Physical Treatments and Therapies for Androgenetic Alopecia.
Study Design
- Loại nghiên cứu
- Review
- Can thiệp
- Physical Treatments and Therapies for Androgenetic Alopecia.
- Đối chứng
- Placebo
- Xu hướng hiệu quả
- Neutral
- Nguy cơ sai lệch
- Unclear
Abstract
Androgenetic alopecia, the most common cause of hair loss affecting both men and women, is typically treated using pharmaceutical options, such as minoxidil and finasteride. While these medications work for many individuals, they are not suitable options for all. To date, the only non-pharmaceutical option that the United States Food and Drug Administration has cleared as a treatment for androgenetic alopecia is low-level laser therapy (LLLT). Numerous clinical trials utilizing LLLT devices of various types are available. However, a myriad of other physical treatments for this form of hair loss have been reported in the literature. This review evaluated the effectiveness of microneedling, pulsed electromagnetic field (PEMF) therapy, low-level laser therapy (LLLT), fractional laser therapy, and nonablative laser therapy for the treatment of androgenetic alopecia (AGA). It also explores the potential of multimodal treatments combining these physical therapies. The majority of evidence in the literature supports LLLT as a physical therapy for androgenetic alopecia. However, other physical treatments, such as nonablative laser treatments, and multimodal approaches, such as PEMF-LLLT, seem to have the potential to be equally or more promising and merit further exploration.
Full Text
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Figure 1
Experimental results examining physical Treatments and Therapies for Androgenetic Alopecia, with data points illustrating key findings related to androgenetic alopecia, the most common cause of hair loss affecting both men and women, is typically treated using ph.
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Figure 2
Statistical analysis from research investigating physical Treatments and Therapies for Androgenetic Alopecia, comparing treatment groups and control conditions.
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Figure 3
Measured parameters from a study evaluating physical Treatments and Therapies for Androgenetic Alopecia, contributing to the overall assessment of androgenetic alopecia, the most common cause of hair loss affecting both men and women, is typically treated using ph.
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Figure 4
Graphical representation of outcomes in a study of physical Treatments and Therapies for Androgenetic Alopecia, highlighting trends observed across experimental conditions.
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Figure 5
Quantitative data from a study on physical Treatments and Therapies for Androgenetic Alopecia, presenting measured outcomes relevant to the investigation of androgenetic alopecia, the most common cause of hair loss affecting both men and women, is typically treated using ph.
chartTables
Table 1
| Study | AGA Diagnosis | Treatment Regimen | Treatment | Subject Demographics | Duration (Weeks) | Improvement in Hair Density (Total Hairs/cm2) |
|---|---|---|---|---|---|---|
| Kumar et al., 2018 [ | 2× daily treatment | Minoxidil 5% | 34 M | 12 | 1.89 ± 8.94 | |
| NH III-IV | 2× daily treatment, as well as | Minoxidil 5% | 34 M | 12 | 12.82 ± 6.82 | |
| Dhurat et al., 2013 [ | 2× daily treatment | Minoxidil 5% | 44 M | 12 | 22 | |
| NH III-IV | 2× daily treatment, as well as 1× weekly microneedling (with no minoxidil on day of microneedling) | Minoxidil 5% Microneedling | 50 M | 12 | 91.4 | |
| Choi and Park 2022 [ | NH II+ | 15 min LLLT and 10 min PEMF | PEMF and LLLT | 31 M, 9 F | 23 | 24.8 ± 2.65 |
| Sham | 28 M, 12 F | 23 | 6.5 ± 1.85 | |||
| Bureau et al., 2003 [ | NH I-VII | 30 min 3× per week | PEMF and Nutraceutical | 31 M, 9 F | 26 | 34 |
| Sham and placebo nutraceutical | 21 M, 8 F | 26 | 9 | |||
| Maddin et al., 1990 [ | 12 min | PEMF using Electrotricho-genesis | 30 M | 12 | 3.67 ± 6.72 * | |
| PEMF using Electrotricho-genesis | 30 M | 24 | 7.08 ± 8.59 * | |||
| NH III-IV | PEMF using Electrotricho-genesis | 30 M | 36 | 11.87 ± 10.61 * | ||
| Sham | 26 M | 12 | −1.97 ± 8.79 * | |||
| Sham | 26 M | 24 | 1.93 ± 8.3 * | |||
| Sham | 26 M | 36 | 5.61 ± 10.25 * | |||
| Maddin et al., 1992 [ | NH III-IV | 12 min | PEMF using Electrotricho-genesis | 14 M | 24 | 11.66 ± 1.38 * |
| 12 min | PEMF using Electrotricho-genesis | 14 M | 30 | 17.59 ± 1.98 * | ||
| Leavitt et al., 2009 [ | NH IIa-V | 15 min | LLLT using the HairMax | 71 M | 26 | 17.3 ± 11.9 * |
| Sham | 39 M | 26 | −8.9 ± 11.7 * | |||
| Kim et al., 2013 [ | NH III-VII | 18 min daily | LLLT using the Oaze 3R Helmet | 15 M and F | 24 | 17.2 ± 12.1 |
| Sham | 14 M and F | 24 | −2.1 ± 18.3 | |||
| Mai-Yi Fan et al., 2018 [ | NH IIa-V | 30 min | LLLT using the | 61 M | 24 | 6 ± 12.5 |
| Sham | 13 F | −2 ± 12.6 | ||||
| 11 min | LLLT using 9-beam HairMax LaserComb | 42 F | 26 | 20.2 ± 11.2 * | ||
| Sham | 21 F | 26 | 2.8 ± 16.5 * | |||
| 8 min | LLLT using 12-beam HairMax LaserComb | 39 F | 26 | 20.6 ± 11.6 * | ||
| Jimenez et al., 2014 [ | NH IIa-V | Sham | 18 F | 26 | 3.0 ± 9.3 * | |
| 15 min | LLLT using 7-beam HairMax LaserComb | 24 M | 26 | 18.4 ± 13.7 * | ||
| Sham | 14 M | 26 | 3.0 ± 9.3 * | |||
| 11 min, 3× per week | LLLT using 9-beam or HairMax Laser Comb or 12-beam HairMax Laser Comb | 21 M | 26 | 20.9 ± 13.5 * | ||
| Sham | 21 M | 26 | 9.4 ± 12.9 * | |||
| Lodi et al., 2021 [ | NH III-VI | 24 min | Blue LLLT | 20 M | 10 | 11 ± 3 |
| Lee et al., 2011 [ | L I-II | 10 treatments (every fortnight) | 1550 fractional Er/Glass Laser | 27 F | 20 | 57 ± 14 |
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