Platelet-Rich Plasma as a Treatment for Androgenetic Alopecia.

Aditya K Gupta, John Cole, David P Deutsch, Peter A Everts, Robert P Niedbalski et al.

Meta-Analysis Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 2019 68 次引用

PubMed DOI

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Study Design

研究类型: Meta-Analysis
研究人群: None
持续时间: 26.0 weeks

干预措施: Platelet-Rich Plasma as a Treatment for Androgenetic Alopecia. None
对照组: Placebo
主要结局: Hair growth/density
效应方向: Positive
偏倚风险: Unclear

Abstract

BACKGROUND: Platelet-rich plasma (PRP) treatment may encourage hair growth by promoting cellular maturation, differentiation, and proliferation. OBJECTIVE: The objective of this study was to evaluate the effectiveness of PRP as a treatment for androgenetic alopecia (AGA). MATERIALS AND METHODS: A literature search combined with meta-analysis was used to calculate the overall standardized mean difference (SMD) in hair density in patients treated with PRP injections in comparison with baseline and placebo treatment. Chi squared analysis and Fisher exact test were used to investigate variation in protocols. RESULTS: The overall SMD in hair density was 0.58 (95% confidence interval [CI]: 0.35-0.80) and 0.51 (95% CI: 0.23-0.80, p < .0004) in favor of PRP treatment when compared with baseline and placebo treatment, respectively. CONCLUSION: Platelet-rich plasma is beneficial in the treatment of AGA. It is recommended that 3 monthly sessions of PRP (once monthly ×3 treatments) be used followed by a 3- to 6-month maintenance period.

简要概述

Platelet-rich plasma is beneficial in the treatment of AGA and it is recommended that 3 monthly sessions of PRP be used followed by a 3- to 6-month maintenance period.

Used In Evidence Reviews

A PRP 疗法用于雄激素性脱发

Platelet-Rich Plasma as a Treatment for Androgenetic Alopecia.

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Study Design

Abstract

简要概述

Used In Evidence Reviews

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