Platelet-Rich Plasma as a Treatment for Androgenetic Alopecia.

Aditya K Gupta, John Cole, David P Deutsch, Peter A Everts, Robert P Niedbalski et al.

Meta-Analysis Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 2019 68 citações

PubMed DOI

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Study Design

Tipo de Estudo: Meta-Analysis
População: None
Duração: 26.0 weeks

Intervenção: Platelet-Rich Plasma as a Treatment for Androgenetic Alopecia. None
Comparador: Placebo
Desfecho Primário: Hair growth/density
Direção do Efeito: Positive
Risco de Viés: Unclear

Abstract

BACKGROUND: Platelet-rich plasma (PRP) treatment may encourage hair growth by promoting cellular maturation, differentiation, and proliferation. OBJECTIVE: The objective of this study was to evaluate the effectiveness of PRP as a treatment for androgenetic alopecia (AGA). MATERIALS AND METHODS: A literature search combined with meta-analysis was used to calculate the overall standardized mean difference (SMD) in hair density in patients treated with PRP injections in comparison with baseline and placebo treatment. Chi squared analysis and Fisher exact test were used to investigate variation in protocols. RESULTS: The overall SMD in hair density was 0.58 (95% confidence interval [CI]: 0.35-0.80) and 0.51 (95% CI: 0.23-0.80, p < .0004) in favor of PRP treatment when compared with baseline and placebo treatment, respectively. CONCLUSION: Platelet-rich plasma is beneficial in the treatment of AGA. It is recommended that 3 monthly sessions of PRP (once monthly ×3 treatments) be used followed by a 3- to 6-month maintenance period.

Resumo Rápido

Platelet-rich plasma is beneficial in the treatment of AGA and it is recommended that 3 monthly sessions of PRP be used followed by a 3- to 6-month maintenance period.

Used In Evidence Reviews

A Terapia PRP para Alopecia Androgenética

Platelet-Rich Plasma as a Treatment for Androgenetic Alopecia.

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Study Design

Abstract

Resumo Rápido

Used In Evidence Reviews

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