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Physiology and Medical Treatments for Alopecia.

Tymon Tai, Amit Kochhar
Review Facial plastic surgery clinics of North America 2020 15 Zitierungen
PubMed DOI
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Study Design

Studientyp
Review
Population
Androgenetic alopecia patients
Intervention
Physiology and Medical Treatments for Alopecia. None
Vergleichsgruppe
None
Primärer Endpunkt
None
Wirkungsrichtung
Mixed
Verzerrungsrisiko
Unclear

Abstract

Androgenetic alopecia (AGA) is the most common hair loss disorder in men and women. The characteristic and reproducible balding pattern in AGA negatively affects self-image and the external perceptions of the balding patient. The phenotypical changes are driven by dihydrotestosterone (DHT) and its precursor testosterone. DHT induces follicle miniaturization and hair cycle changes until resulting hairs no longer extrude through the skin surface. AGA is inherited in a polygenetic pattern and is susceptible to epigenetic and environmental factors. Currently, minoxidil, finasteride, and photolaser therapy are the only Food and Drug Administration-approved medical treatments for AGA.

Zusammenfassung

Current treatment options for AGA include minoxidil, finasteride, and photolaser therapy, which are the only Food and Drug Administration-approved medical treatments for AGA.

Used In Evidence Reviews

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