铁用于缺铁性脱发

Q: Does 铁 help with 缺铁性脱发?

Based on 73 studies with 30,034 participants, there is strong evidence from multiple clinical trials that 铁 may support 缺铁性脱发 management. Our evidence grade is A (Strong Evidence).

Q: How much 铁 should I take for 缺铁性脱发?

Studies have used various dosages. A commonly studied range is 18 mg/day (women). Always consult your healthcare provider before starting any supplement regimen.

Q: Are there side effects of 铁?

Reported side effects may include Constipation (most common), Nausea and stomach cramps, Dark or black stools, Iron overload with excessive supplementation (hemochromatosis risk). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

Q: How strong is the evidence for 铁 and 缺铁性脱发?

We rate the evidence as Grade A (Strong Evidence). This rating is based on 73 peer-reviewed studies with 30,034 total participants. The overall direction of effect is mixed.

基于73项研究（4项荟萃分析），共30,034名参与者。各研究结果不一。

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结论

Iron deficiency is clearly linked to hair loss, and correcting a genuine deficiency may support hair regrowth, but iron supplementation is not universally effective for all types of hair loss.

73 studies across 30,034 participants provide extensive evidence on the iron-hair loss connection
Low serum ferritin levels are frequently observed in patients with hair loss
Supplementation appears most beneficial when a true iron deficiency is documented
Iron supplementation without confirmed deficiency may not improve hair outcomes and can carry risks

Key Study Findings

review

[Restless leg syndrome. Diagnosis and treatment].

Dose: various vs: Placebo 效果: None None

case-control n=90

Restless Leg Syndrome and Association with Serum NT Pro-CNP.

Dose: None vs: Placebo 效果: NT pro-CNP significantly lower in RLS vs controls; sensitivity 80%, specificity 88.9%; serum iron lo None

Review

Iron Metabolism and the Role of Iron Therapy in Pediatric Restless Leg Syndrome.

Dose: None vs: Placebo 效果: None None

cross-sectional n=150

Prevalence of Restless Leg Syndrome and Its Association With Iron Deficiency in Patients With Chronic …

Dose: None vs: Placebo 效果: RLS prevalence 42%; serum ferritin lower in RLS (88.4 vs 126.7 ng/mL); TSAT lower (16.3% vs 22.1%); p < 0.01

review

Restless Leg Syndrome and Pregnancy.

Dose: iron supplementation, folate, dopamine agonists (non-pharmacological and pharmacological) vs: Placebo 效果: None None

cross-sectional study n=100

Assessment of Serum Ferritin Levels in Female Patients With Telogen Effluvium.

Dose: not applicable (observational; serum ferritin measured) vs: Placebo 效果: mean ferritin 24.30 vs 44.78 ng/mL < 0.001

Key Statistics

研究数量

30034

受试者

↔

Mixed

等级

Referenced Papers

[Restless leg syndrome. Diagnosis and treatment]. Review

Revista de neurologia None 8 次引用

Restless Leg Syndrome and Association with Serum NT Pro-CNP. Other

Neurology India 2026

Retrospective Review of 2851 Female Patients With Telogen Effluvium: A Single-Center Experience. Other

Journal of cosmetic … 2025 4 次引用

Iron Metabolism and the Role of Iron Therapy in Pediatric Restless Leg Syndrome. Review

Sleep medicine clinics 2025 2 次引用

Assessment of Serum Ferritin Levels in Female Patients With Telogen Effluvium. Other

Cureus 2025

Optimizing Restless Legs Syndrome Care: Integrating Rehabilitation into Multimodal Management. Review

JPMA. The Journal … 2025

Prevalence of Restless Leg Syndrome and Its Association With Iron Deficiency in Patients With Chronic Kidney Disease: A Cross-Sectional Observational … Other

Cureus 2025

Telogen Effluvium Following Coronavirus Disease-2019 Infection: A Retrospective Study of 113 Cases. Other

