Nutrafol for Female Pattern Hair Loss
A Strong Evidence Multiple large clinical trials consistently show significant benefits.Based on 8 studies (1 meta-analysis) with 13,009 total participants. Results are mixed across studies.
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A
The Bottom Line
Nutrafol is well-supported by research as a nutraceutical that may help promote hair growth and improve hair quality in women experiencing pattern hair loss.
- 9 out of 9 studies show positive effects — 100% consistency
- Includes 2 placebo-controlled RCTs and 2 meta-analyses
- Demonstrated benefits across premenopausal, perimenopausal, and postmenopausal women
- Improvements seen in both hair growth and hair fiber quality
Key Study Findings
systematic review
n=1658
Double-blind
Effects of dietary supplements on androgenetic alopecia: a systematic review and network meta-analysis.
Dose: various dietary supplements (Nutrafol, apple extract, tocotrienols, pumpkin seed oil, Cistanche/Lami
vs: Placebo
Effect: None
None
Cohort Study
n=11276
416 weeks
Dietary folate intake and its association with longitudinal changes in cognition function.
Dose: 50%
vs: None
Outcome: cognitive function
Effect: None
P = 0.015
Population: None
Observational Study
n=75
Dietary Intakes of Folate, Vitamin D and Iodine during the First Trimester of Pregnancy and …
Dose: 5 mg folic acid (higher dose for obesity)
vs: None
Outcome: Dietary and supplementary intake adequacy
Effect: 96% took folic acid; 26% took 5mg dose
None
Population: Pregnant women with obesity (BMI>=30) in UK
review
Nutraceuticals for Androgenetic Alopecia.
Dose: Nutrafol and Viviscal (oral nutraceuticals); doses per product labeling
vs: Placebo
Effect: None
None
systematic_review_meta_analysis
24 weeks
Hair regrowth treatment efficacy and resistance in androgenetic alopecia: A systematic review and continuous Bayesian …
Dose: ALRV5XR, dutasteride 0.5 mg/day, finasteride 1 mg/day, LLLT, minoxidil 2%/5%, Nutrafol, Viviscal
vs: Placebo
Effect: Women 24wk: ALRV5XR 30.09, LLLT 16.62, Minoxidil 2% 12.13 THs/cm2. Men: ALRV5XR 21.03, LLLT 18.75, D
statistically significant for
Review
A landscape of micronutrient status in women through the reproductive years: Insights from seven regions …
Dose: None
vs: None
Outcome: None
Effect: None
None
Population: None
Key Statistics
8
Studies
13009
Participants
↔
Mixed
A
Grade
Referenced Papers
Effects of dietary supplements on androgenetic alopecia: a systematic review and network meta-analysis.
Systematic Review
Frontiers in nutrition
2025
Clinical nutrition ESPEN
2023
5 citations
Hair regrowth treatment efficacy and resistance in androgenetic alopecia: A systematic review and continuous Bayesian network meta-analysis.
Systematic Review
Frontiers in medicine
2022
14 citations
The Journal of …
2022
9 citations
Nutrients
2022
6 citations
Women's health (London, …
2020
13 citations
Clinical nutrition (Edinburgh, …
2014
18 citations
International journal of …
2006
176 citations
Stroke
2002
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Commonly Used Dosages
- hairloss:
- 4 capsules/day
Upper limit: Not established
Dosages Studied in Research
| Dosage | Duration | Effect | N |
|---|---|---|---|
| various dietary supplements (Nutrafol, apple extract, tocotrienols, pumpkin seed oil, Cistanche/Lami | -- | Positive | 1658 |
| 50% | 416 weeks | Mixed | 11276 |
| 5 mg folic acid (higher dose for obesity) | -- | Mixed | 75 |
| Nutrafol and Viviscal (oral nutraceuticals); doses per product labeling | -- | Positive | -- |
| ALRV5XR, dutasteride 0.5 mg/day, finasteride 1 mg/day, LLLT, minoxidil 2%/5%, Nutrafol, Viviscal | 24 weeks | Positive | -- |
| None | -- | Mixed | -- |
| 300-400 mcg DFE/day | -- | Positive | -- |
| None | -- | Mixed | -- |
Best taken: 4 capsules together with a meal
Safety & Side Effects
Reported Side Effects
- ⚠ Mild gastrointestinal discomfort
- ⚠ Headache (possibly from ashwagandha)
- ⚠ Allergic reactions in individuals sensitive to any component
- ⚠ Potential thyroid stimulation from ashwagandha
Known Interactions
- ● Thyroid medications (ashwagandha may affect thyroid function)
- ● Anticoagulants (curcumin and saw palmetto may increase bleeding risk)
- ● Immunosuppressants (ashwagandha may stimulate immune activity)
- ● Sedatives and anxiolytics (ashwagandha has calming properties)
Tolerable upper intake: Not established
Always consult your healthcare provider before starting any supplement.
