Androgens and hair loss.

Adel Alsantali, Jerry Shapiro

Review Current opinion in endocrinology, diabetes, and obesity 2009 54 次引用

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研究类型: Review
研究人群: None

干预措施: Androgens and hair loss. None
对照组: None
主要结局: Androgens and hair loss.
效应方向: Positive
偏倚风险: Unclear

Abstract

PURPOSE OF REVIEW: Androgenetic alopecia (AGA) or male pattern hair loss is a very common condition that has a significant psychosocial impact for patients. Many advances in the pathogenesis and treatment of AGA have been discovered recently. We discuss the pathogenesis and treatment of AGA. RECENT FINDINGS: Wide genome analysis showed an association of AGA and chromosome 20pll in addition to androgen-receptor gene. Also, a locus on chromosome 3q26 was found to have a linkage with AGA. Dutasteride has been shown to be more effective than finasteride in the treatment of AGA but is not yet a recommended therapy. In an in-vitro study, a new topical liposomal finasteride formulation showed more than five-fold higher deposition of drug in skin than the corresponding plain drug solution. SUMMARY: These recent developments in the field of AGA hold some promise and may play a role in the future management.

简要概述

The pathogenesis and treatment of AGA is discussed and a new topical liposomal finasteride formulation showed more than five-fold higher deposition of drug in skin than the corresponding plain drug solution.

Used In Evidence Reviews

A 米诺地尔（Minoxidil）用于雄激素性脱发

A 非那雄胺（Finasteride）用于雄激素性脱发

A 度他雄胺（Dutasteride）用于雄激素性脱发

Androgens and hair loss.

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Study Design

Abstract

简要概述

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