Excessive oral zinc supplementation.

Mark B Salzman, Elaine M Smith, Charles Koo

Case Report Journal of pediatric hematology/oncology 2002 80 citations

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Study Design

Type d'étude: Case Reports
Taille de l'échantillon: 1
Population: 17-year-old boy self-treating acne with excess zinc
Durée: 26 weeks

Intervention: Excessive oral zinc supplementation. Large daily doses of zinc supplements
Comparateur: None
Critère de jugement principal: Zinc-induced copper deficiency
Direction de l'effet: Negative
Risque de biais: High

Abstract

The use of megadoses of vitamin and mineral supplements has become common. The authors describe a 17-year-old boy who presented with fatigue after taking large daily doses of zinc supplements for 6 to 7 months in an attempt to treat his acne. A zinc-induced hypocupremia developed, causing anemia, leukopenia, and neutropenia. Anemia and neutropenia resolved 6 months after he stopped taking the zinc. Excessive zinc intake can have toxic effects, and questions about patients' use of vitamin and mineral supplements should be asked when medication histories are taken.

En bref

A 17-year-old boy who presented with fatigue after taking large daily doses of zinc supplements for 6 to 7 months in an attempt to treat his acne was described, causing anemia, leukopenia, and neutropenia.

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Excessive oral zinc supplementation.

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Abstract

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