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Iron for Telogen Effluvium

B

Based on 62 studies (2 RCTs) with 11,072 total participants. Results are mixed across studies.

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B

The Bottom Line

Iron may support recovery from telogen effluvium, particularly when low ferritin levels are confirmed, but the evidence is mixed and routine supplementation without testing is not well-supported.

  • 56 studies provide substantial evidence, though results are mixed across the research
  • Lower ferritin levels are commonly found in patients with telogen effluvium
  • One study found iron supplementation improved satisfaction even in patients without overtly low ferritin
  • Blood testing for ferritin and iron levels is recommended before starting supplementation

Key Study Findings

Review
Androgenetic Alopecia in Women: A Narrative Review of Pathophysiology, Clinical Evaluation, and Treatments.
Dose: None vs: None Outcome: None Effect: None None

Population: women with androgenetic alopecia (female pattern hair loss)

scoping_review n=16
A Scoping Review of Exosome Delivery Applications in Hair Loss.
Dose: variable; exosomes predominantly from mesenchymal stem cells (MSCs) vs: Placebo Effect: None None
Retrospective cohort n=2851
Retrospective Review of 2851 Female Patients With Telogen Effluvium: A Single-Center Experience.
Dose: None vs: Placebo Effect: Ferritin low in 46.5% of patients; iron deficiency in 29.5% p<0.05
review
The role of microtrauma in hair regrowth and regeneration in non-scarring alopecia.
Dose: Various microtrauma procedures: microneedling, fractional/non-fractional lasers, contact immunothera vs: Placebo Effect: Positive outcomes reported for hair density and thickness with microneedling, lasers, LLLT, and PRP None

Key Statistics

62

Studies

11072

Participants

Mixed

B

Grade

Referenced Papers

Journal of drugs … 2021 3 citations
Acta dermatovenerologica Croatica … 2016 6 citations
Journal of clinical … 2015 190 citations
The Medical clinics … 2015 66 citations
Clinical obstetrics and … 2015 9 citations
Turkish journal of … 2014 5 citations
Annals of gastroenterology 2014 5 citations
Skin pharmacology and … 2013 127 citations
Seminars in cutaneous … 2006 23 citations
American journal of … 2005 140 citations
Journal of the … 2005 64 citations
Revue medicale de … 2004
The Journal of … 2003 222 citations
International journal of … 2002 95 citations
Dermatologic clinics 1993 38 citations

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Commonly Used Dosages

general:
18 mg/day (women)
deficiency:
65-200 mg elemental iron/day

Upper limit: 45 mg/day

Dosages Studied in Research

Dosage Duration Effect N
None -- Neutral --
variable; exosomes predominantly from mesenchymal stem cells (MSCs) -- Positive 16
None -- Mixed --
None -- Neutral 2851
Various microtrauma procedures: microneedling, fractional/non-fractional lasers, contact immunothera -- Positive --
None -- Positive --
not applicable (observational; serum ferritin measured) -- Negative 100
None -- Mixed --

Best taken: On an empty stomach with vitamin C for best absorption; take 2 hours apart from calcium

Safety & Side Effects

Reported Side Effects

  • Constipation (most common)
  • Nausea and stomach cramps
  • Dark or black stools
  • Iron overload with excessive supplementation (hemochromatosis risk)

Known Interactions

  • Calcium supplements and dairy (reduce iron absorption by 50-60%)
  • Proton pump inhibitors (omeprazole) and H2 blockers reduce absorption
  • Tetracycline and quinolone antibiotics (mutual absorption reduction)
  • Levothyroxine (iron reduces thyroid hormone absorption)

Tolerable upper intake: 45 mg/day

Always consult your healthcare provider before starting any supplement.

Frequently Asked Questions

Does Iron help with Telogen Effluvium?
Based on 62 studies with 11,072 participants, there is moderate evidence from clinical studies that Iron may support Telogen Effluvium management. Our evidence grade is B (Good Evidence).
How much Iron should I take for Telogen Effluvium?
Studies have used various dosages. A commonly studied range is 18 mg/day (women). Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Iron?
Reported side effects may include Constipation (most common), Nausea and stomach cramps, Dark or black stools, Iron overload with excessive supplementation (hemochromatosis risk). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Iron and Telogen Effluvium?
We rate the evidence as Grade B (Good Evidence). This rating is based on 62 peer-reviewed studies with 11,072 total participants. The overall direction of effect is mixed.

Related Evidence

FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The products and information on this website are not intended to diagnose, treat, cure, or prevent any disease. The evidence grades presented are based on our analysis of published peer-reviewed research and do not constitute medical advice. Always consult your healthcare provider before starting any supplement regimen.