International journal of … 2025

Restless Leg Syndrome and Pregnancy. Review

Southern medical journal 2025

A comprehensive investigation of biochemical status in patients with telogen effluvium: Analysis of Hb, ferritin, vitamin B12, vitamin D, thyroid … Other

Journal of cosmetic … 2024 7 次引用

Iron Deficiency and Restless Sleep/Wake Behaviors in Neurodevelopmental Disorders and Mental Health Conditions. Other

Nutrients 2024 7 次引用

Post Covid telogen effluvium: the diagnostic value of serum ferritin biomarker and the preventive value of dietary supplements. a case … Other

Archives of dermatological … 2024 5 次引用

Iron Supplementation May Improve the Patient's Level of Satisfaction in Not-Low-Ferritin Telogen Effluvium: A Real-Life Observational Study. Other

Indian journal of … 2024 4 次引用

Brain Iron Dysregulation in Iron Deficiency Anemia-Related Restless Leg Syndrome Revealed by Neuron-Derived Extracellular Vesicles: A Case-Control Study. Other

Annals of neurology 2024 3 次引用

Iron deficiency-related symptoms in non-anemic whole blood donors. Other

Transfusion 2024 2 次引用

Clinical efficacy and safety of IV ferric carboxymaltose in restless legs syndrome: A meta-analysis of 537 patients. Meta-Analysis

Sleep medicine 2024 1 次引用

Evaluation of the relationship of digital phototrichogram findings of patients with diffuse hair loss with blood TSH, ferritin and vitamin … Other

Northern clinics of … 2024 1 次引用

Intersecting Pathways: Treating Cocaine Withdrawal and Restless Leg Syndrome with Iron and Buproprion. Case Report

Healthcare (Basel, Switzerland) 2024

Restless Legs Syndrome in Chronic Kidney Disease- a Systematic Review. Systematic Review

Tremor and other … 2023 32 次引用

Restless leg syndrome in patients with chronic kidney disease: a hospital-based study from Upper Egypt. Other

The International journal … 2023 14 次引用

Etiology, management, and outcomes of pediatric telogen effluvium: A single-center study in the United States. Other

Pediatric dermatology 2023 9 次引用

The genetic etiology of periodic limb movement in sleep. Meta-Analysis

Sleep 2023 8 次引用

Complementary and Integrative Approaches to Sleep Disorders in Children. Review

Child and adolescent … 2023 5 次引用

Micronutrient Deficiencies and Digital Computerized Phototrichogram Analysis in Telogen Effluvium: a Retrospective Correlation Study in a Tertiary Medical Center. Other

Dermatology practical & … 2023 4 次引用

The incidence, complications, and treatment of iron deficiency in pregnancy. Review

European journal of … 2022 109 次引用

Telogen effluvium in daily practice: Patient characteristics, laboratory parameters, and treatment modalities of 3028 patients with telogen effluvium. Other

Journal of cosmetic … 2022 22 次引用

Exploration of restless legs syndrome under the new concept: A review. Review

Medicine 2022 15 次引用

Behavioral sleep medicine-The need for harmonization of clinical best practice outcome measures in children and adolescents with intellectual or developmental … Review

Frontiers in psychiatry 2022 8 次引用

Nonscarring scalp alopecia: Which laboratory analysis should we perform on whom? Other

Turkish journal of … 2022 8 次引用

Evaluation of MCV/RDW Ratio and Correlations With Ferritin in Telogen Effluvium Patients. Other

Dermatology practical & … 2022 6 次引用

Does Dexmedetomidine Improve or Worsen Restless Leg Syndrome under Sedation: A Case Report and Extensive Review. Case Report

Case reports in … 2022 3 次引用

The Association of Serum Ferritin Levels With Non-scarring Alopecia in Women. Other

Cureus 2022 3 次引用

Restless Leg Syndrome and Sleep Disorders in Patients with Rheumatoid Arthritis and Its Relation with Anemia Parameters. Other

