Terapia PRP per Alopecia areata
ABasato su 21 studi (4 meta-analyses, 2 RCTs) con 2,376 partecipanti totali. 18/21 studi mostrano effetti positivi.
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A
In sintesi
PRP therapy is well-supported by research as a procedure that may help stimulate hair regrowth in alopecia areata, with multiple meta-analyses confirming its potential benefits.
- 86% of studies (18/21) show positive effects, backed by 4 meta-analyses
- Multiple delivery methods studied: injection, microneedling, and laser-assisted
- 2,376 participants across studies of varying design quality
- Results may vary due to the unpredictable nature of autoimmune alopecia areata
Key Study Findings
Review
Androgenetic Alopecia in Women: A Narrative Review of Pathophysiology, Clinical Evaluation, and Treatments.
Dose: None
vs: None
Outcome: None
Effetto: None
None
Popolazione: women with androgenetic alopecia (female pattern hair loss)
Randomized Controlled Trial
n=14
26 weeks
Double-blind
Randomized Controlled Trial Study to Evaluate the Efficacy of Combination Therapy with Diphenylcyclopropenone and Platelet-Rich …
Dose: Monthly PRP, 3 sessions
vs: DPCP + placebo (same patient, other side)
Outcome: SALT score
Effetto: 50% had >50% hair regrowth; no between-group diff
None
Popolazione: Patients with severe alopecia areata
review
The role of microtrauma in hair regrowth and regeneration in non-scarring alopecia.
Dose: Various microtrauma procedures: microneedling, fractional/non-fractional lasers, contact immunothera
vs: Placebo
Effetto: Positive outcomes reported for hair density and thickness with microneedling, lasers, LLLT, and PRP
None
Controlled Clinical Trial
n=75
26 weeks
Intralesional Platelet-Rich Plasma Injection in Patients with Recalcitrant Alopecia Areata.
Dose: 3 sessions
vs: Intralesional steroid (ILS) injections
Outcome: SALT score at 6 months
Effetto: 83.4% very good response in PRP group
p<0.001 for SALT6
Popolazione: Patients with recalcitrant alopecia areata
Controlled Clinical Trial
Comparison of Efficacy of Autologous Platelet Rich Plasma Therapy With 5% Topical Minoxidil Spray in …
Dose: PRP vs 5% topical minoxidil
vs: 5% topical minoxidil
Outcome: Hair regrowth efficacy
Effetto: None
None
Popolazione: Patients with alopecia areata
Randomized Controlled Trial
n=100
26 weeks
Open-label
The Role of 5% Minoxidil <em>versus</em> Platelet-Rich Plasma in Treatment of Alopecia Areata.
Dose: Minoxidil 5% vs PRP
vs: Topical minoxidil 5%
Outcome: Hair regrowth (SALT score)
Effetto: None
p<0.05
Popolazione: Patients with alopecia areata
Key Statistics
89
Studi
2500
Partecipanti
↑
Positive
A
Grado
Referenced Papers
American journal of …
2026
International journal of …
2025
Italian journal of …
2025
Sisli Etfal Hastanesi …
2025
International journal of …
2024
39 citazioni
Lasers in medical …
2024
10 citazioni
British journal of …
2024
9 citazioni
Evaluating Anti-Inflammatory Potential of Platelet-Rich Plasma in Scarring Alopecia: A Systematic Review.
Systematic Review
Journal of drugs …
2024
3 citazioni
Cureus
2024
3 citazioni
Journal of the …
2024
2 citazioni
Regenerative medicine in the treatment of specific dermatologic disorders: a systematic review of randomized controlled clinical trials.
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Platelet-rich plasma for the treatment of alopecia: a systematic review and meta-analysis.
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Platelet-Rich Plasma in Alopecia areata: A Case Report With a Mini Review of Literature.
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Regenerative medicine strategies for hair growth and regeneration: A narrative review of literature.
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7 citazioni
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7 citazioni
Reversible Hair Loss in Lichen Planopilaris: Regrowth With Low-Dose Naltrexone and Platelet-Rich Plasma.
Case Report
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2022
6 citazioni
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2022
5 citazioni
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2022
4 citazioni
Plastic and reconstructive …
2022
4 citazioni
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1 citazioni
Platelet Rich Plasma for the Treatment of Scarring Alopecia Due to Discoid Lupus Erythematosus.
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2022
1 citazioni
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2022
1 citazioni
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2021
315 citazioni
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2021
304 citazioni
Alopecia areata: a review on diagnosis, immunological etiopathogenesis and treatment options.
Review
Clinical and experimental …
2021
130 citazioni
Systematic review of platelet-rich plasma in treating alopecia: Focusing on efficacy, safety, and therapeutic durability.
Systematic Review
Dermatologic therapy
2021
52 citazioni
Dermatologic clinics
2021
22 citazioni
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16 citazioni
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14 citazioni
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10 citazioni
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8 citazioni
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2 citazioni
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2020
37 citazioni
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2020
33 citazioni
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2020
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33 citazioni
Platelet-Rich Plasma and Its Utilities in Alopecia: A Systematic Review.
