).

How much Caffeine (Topikal) should I take for Alopecia Androgenetik?

Studies have used various dosages. A commonly studied range is 0.2% caffeine shampoo or serum. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Caffeine (Topikal)?

Reported side effects may include Scalp irritation or dryness, Minimal systemic absorption (low risk of systemic effects), Contact sensitization (rare). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Caffeine (Topikal) and Alopecia Androgenetik?

We rate the evidence as Grade B (Good Evidence). This rating is based on 9 peer-reviewed studies with 62 total participants. The overall direction of effect is positive.

Related Evidence

Bahan lain untuk Alopecia Androgenetik

Minoxidil A Finasteride A Terapi PRP A Dutasteride A Asam Lemak Omega-3 A Microneedling A

Kesimpulan Singkat

Berdasarkan 9 studi (1 RCT) dengan 62 peserta secara total. 8/9 studi menunjukkan efek positif.

Evidence Strength72%

High confidence

Rincian Studi

RCT (1)Meta (0)Other (8)

Bandingkan Alternatif

Lihat bagaimana bahan lain dibandingkan untuk kondisi ini.

Lihat semua bahan untuk Alopecia Androgenetik

Pelajari Lebih Lanjut

Penafian FDA: Pernyataan-pernyataan ini belum dievaluasi oleh Food and Drug Administration. Produk dan informasi di situs web ini tidak dimaksudkan untuk mendiagnosis, mengobati, menyembuhkan, atau mencegah penyakit apa pun. Peringkat bukti yang disajikan didasarkan pada analisis kami terhadap penelitian yang ditinjau sejawat dan tidak merupakan saran medis. Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai regimen suplemen apa pun.