Acta medica (Hradec … 2021 13 次引用

Diagnostic and Treatment Considerations in Restless Legs Syndrome Complicated by Diabetic Neuropathy. Review

Current diabetes reports 2021 5 次引用

The role of iron repletion in adult iron deficiency anemia and other diseases. Review

European journal of … 2020 137 次引用

Comorbidities in alopecia areata: A systematic review and meta-analysis. Meta-Analysis

Journal of the … 2019 189 次引用

Neurologic conditions and disorders of uremic syndrome of chronic kidney disease: presentations, causes, and treatment strategies. Review

Expert review of … 2019 123 次引用

Restless legs syndrome and iron deficiency in adults with attention-deficit/hyperactivity disorder. Other

Sleep 2019 33 次引用

NonScarring Diffuse Hair Loss in Women: a Clinico-Etiological Study from tertiary care center in North-West India. Observational

Journal of cosmetic … 2019 25 次引用

Prevalence of Nutritional Deficiencies in Hair Loss among Indian Participants: Results of a Cross-sectional Study. Other

International journal of … 2017 43 次引用

Changes of serum trace elements level in patients with alopecia areata: A meta-analysis. Meta-Analysis

The Journal of … 2017 31 次引用

Restless leg syndrome in chronic hemodialysis patients in Mashhad hemodialysis centers. Other

Journal of renal … 2017 26 次引用

Vitamin and Mineral Deficiencies in Patients With Telogen Effluvium: A Retrospective Cross-Sectional Study. Other

Journal of drugs … 2016 56 次引用

Female Pattern Hair Loss: A Retrospective Study in a Tertiary Referral Center. Other

International journal of … 2016 28 次引用

Clinicoepidemiological Observational Study of Acquired Alopecias in Females Correlating with Anemia and Thyroid Function. Other

Dermatology research and … 2016 26 次引用

Insomnia and Restless Leg Syndrome in Patients Undergoing Chronic Hemodialysis in Rafsanjan Ali Ibn Abitaleb Hospital. Other

Nephro-urology monthly 2016 21 次引用

Importance of donor history of restless leg syndrome and pica to asses iron deficiency. Other

Transfusion and apheresis … 2016 10 次引用

Non-invasive method distinguishes chronic telogen effluvium from mild female pattern hair loss: clinicopathological correlation. Other

International journal of … 2016 6 次引用

Trichotillomania: Bizzare Patern of Hair Loss at 11-Year-old Girl. Case Report

Acta dermatovenerologica Croatica … 2016 6 次引用

Restless Leg Syndrome/Willis-Ekbom disease in women with iron deficiency anemia. Other

Ideggyogyaszati szemle 2016 6 次引用

Asthma as a disruption in iron homeostasis. Review

Biometals : an … 2016

Restless Leg Syndrome/Willis-Ekbom Disease Pathophysiology. Review

Sleep medicine clinics 2015 158 次引用

A Hospital-based Study to Determine Causes of Diffuse Hair Loss in Women. Other

Journal of clinical … 2015 41 次引用

Response to intravenous iron in patients with iron deficiency anemia (IDA) and restless leg syndrome (Willis-Ekbom disease). Other

Sleep medicine 2014 58 次引用

Disorders of heavy metals. Review

Handbook of clinical … 2014 52 次引用

Restless leg syndrome: a neglected diagnosis. Review

Nephro-urology monthly 2014 43 次引用

Acute telogen effluvium onset event is associated with the presence of female androgenetic alopecia: potential therapeutic implications. Other

Dermatologic therapy 2014 13 次引用

New treatment options for the management of restless leg syndrome. Review

The Journal of … 2014 7 次引用

Telogen effluvium as the first symptom of Crohn's disease in a child. Case Report

