Microneedling combined with compound betamethasone in treatment of severe alopecia areata: A case report.
Study Design
- Jenis Studi
- case report
- Ukuran Sampel
- 1
- Durasi
- 24 weeks
- Intervensi
- Microneedling combined with compound betamethasone in treatment of severe alopecia areata: A case report. microneedling + compound betamethasone; treatment over 6 months
- Pembanding
- Placebo
- Arah Efek
- Positive
- Risiko Bias
- High
Abstract
Alopecia areata (AA) is a common inflammatory, non-cicatricial hair loss. At present, it is considered that its pathogenesis is an autoimmune disease specific to hair follicle organs mediated by T cells under the combined action of genetic and environmental factors. Treatment is challenging for children with severe AA who are resistant or intolerant to conventional treatment.Here, we treated a 3-year-old child with severe AA with microneedling combined with compound betamethasone. After 6 months of treatment, the patient's condition was significantly improved, and most of the primary hair loss areas had hair regeneration.
Full Text
Figures
Figure 1
Clinical photographs or study design for a trial combining microneedling with compound betamethasone injection for treating severe alopecia areata.
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Figure 2
Treatment response data showing hair regrowth outcomes in patients receiving microneedling combined with betamethasone, compared to standard therapy.
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Figure 3
Before-and-after images or quantitative assessment of hair regrowth in severe alopecia areata patients treated with the microneedling-betamethasone combination protocol.
photographTables
Table 1
| Author | Age, gender, and medical history | AA type and scale | Microneedling import drug type | Microneedling treatment frequency | Other treatments | Curative effect | Previous treatment |
|---|---|---|---|---|---|---|---|
| Asad, et al. ( | 58, male, 3 months | ophiasis, moderate | Triamcinolone, | once every 30 days, 4 times | topical clobetasol 0.05% solution twice daily | At week 24, the hair completely regenerated | – |
| Beergouder, et al. ( | 11,female, 2 years | alopecia totalis,severe | Triamcinolone, 10mg/ml | once every 20 days, 3 times | minoxidil 2% at night. | At week 12, the hair completely regenerated | a tapering dose of steroids for few days, |
| Chandrashekar B, et al. ( | female,(age unknown),1 years | multiple patches, mild | Triamcinolone, 10mg/ml | once every 21 days, 3 times | – | At week 6, hair regeneration was about 95% | intralesional injections of |
| Chandrashekar, et al. ( | male,(age unknown), 6 months | multiple patches, severe | Triamcinolone, 10mg/ml | once every 21 days, 3 times | – | At week 21, the hair completely regenerated |
References
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