Systematic Review
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2020
32 citazioni
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28 citazioni
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2020
26 citazioni
Platelet-Rich Plasma and its Use for Cicatricial and Non-Cicatricial Alopecias: A Narrative Review.
Review
Dermatology and therapy
2020
24 citazioni
Acta dermatovenerologica Alpina, …
2020
24 citazioni
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2020
21 citazioni
Journal of cutaneous …
2020
21 citazioni
Dermatologic therapy
2020
18 citazioni
Aesthetic surgery journal
2020
13 citazioni
Cureus
2020
11 citazioni
The Utility of Platelet-Rich Plasma for the Treatment of Alopecia.
Systematic Review
Journal of drugs …
2020
11 citazioni
Journal of the …
2020
10 citazioni
Cureus
2020
7 citazioni
The journal of …
2020
5 citazioni
Expression of CD117 and platelet-derived growth factor receptor α in patients with alopecia areata.
Other
Indian journal of …
2020
Journal of cutaneous …
2019
50 citazioni
Journal of cosmetic …
2019
35 citazioni
Serum sickness disease in a patient with alopecia areata and Meniere' disease after PRP procedure.
Case Report
Dermatologic therapy
2019
17 citazioni
Dermatologic therapy
2019
16 citazioni
The Journal of …
2019
16 citazioni
Journal of cosmetic …
2019
13 citazioni
What's New in Hair Loss.
Review
Dermatologic clinics
2019
7 citazioni
Emerging Nonsteroid-Based Procedural Therapies for Alopecia Areata: A Systematic Review.
Systematic Review
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2019
5 citazioni
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107 citazioni
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Systematic Review
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34 citazioni
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2017
32 citazioni
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2017
1 citazioni
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2016
3 citazioni
International journal of …
2015
79 citazioni
Indian journal of …
2015
74 citazioni
JAAD case reports
2015
40 citazioni
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2014
57 citazioni
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279 citazioni
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32 citazioni
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Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Dosaggi di uso comune
- hairloss:
- 3-4 sessions, 4-6 weeks apart
Limite massimo: Not applicable
Dosaggi studiati nella ricerca
| Dosaggio | Durata | Effetto | N |
|---|---|---|---|
| None | -- | Neutral | -- |
| Monthly PRP, 3 sessions | 26 weeks | Neutral | 14 |
| Various microtrauma procedures: microneedling, fractional/non-fractional lasers, contact immunothera | -- | Positive | -- |
| 3 sessions | 26 weeks | Positive | 75 |
| PRP vs 5% topical minoxidil | -- | Positive | -- |
| Minoxidil 5% vs PRP | 26 weeks | Positive | 100 |
| Various regenerative methods | -- | Positive | -- |
| PRP + intralesional triamcinolone acetonide | -- | Positive | 1 |
Momento migliore per l'assunzione: In-clinic procedure; avoid washing hair for 24 hours after treatment
Safety & Side Effects
Effetti collaterali segnalati
- ⚠ Injection site pain and tenderness
- ⚠ Scalp swelling and redness (1-2 days)
- ⚠ Headache following treatment
- ⚠ Rare: infection at injection site
Interazioni note
- ● NSAIDs and aspirin (discontinue 1 week before PRP; affect platelet function)
- ● Anticoagulants (may increase bruising; consult physician)
- ● Corticosteroid injections (may reduce PRP effectiveness)
Livello di assunzione massimo tollerabile: Not applicable
Consultare sempre il proprio medico prima di iniziare qualsiasi integratore.Consultate sempre il vostro medico prima di iniziare qualsiasi integratore.
Frequently Asked Questions
Does Terapia PRP help with Alopecia areata?
Based on 89 studies with 2,500 participants, there is strong evidence from multiple clinical trials that Terapia PRP may support Alopecia areata management. Our evidence grade is A (Strong Evidence).
How much Terapia PRP should I take for Alopecia areata?
Studies have used various dosages. A commonly studied range is 3-4 sessions, 4-6 weeks apart. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Terapia PRP?
Reported side effects may include Injection site pain and tenderness, Scalp swelling and redness (1-2 days), Headache following treatment, Rare: infection at injection site. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Terapia PRP and Alopecia areata?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 89 peer-reviewed studies with 2,500 total participants. The overall direction of effect is positive.
Related Evidence
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Terapia PRP per altre condizioni
Avvertenza FDA: Queste affermazioni non sono state valutate dalla Food and Drug Administration. I prodotti e le informazioni presenti su questo sito web non sono destinati a diagnosticare, trattare, curare o prevenire alcuna malattia. I gradi di evidenza presentati si basano sulla nostra analisi della ricerca pubblicata e sottoposta a revisione paritaria e non costituiscono consulenza medica. Consultate sempre il vostro medico prima di iniziare qualsiasi regime di integrazione.