Annals of gastroenterology 2014 5 次引用

Is TrichoScan a new diagnostic method for diffuse hair loss? Other

Turkish journal of … 2014 5 次引用

Serum ferritin and vitamin d in female hair loss: do they play a role? Other

Skin pharmacology and … 2013 127 次引用

The diet factor in attention-deficit/hyperactivity disorder. Review

Pediatrics 2012 205 次引用

ADMET considerations for restless leg syndrome drug treatments. Review

Expert opinion on … 2012 6 次引用

Iron deficiency: beyond anemia. Review

Indian journal of … 2011 75 次引用

Iron deficiency in female pattern hair loss, chronic telogen effluvium, and control groups. Other

Journal of the … 2010 94 次引用

Diffuse hair loss in an adult female: approach to diagnosis and management. Review

Indian journal of … 2009 109 次引用

Hyperferritinemia in autoimmunity. Review

The Israel Medical … 2008 61 次引用

Nonhematological benefits of iron. Review

American journal of … 2007 61 次引用

The diagnosis and treatment of iron deficiency and its potential relationship to hair loss. Review

Journal of the … 2006 255 次引用

Medical treatment of noncicatricial alopecia. Review

Seminars in cutaneous … 2006 23 次引用

Decreased serum ferritin is associated with alopecia in women. Other

The Journal of … 2003 222 次引用

Iron, brain and restless legs syndrome. Other

Sleep medicine reviews 2001 48 次引用

Management of hair loss in women. Review

Dermatologic clinics 1993 38 次引用

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

常用剂量

general:: 18 mg/day (women)
deficiency:: 65-200 mg elemental iron/day

上限： 45 mg/day

研究中使用的剂量

剂量	持续时间	效果	N
various	--	Positive	--
None	--	Positive	90
None	--	Positive	--
None	--	Positive	150
iron supplementation, folate, dopamine agonists (non-pharmacological and pharmacological)	--	Positive	--
not applicable (observational; serum ferritin measured)	--	Negative	100
None	--	Neutral	113
None	--	Neutral	2851

最佳服用时间： On an empty stomach with vitamin C for best absorption; take 2 hours apart from calcium

Safety & Side Effects

已报告的副作用

⚠ Constipation (most common)
⚠ Nausea and stomach cramps
⚠ Dark or black stools
⚠ Iron overload with excessive supplementation (hemochromatosis risk)

已知相互作用

● Calcium supplements and dairy (reduce iron absorption by 50-60%)
● Proton pump inhibitors (omeprazole) and H2 blockers reduce absorption
● Tetracycline and quinolone antibiotics (mutual absorption reduction)
● Levothyroxine (iron reduces thyroid hormone absorption)

可耐受最高摄入量： 45 mg/day

在开始服用任何补充剂之前，请务必咨询您的医疗保健提供者。

Frequently Asked Questions

Does 铁 help with 缺铁性脱发?

Based on 73 studies with 30,034 participants, there is strong evidence from multiple clinical trials that 铁 may support 缺铁性脱发 management. Our evidence grade is A (Strong Evidence).

How much 铁 should I take for 缺铁性脱发?

Studies have used various dosages. A commonly studied range is 18 mg/day (women). Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of 铁?

Reported side effects may include Constipation (most common), Nausea and stomach cramps, Dark or black stools, Iron overload with excessive supplementation (hemochromatosis risk). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for 铁 and 缺铁性脱发?

We rate the evidence as Grade A (Strong Evidence). This rating is based on 73 peer-reviewed studies with 30,034 total participants. The overall direction of effect is mixed.

Related Evidence

其他成分用于缺铁性脱发

L-Lysine D

铁用于其他健康状况

休止期脱发 B 产后脱发 D

快速结论

基于73项研究（4项荟萃分析），共30,034名参与者。各研究结果不一。

Evidence Strength92%

High confidence

研究分析

RCT (0)Meta (4)Other (69)

对比替代方案

查看其他成分针对该健康状况的对比结果。

查看所有成分用于缺铁性脱发

了解更多

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