Terapia PRP para Alopecia Areata
ABasado en 21 estudios (4 meta-analyses, 2 RCTs) con 2,376 participantes en total. 18/21 estudios muestran efectos positivos.
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A
Conclusión
PRP therapy is well-supported by research as a procedure that may help stimulate hair regrowth in alopecia areata, with multiple meta-analyses confirming its potential benefits.
- 86% of studies (18/21) show positive effects, backed by 4 meta-analyses
- Multiple delivery methods studied: injection, microneedling, and laser-assisted
- 2,376 participants across studies of varying design quality
- Results may vary due to the unpredictable nature of autoimmune alopecia areata
Key Study Findings
Review
Androgenetic Alopecia in Women: A Narrative Review of Pathophysiology, Clinical Evaluation, and Treatments.
Dose: None
vs: None
Outcome: None
Efecto: None
None
Población: women with androgenetic alopecia (female pattern hair loss)
Randomized Controlled Trial
n=14
26 weeks
Double-blind
Randomized Controlled Trial Study to Evaluate the Efficacy of Combination Therapy with Diphenylcyclopropenone and Platelet-Rich …
Dose: Monthly PRP, 3 sessions
vs: DPCP + placebo (same patient, other side)
Outcome: SALT score
Efecto: 50% had >50% hair regrowth; no between-group diff
None
Población: Patients with severe alopecia areata
review
The role of microtrauma in hair regrowth and regeneration in non-scarring alopecia.
Dose: Various microtrauma procedures: microneedling, fractional/non-fractional lasers, contact immunothera
vs: Placebo
Efecto: Positive outcomes reported for hair density and thickness with microneedling, lasers, LLLT, and PRP
None
Controlled Clinical Trial
n=75
26 weeks
Intralesional Platelet-Rich Plasma Injection in Patients with Recalcitrant Alopecia Areata.
Dose: 3 sessions
vs: Intralesional steroid (ILS) injections
Outcome: SALT score at 6 months
Efecto: 83.4% very good response in PRP group
p<0.001 for SALT6
Población: Patients with recalcitrant alopecia areata
Controlled Clinical Trial
Comparison of Efficacy of Autologous Platelet Rich Plasma Therapy With 5% Topical Minoxidil Spray in …
Dose: PRP vs 5% topical minoxidil
vs: 5% topical minoxidil
Outcome: Hair regrowth efficacy
Efecto: None
None
Población: Patients with alopecia areata
Randomized Controlled Trial
n=100
26 weeks
Open-label
The Role of 5% Minoxidil <em>versus</em> Platelet-Rich Plasma in Treatment of Alopecia Areata.
Dose: Minoxidil 5% vs PRP
vs: Topical minoxidil 5%
Outcome: Hair regrowth (SALT score)
Efecto: None
p<0.05
Población: Patients with alopecia areata
Key Statistics
89
Estudios
2500
Participantes
↑
Positive
A
Calificación
Referenced Papers
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Evaluating Anti-Inflammatory Potential of Platelet-Rich Plasma in Scarring Alopecia: A Systematic Review.
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Platelet-Rich Plasma in Alopecia areata: A Case Report With a Mini Review of Literature.
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Reversible Hair Loss in Lichen Planopilaris: Regrowth With Low-Dose Naltrexone and Platelet-Rich Plasma.
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Systematic Review
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Platelet-Rich Plasma and its Use for Cicatricial and Non-Cicatricial Alopecias: A Narrative Review.
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2020
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The Utility of Platelet-Rich Plasma for the Treatment of Alopecia.
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2020
11 citas
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2020
10 citas
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7 citas
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5 citas
Expression of CD117 and platelet-derived growth factor receptor α in patients with alopecia areata.
Other
Indian journal of …
2020
Journal of cutaneous …
2019
50 citas
Journal of cosmetic …
2019
35 citas
Serum sickness disease in a patient with alopecia areata and Meniere' disease after PRP procedure.
Case Report
Dermatologic therapy
2019
17 citas
Dermatologic therapy
2019
16 citas
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2019
16 citas
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2019
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79 citas
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Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Dosificaciones de uso común
- hairloss:
- 3-4 sessions, 4-6 weeks apart
Límite superior: Not applicable
Dosificaciones estudiadas en la investigación
| Dosificación | Duración | Efecto | N |
|---|---|---|---|
| None | -- | Neutral | -- |
| Monthly PRP, 3 sessions | 26 weeks | Neutral | 14 |
| Various microtrauma procedures: microneedling, fractional/non-fractional lasers, contact immunothera | -- | Positive | -- |
| 3 sessions | 26 weeks | Positive | 75 |
| PRP vs 5% topical minoxidil | -- | Positive | -- |
| Minoxidil 5% vs PRP | 26 weeks | Positive | 100 |
| Various regenerative methods | -- | Positive | -- |
| PRP + intralesional triamcinolone acetonide | -- | Positive | 1 |
Mejor momento para tomar: In-clinic procedure; avoid washing hair for 24 hours after treatment
Safety & Side Effects
Efectos secundarios reportados
- ⚠ Injection site pain and tenderness
- ⚠ Scalp swelling and redness (1-2 days)
- ⚠ Headache following treatment
- ⚠ Rare: infection at injection site
Interacciones conocidas
- ● NSAIDs and aspirin (discontinue 1 week before PRP; affect platelet function)
- ● Anticoagulants (may increase bruising; consult physician)
- ● Corticosteroid injections (may reduce PRP effectiveness)
Ingesta máxima tolerable: Not applicable
Consulte siempre a su profesional de salud antes de comenzar cualquier suplemento.Siempre consulte a su profesional de salud antes de comenzar cualquier suplemento.
Frequently Asked Questions
Does Terapia PRP help with Alopecia Areata?
Based on 89 studies with 2,500 participants, there is strong evidence from multiple clinical trials that Terapia PRP may support Alopecia Areata management. Our evidence grade is A (Strong Evidence).
How much Terapia PRP should I take for Alopecia Areata?
Studies have used various dosages. A commonly studied range is 3-4 sessions, 4-6 weeks apart. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Terapia PRP?
Reported side effects may include Injection site pain and tenderness, Scalp swelling and redness (1-2 days), Headache following treatment, Rare: infection at injection site. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Terapia PRP and Alopecia Areata?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 89 peer-reviewed studies with 2,500 total participants. The overall direction of effect is positive.
Related Evidence
Otros ingredientes para Alopecia Areata
Terapia PRP para otras condiciones
Aviso legal FDA: Estas declaraciones no han sido evaluadas por la Food and Drug Administration. Los productos y la información en este sitio web no están destinados a diagnosticar, tratar, curar ni prevenir ninguna enfermedad. Las calificaciones de evidencia presentadas se basan en nuestro análisis de investigación publicada revisada por pares y no constituyen consejo médico. Siempre consulte a su profesional de salud antes de comenzar cualquier régimen de suplementos.