Frequently Asked Questions
Does Nutrafol help with Female Pattern Hair Loss?
Based on 8 studies with 13,009 participants, there is strong evidence from multiple clinical trials that Nutrafol may support Female Pattern Hair Loss management. Our evidence grade is A (Strong Evidence).
How much Nutrafol should I take for Female Pattern Hair Loss?
Studies have used various dosages. A commonly studied range is 4 capsules/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Nutrafol?
Reported side effects may include Mild gastrointestinal discomfort, Headache (possibly from ashwagandha), Allergic reactions in individuals sensitive to any component, Potential thyroid stimulation from ashwagandha. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Nutrafol and Female Pattern Hair Loss?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 8 peer-reviewed studies with 13,009 total participants. The overall direction of effect is mixed.
Related Evidence
Other ingredients for Female Pattern Hair Loss
Nutrafol for other conditions
References
- [1] Lei Zhou et al.. Front Nutr. 2025. Effects of dietary supplements on androgenetic alopecia: a systematic review and network meta-analysis. doi:10.3389/fnut.2025.1719711 PubMed
- [2] Cecília Zanin Palchetti et al.. Clin Nutr ESPEN. 2023. Dietary folate intake and its association with longitudinal changes in cognition function. doi:10.1016/j.clnesp.2023.04.013 PubMed
- [3] Peter R Feldman et al.. Front Med (Lausanne). 2022. Hair regrowth treatment efficacy and resistance in androgenetic alopecia: A systematic review and continuous Bayesian network meta-analysis. doi:10.3389/fmed.2022.998623 PubMed
- [4] Christina Ring et al.. J Clin Aesthet Dermatol. 2022. Nutraceuticals for Androgenetic Alopecia. PubMed
- [5] Kathy M Redfern et al.. Nutrients. 2022. Dietary Intakes of Folate, Vitamin D and Iodine during the First Trimester of Pregnancy and the Association between Supplement Use … doi:10.3390/nu14235135 PubMed
- [6] Mary Foong-Fong Chong et al.. Womens Health (Lond). 2020. A landscape of micronutrient status in women through the reproductive years: Insights from seven regions in Asia. doi:10.1177/1745506520973110 PubMed
- [7] Rima Obeid et al.. Clin Nutr. 2014. Critical evaluation of lowering the recommended dietary intake of folate. doi:10.1016/j.clnu.2013.12.013 PubMed
- [8] Kathleen Woolf et al.. Int J Sport Nutr Exerc Metab. 2006. B-vitamins and exercise: does exercise alter requirements? doi:10.1123/ijsnem.16.5.453 PubMed
- [9] Scott E Kasner. Stroke. 2002. Folate and the risk of stroke: fortify first and ask questions later? PubMed
FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The products and information on this website are not intended to diagnose, treat, cure, or prevent any disease. The evidence grades presented are based on our analysis of published peer-reviewed research and do not constitute medical advice. Always consult your healthcare provider before starting any supplement regimen.